Available Technologies
# of Displayed Technologies: 10 / 11
Applied Category Filter (Click To Remove): Life & Health Sciences
System for automated high-speed imaging and genetic manipulation of C. elegans on agar media
TS-065892 — The Need
The microscopic worm C. elegans is a model animal studied in more than 1500 biological and medical research laboratories worldwide due to its genetic manipulability and optical transparency. In C. elegans research, the manual process of picking worms between plates presents a significant …
- College: College of Engineering (COE)
- Inventors: Fang-Yen, Christopher "Chris"; Alhalbi, Serge; Li, Zihao
- Licensing Officer: Randhawa, Davinder
A next generation intranasal trivalent Measles, Mumps and Covid vaccine
TS-064189 — The Need
The current global landscape demands innovative solutions to address the urgent need for a safe and efficacious SARS-CoV-2 vaccine, particularly for the vulnerable population of infants and children under 12 years old. Existing vaccines face challenges in terms of durability, cost, and sta…
- College: College of Veterinary Medicine
- Inventors: Li, Jianrong; Xu, Jiayu; Zhang, Yuexiu
- Licensing Officer: Dahlman, Jason "Jay"
Dual-payload Humanized Antibody-Drug Conjugate (DualADC) for targeted chemo-immunotherapy
TS-062822 — Humanized Antibody-drugs conjugate for chemo-immunotherapy of multiple cancer types
The Technology
Dr. Margaret Liu and colleagues have developed a dual-payload antibody-drug conjugate (DualADC) for chemo-immunotherapy utilizing a new humanized antibody that targets CD276, a surface receptor that is overexpressed in Triple-negative Breast Cancers (TNBCs), lung cancer (including non…
- College: College of Engineering (COE)
- Inventors: Liu, Xiaoguang "Margaret"; Zhou, Lufang
- Licensing Officer: Schworer, Adam
Preventative Human T-cell leukemia virus type 1 vaccine
TS-062421 — The Need: Addressing the Global HTLV-1 Epidemic with a Novel Vaccine
Human T cell leukemia virus type-1 (HTLV-1) is a significant global health concern, responsible for causing Adult T cell leukemia/lymphoma (ATLL) and human myelopathy/tropical spastic paraparesis (HAM/TSP). With over 10 million pe…
- College: College of Veterinary Medicine
- Inventors: Panfil, Amanda; Green, Patrick; Niewiesk, Stefan
- Licensing Officer: Dahlman, Jason "Jay"
MicroRNA-Based Methods and Compositions for the Diagnosis, Prognosis and Treatment of Solid Cancers
TS-062318 — The Need
Cancer is a significant health problem and a leading cause of death in developed countries. Solid cancers, including prostate, breast, lung, stomach, colon, and pancreatic cancers, pose particularly challenging diagnostic and treatment obstacles. Early detection of these cancers is crucial…
- College: College of Medicine (COM)
- Inventors: Croce, Carlo; Calin, George; Volinia, Stefano
- Licensing Officer: Willson, Christopher
Live Attenuated Mumps Virus-Based SARS-CoV-2 Vaccines for Infants and Children
TS-062231 — The Need: Addressing the Urgent Need for a Safe and Effective SARS-CoV-2 Vaccine for Infants and Children
The ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought about significant economic, emotional, and public health challenges worldwide. The pressing dema…
- College: College of Veterinary Medicine
- Inventors: Li, Jianrong; Boyaka, Prosper; Lu, Mijia; Zhang, Yuexiu
- Licensing Officer: Dahlman, Jason "Jay"
Novel method for attenuating live vaccine candidates for non-segmented negative-sense RNA viruses
TS-062213 — The Need: Preventing Respiratory Syncytial Virus (RSV) Infection and Disease
Respiratory Syncytial Virus (RSV) is a highly prevalent and dangerous pathogen responsible for significant morbidity and mortality, particularly in infants, young children, and immunocompromised individuals. Despite its gl…
- College: College of Veterinary Medicine
- Inventors: Li, Jianrong; He, Chuan; Lu, Mijia; Niewiesk, Stefan; Peeples, Mark; Xue, Miaoge; Zhang, Zijie; Zhao, Boxuan
- Licensing Officer: Dahlman, Jason "Jay"
Drug Delivery System for the Treatment of Neurological Diseases
TS-054464 — Novel drug delivery system that enables efficient transfer of FDA-approved drugs for the treatment of neurological injuries.
Traumatic brain and spinal cord injury cause devastating neurological deficits and long-term disability due to detrimental structural and functional alteration in neuronal circuits. Treatment of brain injury and neurological disorders has traditionally been challenging due to the inability to deli…
- College: College of Engineering (COE)
- Inventors: Lannutti, John; Fan, Fan; Tedeschi, Andrea
- Licensing Officer: Schultz, Teri
Antisense Oligonucleotide Development for Treatment of Spinal Muscular Atrophy
TS-037741 —
The SMN2 gene contains sequences that regulate the level of inclusion of SMN exon7 in SMN mRNA, and some of these act in a negative manner. Antisense oligonucleotides to block the negative regulating protein binding to these sites can increase inclusion of SMN exon 7 and thus, the amount of SMN being produced.
Spinal muscular atrophy (SMA) is an inherited disease affecting the central nervous system, peripheral nervous system, and skeletal muscle. It is present primarily in infants and children but can also develop in adults. About 10,000 to 25,000 children and adults are living with the disease in the …
- College: College of Medicine (COM)
- Inventors: Burghes, Arthur; McGovern, Vicki; Prior, Thomas
- Licensing Officer: He, Panqing
Novel Live Attenuated Vaccines for Human Metapneumovirus
TS-037675 — Novel method of using live attenuated vaccines to prevent infection of hMVP.
The Need: Human metapneumovirus (hMPV) is a prevalent pathogen causing acute respiratory tract disease in individuals of all ages, especially infants, children, the elderly, and immunocompromised individuals. Despite its global prevalence, there are currently no therapeutics or vaccines available fo…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Li, Jianrong; Wei, Yongwei; Zhang, Yu
- Licensing Officer: Dahlman, Jason "Jay"
