Small Molecule USP30 Inhibitors for the Treatment and Prevention of Cardiomyopathy
TS-066773 — The Need
Cardiomyopathy, a disease of the heart muscle, poses significant public
health challenges due to its diverse causes, symptoms, and potential complications, including heart failure and arrhythmias. With cardiomyopathy often induced by drugs, such as anthracyclines used in chemotherapy, ther…
- College: College
of Medicine (COM)
- Inventors: Sun, Nuo; Krigman, Judith; Yang, Mingchong; Zhang, Ruohan
- Licensing Officer: Willson, Christopher
SCTaware: Empowering Health Equity through Virtual Sickle Cell Trait Education
TS-062440 — The Need: Sickle Cell Trait (SCT) affects a significant portion of the population, posing a pressing public
health concern. Lack of awareness and limited access to understandable information about SCT's reproductive implications contribute to health disparities among affected individuals. In-per…
- College: College
of Arts & Sciences
- Inventors: Chan, Peter; McCorkle, Benson; Shen, Yvette
- Licensing Officer: Panic, Ana
A novel VSV-based vaccine platform for Zika virus
TS-062261 — The Need: Addressing the Zika Virus Outbreak
The Zika virus outbreak, which started in South America and quickly became a global public
health issue, has led to severe neurological disorders, birth defects, and other health complications in affected populations. Despite efforts to combat the virus,…
- College: College
of Medicine (COM)
- Inventors: Peeples, Mark; Li, Jianrong
- Licensing Officer: Bhatti, Hamid
Live Attenuated Mumps Virus-Based SARS-CoV-2 Vaccines for Infants and Children
TS-062231 — The Need: Addressing the Urgent Need for a Safe and Effective SARS-CoV-2 Vaccine for Infants and Children
The ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought about significant economic, emotional, and public
health challenges worldwide. The pressing dema…
- College: College
of Veterinary Medicine
- Inventors: Li, Jianrong; Boyaka, Prosper; Lu, Mijia; Zhang, Yuexiu
- Licensing Officer: Willson, Christopher
Live vaccine candidate for Chagas disease
TS-044084 —
Trypanosoma cruzi is a protozoan parasite that causes Chagas disease, a PRV-eligible disease that is the leading cause of heart failure in Latin America. Due to migration of infected hosts from endemic regions, Chagas disease is also a growing public
health concern in the USA and other migrant des…
- College: College
of Medicine (COM)
- Inventors: McGwire, Bradford
- Licensing Officer: He, Panqing