TS-065457 — The Need: In the realm of therapeutic development, there's a pressing need for precise targeting of dysregulated ribonucleoprotein (RNP) complexes to combat various diseases, particularly neurodegenerative disorders like ALS, Alzheimer’s, and Huntington’s diseases. Traditional metho…

TS-065456 — The Need In modern biological research, there is a pressing demand for technologies that enable precise mapping of RNA-protein interactions within Ribonucleoprotein (RNP) complexes. Traditional methods often lack the capability to pinpoint these interactions at the level of secondary structure moti…

TS-065455 — The Need: In modern biotechnology and biomedical research, there is an escalating demand for efficient tools that can accurately detect and analyze specific RNA sequences. The ability to precisely target and identify RNA molecules, particularly U-rich sequences, is crucial for various applications s…

TS-064831 — The Need: Urban historians, city planners, and preservationists require efficient tools to extract building-level information from historic Sanborn Fire Insurance maps, essential for understanding urban development over time. However, manual extraction is time-consuming and impractical due to the sh…

TS-063717 — The Need In the world of semiconductor material systems, the demand for advancements in optoelectronic and power electronic devices is ever-growing. The fabrication of semiconductor films, crucial for these applications, primarily relies on epitaxy technologies such as hydride vapor phase epitaxy (…

TS-063237 — Electronic Health Records (EHR) are used in over 88% of all US medical clinics to improve care and streamline data. In addition, they enable sharing of data to multiple providers dealing with the same patient, thereby enhancing efficiency and care. The Need In the last decade, medical practices…

TS-062692 — Chlorine is used in production of many products, such as many polymers like polyvinyl chloride, polyurethanes and chloroaromatics. It is also used extensively in pharmaceuticals, pesticides, fiber optics, hypochlorite bleaches, and other commodities. However, the current method of producing chlori…

TS-062682 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately 40% living the first-year post-diagnosis and 17% in the second year. The Need Oncolytic viruses (OVs) are a prom…

TS-062679 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately 40% living the first-year post-diagnosis and 17% in the second year. The Need Oncolytic viruses (OVs) are a prom…

TS-062677 — Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths. The most common cancers are breast, lung, colon and rectum and prostate cancers. The Need Current cancer treatments mainly rely on chemotherapy, radiation, surgery and bon…

TS-062554 — The Need: Intracellular RNA fluorescence labeling is a crucial technique for studying cellular processes and understanding gene expression. However, the conventional MS2 labeling method using protein fusion labels can have drawbacks, such as increased mass, potential steric accessibility issues, and…

TS-062231 — The Need: Addressing the Urgent Need for a Safe and Effective SARS-CoV-2 Vaccine for Infants and Children The ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought about significant economic, emotional, and public health challenges worldwide. The pressing dema…

TS-062218 — The Need: Flavor Modulating Compounds for Healthier Food and Beverages In a world where taste preferences drive consumer choices, the demand for nutritious and palatable food and beverages remains at an all-time high. However, many nutrient-rich foods, such as vegetables and whole grains, often possess bitter flavors that can be unappealing to consumers. To make these foods more enjoyable and mask the bitterness, manufacturers frequently resort to excessive amounts of unhealthy additives like fats, sugars, and salts. The result is a trade-off between taste and health, leaving consumers seeking a solution that provides both flavor satisfaction and nutritional benefits. The Technology: Innovative Flavor Modulating Compounds Our technology offers a groundbreaking solution to the challenge of balancing taste and health in food and beverages. Developed as additives for the food industry, our flavor modulating compounds effectively block or modulate bitter flavors, enabling significant reductions in the need for added sugars and salts. By utilizing these compounds, manufacturers can maintain the palatability of their products without compromising on nutritional value. Commercial Applications: Unlocking the Potential The versatility of our flavor modulating compounds opens up numerous commercial applications across various food and beverage categories: Healthy Snacks: Create nutritious and appealing snacks using bitter-rich ingredients, like vegetable chips and whole grain crackers, while minimizing the need for excessive unhealthy additives. Low-Sugar Beverages: Develop refreshing drinks with reduced sugar content, ensuring that consumers enjoy a satisfying taste experience without the guilt of excess sugar consumption. Nutrient-Enhanced Foods: Enhance the flavor profile of nutrient-rich foods, such as salads and soups, to make them more enjoyable, encouraging healthier eating habits. Confectionery: Improve the taste of health-focused sweets and candies, enabling confectionery brands to cater to health-conscious consumers. Ready-to-Eat Meals: Incorporate flavor modulating compounds into pre-packaged meals, enhancing taste while adhering to nutritional guidelines. Benefits/Advantages: Elevating Consumer Experience and Market Appeal Our flavor modulating compounds offer an array of advantages for food and beverage manufacturers, making them a valuable addition to any product development strategy: Healthier Product Profiles: Enable the creation of low-sugar, low-salt products, supporting consumer health and well-being. Uncompromised Taste: Maintain delicious flavor profiles while reducing or eliminating unhealthy additives, satisfying consumer cravings. Market Differentiation: Stand out in a crowded market by offering healthier alternatives without sacrificing taste. Health-Conscious Appeal: Attract health-conscious consumers seeking better-for-you options, expanding your target audience. Regulatory Compliance: Align with evolving nutritional guidelines and regulations, positioning your products for long-term success. In conclusion, our flavor modulating compounds revolutionize the way food and beverages are formulated. By addressing the commercial need for healthier options without compromising on taste, our technology unlocks vast opportunities for manufacturers to create products that appeal to consumers' palates and prioritize their well-being. Join us on this journey towards a future of delightful, nutritious, and flavorful food and drink experiences.

TS-061850 — High-quality beta-gallium oxide (β-Ga2O3) based semi-insulating layers enable high power/high-frequency electronics, ultraviolet optoelectronics, and more.

TS-060181 — The Need Food coloring is an important factor of the consumer's perception of the quality and flavor of a food product, boosting the product's overall success. Not only does it provide a different color to food products, it even helps prevent color loss during long-term storage. However, in…

TS-048588 — A lightweight power module that reduces loop stray inductance while maintaining good electrical insulation and thermal dissipation.

TS-048216 — A soft robotic gripper design which incorporates layer jamming as a means for creating tunable stiffness control and higher load capacities. For a closely related technology, please visit https://oied.osu.edu/find-technologies and type "T2021-245" in the search field.

TS-042856 — A Framework and Automatization process designed to determine the functionality of Embedded Digital Devices.

TS-042088 — Transistor structure with high breakdown voltage at high frequency operation

TS-042066 — A novel hybrid adhesive that combines the non-toxic, high strength properties of methacrylate adhesives with the bonding characteristics of polyurethanes