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Three-dimensional cellular automation codes for solidification microstructure and porosity simulation of multi-component alloys
TS-063911 — Porosity formation during the solidification of aluminum-based alloys, induced by hydrogen gas and alloy shrinkage, presents a significant challenge for industries relying on high-performance solidification products such as castings, welds, and additively manufactured components. This issue advers…
  • College: College of Engineering (COE)
  • Inventors: Luo, Alan; Gu, Cheng
  • Licensing Officer: Zinn, Ryan

A Novel MIMO Architecture for Multi-user Power line communication
TS-062843 — This MIMO-PLC architecture is the first scalable MIMO architecture on a single power line. It improves the throughput for power line communication (PLC) by utilizing the existing power delivery infrastructure and allows for high data rates in rural areas.
Home networking and the Internet of Things (IoT), especially voice and video communications, require high throughput, reliable coverage, and sustainable connectivity. However, the performance is dramatically decreased when the wireless signals go through the walls and ceilings. The densely deploye…
  • College: College of Engineering (COE)
  • Inventors: Srinivasan, Kannan; Chen, Bo; Guruvenkata, Vivek; Sun, Wei
  • Licensing Officer: Phillips, Taylor

Surrogates for Concrete Dividers
TS-062834 — Road departure can be extremely dangerous for vehicles. Some vehicles are equipped with road departure mitigation systems to prevent this from happening. However, testing these systems can be difficult and costly, as it involves crashing vehicles into roadside objects. The concrete divider surr…
  • College: College of Engineering (COE)
  • Inventors: Chen, Chi-Chih; Chen, Yaobin; Chien, Stanley; Lin, Jun; Sherony, Rini; Yi, Qiang
  • Licensing Officer: Zinn, Ryan

Surrogates for Metal Guardrails
TS-062797
Road departures remain a significant source of traffic accidents. Tools for limiting road departures are needed to reduce accidents and improve safe driving conditions. The Ohio State University researcher Dr. Chi-Chih Chen, along with a team of researchers, has developed a novel metal guardrai…
  • College: College of Engineering (COE)
  • Inventors: Chen, Chi-Chih; Chen, Yaobin; Chien, Stanley; Lin, Jun; Sherony, Rini
  • Licensing Officer: Zinn, Ryan

Addressing the Challenges in HCC Treatment with Innovative Technology
TS-062690 — Novel niclosamide analogues with improved bioavailability and mitigated dose-limiting toxicities.
Hepatocellular carcinoma (HCC) poses a significant global health challenge, being a predominant form of liver cancer with high mortality rates. The disease exhibits sexual dimorphism, disproportionately affecting males. The Need Despite the crucial role of androgen receptors (AR) in HCC progress…
  • College: College of Pharmacy
  • Inventors: Coss, Christopher; Cheng, Jeffrey; Cheng, Xiaolin; Kulp, Samuel; Li, Tom; Montgomery, Emma; Xing, Enming
  • Licensing Officer: Schultz, Teri

Transducin β-like protein 1 X-Linked Selective Degraders as Anti-cancer Therapeutics
TS-062685 — Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths. The most common cancers are breast, lung, colon and rectum and prostate cancers. The Need Current cancer treatments mainly rely on chemotherapy, radiation, surgery and bon…
  • College: College of Pharmacy
  • Inventors: Cheng, Xiaolin; Alinari, Lapo; Li, Pui-Kai "Tom"; Yang, Rui
  • Licensing Officer: Taysavang, Panya

Advanced AAV Gene Therapy Characterization Technique
TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …
  • College: College of Arts & Sciences
  • Inventors: Wysocki, Vicki; Cleary, Sean; Du, Chen
  • Licensing Officer: Dahlman, Jason "Jay"

Dual Androgen Receptor/AKR1C3 Inhibitors for Prostate Cancer
TS-062605 — The Need: Castration-resistant prostate cancer (CRPC) poses a significant challenge in oncology, with existing therapies often leading to resistance and disease progression. Key drivers of resistance include the androgen receptor (AR) and aldo-keto reductase family 1 member C3 (AKR1C3). Novel treat…
  • College: College of Pharmacy
  • Inventors: Li, Pui-Kai "Tom"; Cheng, Xiaolin; Kong, Xiaotian; Xing, Enming
  • Licensing Officer: Schworer, Adam

RF Energy Harvesting Wireless Mobile Device Charger
TS-062601 — Only a small fraction of the radio frequency (RF) energy transmitted by smartphones and other wireless devices is used to communicate with a wireless access point. It would be useful to collect or harvest the unused RF signals in order to convert them to direct current (DC) power and supplement th…
  • College: College of Engineering (COE)
  • Inventors: Chen, Chi-Chih; Koksal, C. Emre; Shroff, Ness; Tallos, Roland
  • Licensing Officer: Zinn, Ryan

Passive RF Rectifier Circuit Design with Harmonic Harvester
TS-062596 — Conventional rectifying circuit designs convert alternating-current (AC) signals into direct-current (DC) signals via the used of diodes. Low-barrier Schottky diodes are used in low AC power cases such as with ambient radio frequency (RF) signals. Ideally, each diode is only turned on during the p…
  • College: College of Engineering (COE)
  • Inventors: Chen, Chi-Chih
  • Licensing Officer: Zinn, Ryan

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