IDEAS: Revolutionizing Early Childhood Education with Automated Interaction Analysis
TS-065825 — The Need: In early childhood education settings, understanding children's interactions, both social and linguistic, is paramount for effective teaching and development monitoring. However, manual observation and analysis of these interactions can be time-consuming and subjective, hindering educa…
- College: College of Education & Human Ecology
- Inventors: Gonzalez Villasanti, Hugo "Hugo"; Justice, Laura
- Licensing Officer: Dahlman, Jason
"Jay"
Intracellular Targeting by Monoclonal Antibodies
TS-064581 — Antibodies are essential therapeutic modalities for treating a plethora of different diseases, ranging from cancer, autoimmune disorders, degenerative diseases, and inflammation. The FDA approved the first antibody over three decades ago, and since more than 570 have been studied in clinical trials,…
- College: College of Arts & Sciences
- Inventors: Magliery, Thomas; Do, Jamie; Han, Jeong Min "Mina"; Zhu, Ian
- Licensing Officer: Dahlman, Jason
"Jay"
How Are You Feeling Today? Organizational Mental Health Indicator and Real-Time Help Application
TS-064244 — The Need: Organizations, particularly college campuses, are facing a growing challenge in addressing student mental health issues. The rising prevalence of severe psychological problems, anxiety disorders, and depression among students necessitates a proactive and effective solution. The existing ga…
- College: College of Engineering (COE)
- Inventors: Ezell, Jonathan; Kaufman, Michael
- Licensing Officer: Dahlman, Jason
"Jay"
Novel use of novobiocin to potentiate the antimicrobial efficacy of polymyxins
TS-062439 — The Need: Addressing the Growing Threat of Gram-Negative Bacterial Infections
Gram-negative bacterial pathogens, including Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae, are responsible for more than 35% of common hospital-acquired infections. These no…
- College: College of Arts & Sciences
- Inventors: Kahne, Daniel; Baidin, Vadim; Mandler, Michael; Ruiz, Natividad
- Licensing Officer: Dahlman, Jason
"Jay"
Visual Function Mapping Technology: Enhancing Vision Care and Diagnostics
TS-062335 — The Need: In the field of ophthalmology and vision care, there is a critical need for accurate and comprehensive measurements of visual function over the entire visual field. Conditions such as glaucoma, age-related macular degeneration (AMD), diabetes, stroke, pituitary disease, brain tumors, and n…
- College: College of Arts & Sciences
- Inventors: Lu, Zhong-Lin; Lesmes, Luis; Xu, Pengjing "PJ"; Yu, Deyue
- Licensing Officer: Dahlman, Jason
"Jay"
Generation of T cell-specific CXCR3 Transgenic mouse
TS-062320 — The Need: Addressing Susceptibility to Cutaneous Leishmaniasis
Cutaneous leishmaniasis, caused by the intracellular parasite Leishmania major and transmitted by sand flies, poses a significant threat to susceptible populations. This disfiguring disease results in large skin lesions, impacting both …
- College: College of Arts & Sciences
- Inventors: Satoskar, Abhay; Oghumu, Steve
- Licensing Officer: Dahlman, Jason
"Jay"
PERSONAL PROTECTIVE EQUIPMENT FROM ELECTROSPUN FLEXIBLE FIBER MATS
TS-062224 — The Need: Advancing Nonwoven Fibrous Webs for Personal Protective Equipment
The demand for high-performance personal protective equipment (PPE) has been escalating rapidly, necessitating improved nonwoven materials that can meet stringent safety requirements. Traditional nonwoven fibrous webs lack …
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Puskas, Judit
- Licensing Officer: Dahlman, Jason
"Jay"
Localized Cylindrical Drug Delivery to Prevent Vascular Restenosis
TS-062216 — The Need: Addressing Vascular Restenosis with Extended Drug Delivery
Vascular restenosis poses a significant medical challenge in the United States, particularly in cases of coronary artery disease treated with bypass grafting. The current methods involve using drug-loaded polymer formulations to d…
- College: College of Engineering (COE)
- Inventors: Lannutti, John
- Licensing Officer: Dahlman, Jason
"Jay"
Mini-PCDH15 for treatment of deafness
TS-050433 — A gene therapy solution for Usher Syndrome Type 1F.
Mutations in PCDH15 cause Usher 1F, a recessive syndrome characterized by profound congenital deafness and absence of vestibular function, and progressive blindness beginning in the second decade. Because patients who lack hearing and balance rely on vision for communication and mobility, the late…
- College: College of Arts & Sciences
- Inventors: Sotomayor, Marcos
- Licensing Officer: Dahlman, Jason
"Jay"
CXCR3-GFP knock-in mouse
TS-038221 — A knock-in murine model that expresses high levels of GFP in CXCR3 positive cells.
Chemokines are typically small, secreted molecules that participate in leukocyte trafficking, recruitment, and activation. They also play roles in normal and pathological processes including allergic responses, infectious and autoimmune disease, angiogenesis, inflammation, and tumor growth and met…
- College: College of Arts & Sciences
- Inventors: Satoskar, Abhay; Oghumu, Steve
- Licensing Officer: Dahlman, Jason
"Jay"
Immunomodulating agents engineered from Notch receptor ligand extracellular domains
TS-036760 — Immunomodulating agents have been engineered from Notch receptor ligand extracelluar domains. These are useful for stimulating the immune system.
The Notch signaling pathway is important in immune cell differentiation and maturation. As a result, it has been shown that Notch receptor signaling can promote or suppress adaptive immune responses depending on the particular ligands and receptors involved. A set of native protein-inspired biolog…
- College: College of Arts & Sciences
- Inventors: Magliery, Thomas; Carbone, David; Dikov, Mikhail; Long, Nicholas; Sullivan, Brandon; Tchekneva, Elena
- Licensing Officer: Dahlman, Jason
"Jay"
Multi-carrier processing in auditory prosthetic devices
TS-014871 — Encoding strategy for improvement of speech understanding in a noisy environment for audiotory prosthetic devices.
There are about 275 million adults globally with moderate to severe hearing loss and 360 million adults with mild hearing loss. The current solutions to allow these people to hear better include hearing aids, hearing loss counseling, cochlear implants, alerting devices, and other communication aid…
- College: College of Arts & Sciences
- Inventors: Apoux, Frederic; Healy, Eric
- Licensing Officer: Dahlman, Jason
"Jay"
Self-Assembly of Therapeutic-Agent Nanostructures
TS-014812 — An improved delivery mechanism has been developed for hydrophobic drugs such as camptothecin which will increase chemotherapeutic efficacy.
Many cancer therapeutics exhibit extremely toxic side effects or have limited efficacy due to low bio-availability. Existing drug delivery technologies can add excessive mass to the therapeutic, grossly expanding the dosage necessary for response. Camptothecin (CPT) is a naturally occurring compou…
- College: College of Arts & Sciences
- Inventors: Parquette, Jonathan; Grinstaff, Mark; Kaplan, Jonah; Kim, Se Hye
- Licensing Officer: Dahlman, Jason
"Jay"