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Introducing HexaPro VSV: A Breakthrough in COVID-19 Vaccine Technology
TS-064191 — The emergence of SARS-CoV-2 variants poses a significant challenge to existing COVID-19 vaccines, necessitating the development of a more durable and broadly protective solution. Current vaccines show reduced efficacy over time and struggle against Variants of Concern (VoCs) such as Omicron. Addre…
  • College: College of Veterinary Medicine
  • Inventors: Li, Jianrong; Chamblee, Michelle; Lu, Mijia; Zhang, Yuexiu
  • Licensing Officer: Dahlman, Jason "Jay"

A next generation intranasal trivalent Measles, Mumps and Covid vaccine
TS-064189 — The Need The current global landscape demands innovative solutions to address the urgent need for a safe and efficacious SARS-CoV-2 vaccine, particularly for the vulnerable population of infants and children under 12 years old. Existing vaccines face challenges in terms of durability, cost, and sta…
  • College: College of Veterinary Medicine
  • Inventors: Li, Jianrong; Xu, Jiayu; Zhang, Yuexiu
  • Licensing Officer: Dahlman, Jason "Jay"

Aqueous Zn-Tetrazine Batteries
TS-064150 — The Need As the global demand for energy storage devices continues to surge, the limitations of conventional lithium-ion batteries become increasingly evident. Dwindling lithium reserves are unable to meet the burgeoning needs of modern society, necessitating the exploration of alternative solution…
  • College: College of Arts & Sciences
  • Inventors: Zhang, Shiyu; Walter, Christopher
  • Licensing Officer: Randhawa, Davinder

Metal Matrix Composites Reinforced by High Entropy Alloys
TS-063364 — Experience the future of advanced materials—our metal matrix composites offer a revolutionary approach to meeting the demands of modern industries. Elevate your products, enhance performance, and reduce costs with our groundbreaking technology. For a closely related technology, please visit https://oied.osu.edu/find-technologies and type "T2017-051" in the search field.
In the aerospace, defense, and automotive industries, there is a pressing demand for advanced materials that combine low weight, high strength, exceptional wear resistance, and superior high-temperature performance. Traditional methods using ceramic particles as reinforcements in aluminum matrix c…
  • College: College of Engineering (COE)
  • Inventors: Luo, Alan; Huang, Xuejun; Zhang, Jianyue
  • Licensing Officer: Zinn, Ryan

Live Attenuated Mumps Virus-Based SARS-CoV-2 Vaccines for Infants and Children
TS-062231 — The Need: Addressing the Urgent Need for a Safe and Effective SARS-CoV-2 Vaccine for Infants and Children The ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought about significant economic, emotional, and public health challenges worldwide. The pressing dema…
  • College: College of Veterinary Medicine
  • Inventors: Li, Jianrong; Boyaka, Prosper; Lu, Mijia; Zhang, Yuexiu
  • Licensing Officer: Dahlman, Jason "Jay"

Novel method for attenuating live vaccine candidates for non-segmented negative-sense RNA viruses
TS-062213 — The Need: Preventing Respiratory Syncytial Virus (RSV) Infection and Disease Respiratory Syncytial Virus (RSV) is a highly prevalent and dangerous pathogen responsible for significant morbidity and mortality, particularly in infants, young children, and immunocompromised individuals. Despite its gl…
  • College: College of Veterinary Medicine
  • Inventors: Li, Jianrong; He, Chuan; Lu, Mijia; Niewiesk, Stefan; Peeples, Mark; Xue, Miaoge; Zhang, Zijie; Zhao, Boxuan
  • Licensing Officer: Dahlman, Jason "Jay"

High Efficiency LED Designs Using Quantum Well Engineering
TS-057127 — Achieving high efficiency LEDs with green, amber and longer wavelengths using III-nitride/II-IV-nitride heterostructures as the active media.
Although extensive research and development over the past two decades has resulted in close to 100% external quantum efficiency (EQE) of InGaN based blue light emitting devices, efficiency of the longer visible wavelength emitting devices has remained relatively low. Spontaneous polarization origi…
  • College: College of Engineering (COE)
  • Inventors: Zhao, Hongping; Zhang, Kaitian
  • Licensing Officer: Randhawa, Davinder

Protecting Bluetooth Low Energy from Address Tracking When Using Whitelisting
TS-052807 — Bluetooth Low Energy (BLE) is ubiquitous today due to its extremely low energy consumption and relatively large communication coverage. However, the devices communicated through Bluetooth are subject to address tracking attacks, where a nearby attacker can associate Bluetooth addresses to particul…
  • College: College of Engineering (COE)
  • Inventors: LIN, ZHIQIANG; Zhang, Yue
  • Licensing Officer: Mess, David

Probiotic strains for reducing antibiotic resistance and modulating gut health
TS-037818 — A novel advancement to mitigate antibiotic resistance in the ecosystem.
The Need In today's world, the rapid emergence of antibiotic resistance (AR) poses a serious threat to public health, making it crucial to explore alternative strategies to combat this issue. Traditional approaches targeting pathogenic bacteria alone have proven insufficient due to the complexi…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Wang, Hua; Wang, Zihua; Zhang, Lu; Zhou, Yang
  • Licensing Officer: Dahlman, Jason "Jay"

Novel Live Attenuated Vaccines for Pneumoviruses
TS-037753 — A method to create vaccines for pneumoviruses, using recombinant viruses.
The Need Pneumoviruses consist of pathogens that target the upper respiratory tract within their specific hosts. These include many important human and animal pathogens, such as human respiratory syncytial virus (hRSV), hMPV, bovine RSV, pneumonia virus of mice (PVM), and avian metapneumovirus (aMP…
  • College: College of Veterinary Medicine
  • Inventors: Li, Jianrong; Cai, Hui; Peeples, Mark; Wang, Rongzhang
  • Licensing Officer: Dahlman, Jason "Jay"

Method to enhance light extraction efficiency in tunnel-injected III-Nitrate ultraviolet LEDs
TS-037365 — A novel method to enhance the transverse-electric and transverse-magnetic polarized light via relfective surfaces on top of a tunnel junction based LED structure.
III-Nitride ultraviolet light emitting diodes (UV LEDs) have a variety of promising applications, including sterilization and water purification. Currently, UV LEDs use an absorbing p-GaN top layer for hole injection, which reduces light extraction efficiency to lower than 20%. UV light emissions …
  • College: College of Engineering (COE)
  • Inventors: Rajan, Siddharth; Akyol, Faith; Jamal-Eddine, Zane; Zhang, Yuewei
  • Licensing Officer: Zinn, Ryan

U+RSW - A Break-Through Process for Dissimilar Metal Joining in Automotive Industries
TS-036907 — A welding technique that joins two dissimilar metals.
Resistance spot welding (RSW) is critical to automobile manufacturing, with 3,000 to 5,000 spot welds per vehicle. As consumers seek vehicles with better fuel economy, automobile manufacturers have replaced parts built from heavy metals, such as advanced high-strength steel (AHSS), with lighter al…
  • College: College of Engineering (COE)
  • Inventors: Zhang, Wei; Kimchi, Menachem; Lu, Ying "ying"; Mayton, Ellis
  • Licensing Officer: Zinn, Ryan

Method and Device to Monitor & Control Efficiency of the Friction Welding Process
TS-015293 — A device that can be readily attached to inertia or direct drive friction welding equipment to determine energy efficiency in-situ during welding, providing real-time feedback for improving control.
Friction welding is a category of solid-state welding processes that uses frictional heat generation at the weld interface to plasticize the work pieces and produce a metallurgical bond. The welding parameters used in large-scale industrial production are typically determined via trial and error. …
  • College: College of Engineering (COE)
  • Inventors: Zhang, Wei; Mahaffey, David; Semiatin, Sheldon; Senkov, Oleg; Tung, Daniel
  • Licensing Officer: Zinn, Ryan

Low Flux DC/DC Converter for Consumer Electronics
TS-014962 — A more efficient DC/DC converter composed of a front-stage circuit that allows for step-down DC/AC topology
DC/DC converters are used by hybrid electric vehicles, laptops, desktops, data-com systems, etc. Converters that optimize conversion of voltages last longer and improve energy efficiency. Therefore, improvements to existing converters could reduce time and money spent by manufacturers on faulty, l…
  • College: College of Engineering (COE)
  • Inventors: Wang, Jin; Zhang, Xuan; Zou, Ke
  • Licensing Officer: Ashouripashaki, Mandana

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