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Cyclic Cell-Penetrating Peptides: Revolutionizing Intracellular Delivery
TS-073895 — The Need In the rapidly evolving field of biotechnology and pharmaceuticals, there is a critical need for efficient delivery mechanisms to transport therapeutic agents directly into cells. Cell-penetrating peptides (CPPs) initially were considered a potential solution. Short sequences of amino acid…
  • College: College of Arts & Sciences
  • Inventors: Pei, Dehua
  • Licensing Officer: Dahlman, Jason "Jay"

NanoChitinase: A Truncated-Enzyme, Polymer-Nanoparticle Biocoating for Preventing Post-Harvest Fungal Spoilage
TS-072614 — A highly stable, edible, nano-engineered chitinase formulation that provides superior antifungal protection for fruits, vegetables, and seeds by combining an enhanced chitinase variant with biodegradable polymer nanoparticles for extended shelf life and reduced post-harvest losses.
Post-harvest fungal spoilage remains one of the most costly challenges in global food supply chains, with up to 40–50% losses in onions and strawberries reported in major producing regions. Conventional chemical fungicides face increasing regulatory pressure, safety concerns, and resistance …
  • College: College of Engineering (COE)
  • Inventors: Wood, David; Deeba, Farah; Rappleye, Chad; Watkins, Davita
  • Licensing Officer: Dahlman, Jason "Jay"

Breaking the Cycle of Ehrlichiosis: A Novel RipE-Based Vaccine and Detection Platform
TS-072613 — A novel vaccine and diagnostic platform targeting the conserved Ehrlichia virulence factor RipE offers the first pan-Ehrlichia solution for preventing and detecting tick-borne ehrlichiosis in humans and animals.
Tick-borne ehrlichiosis cases continue to rise globally, yet no licensed human vaccine exists and current diagnostic tools remain limited. Existing approaches struggle due to the pathogen’s antigenic variability, intracellular lifecycle, and lack of classical surface PAMPs, hindering effecti…
  • College: College of Veterinary Medicine
  • Inventors: Rikihisa, Yasuko
  • Licensing Officer: Dahlman, Jason "Jay"

Unlocking Hidden Opportunities: The Power of Multi-Solution Spatial Aggregation
TS-067434 — The Need Spatial aggregation is crucial in numerous industries where data from low-level spatial units, such as census blocks, must be grouped into larger, meaningful regions. Traditional approaches often struggle with the computational complexity of these tasks and tend to focus on finding a singl…
  • College: College of Arts & Sciences
  • Inventors: Xiao, Ningchuan
  • Licensing Officer: Dahlman, Jason "Jay"

Cyclic Cell-Penetrating Peptides: Revolutionizing Intracellular Delivery
TS-066751 — The Need In the rapidly evolving field of biotechnology and pharmaceuticals, there is a critical need for efficient delivery mechanisms to transport therapeutic agents directly into cells. Cell-penetrating peptides (CPPs) initially were considered a potential solution. Short sequences of amino acid…
  • College: College of Arts & Sciences
  • Inventors: Pei, Dehua
  • Licensing Officer: Dahlman, Jason "Jay"

Advanced Sensor Arrays for Precise Gas Identification and Analysis
TS-066250 — A cutting-edge sensor system featuring p-n junctions in MOS materials for accurate detection and identification of gases.
In various industries, there is a growing demand for highly selective and sensitive gas sensors capable of accurately identifying specific gases within complex mixtures, addressing challenges in environmental monitoring, industrial safety, and healthcare diagnostics. This innovative sensor syst…
  • College: College of Arts & Sciences
  • Inventors: Dutta, Prabir; Govindhan, Maduraiveeran; Mondal, Suvra; Sun, Chenhu
  • Licensing Officer: Dahlman, Jason "Jay"

Revolutionary NO Sensor for Highly Selective and Sensitive Gas Detection
TS-066249 — A novel sensor leveraging WO3 and Cr2O3 for selective NO detection in harsh environments and breath analysis with high sensitivity at ppb levels.
There is a critical demand for advanced gas sensors capable of selectively detecting nitric oxide (NO) in diverse applications such as environmental monitoring, industrial processes, and medical diagnostics, particularly in challenging environments with interfering gases like carbon monoxide (CO).…
  • College: College of Arts & Sciences
  • Inventors: Dutta, Prabir; Govindhan, Maduraiveeran; Mondal, Suvra; Sun, Chenhu
  • Licensing Officer: Dahlman, Jason "Jay"

Metal oxide-based resistive type sensor for the detection of carbon monoxide at room temperature
TS-066246 — Our innovative CO sensor utilizes hydrated ruthenium oxide to detect carbon monoxide within a gas mixture with high sensitivity and selectivity at temperatures ranging from 25°C to 300°C.
Reliable and low-cost CO sensors with high sensitivity and selectivity are essential for environmental safety and industrial control, particularly to monitor combustion environments, automotive emissions, and various industrial processes, ensuring compliance with regulations and minimizing health …
  • College: College of Arts & Sciences
  • Inventors: Dutta, Prabir; Adeyemo, Adedunni
  • Licensing Officer: Dahlman, Jason "Jay"

Compact High-Temperature Solid-State Potentiometric Oxygen Sensor
TS-066235 — Oxygen sensors are crucial for monitoring oxygen levels in combustion and industrial processes, but current sensors require complex plumbing for reference gas, limiting their placement and operational temperature range. There is a pressing need for a robust, high-temperature oxygen sensor that is …
  • College: College of Arts & Sciences
  • Inventors: Dutta, Prabir; Akbar, Sheikh; Ramasamy, Ramamoorthy; Routbort, Jules; Singh, Dileep; Spirig, John
  • Licensing Officer: Dahlman, Jason "Jay"

Advancing Canine Lung Cancer Care: Precision Diagnostics and Targeted Therapies
TS-065859 — FIELD: Revolutionizing Canine Lung Cancer Treatment The Need: Lung cancer in canines poses significant clinical challenges, mirroring the complexities of human lung cancer in non-smokers. With limited standard treatments beyond surgery, there's an urgent demand for advanced methods to assess, c…
  • College: College of Veterinary Medicine
  • Inventors: Lorch, Gwendolen
  • Licensing Officer: Dahlman, Jason "Jay"

Tomato Lines Resistant to Bacterial Spot (Rx-3, Xv3, QTL-11), Verticillium (Ve), and Fusarium (I)
TS-065858 — The Need: In the modern agricultural landscape, tomato crops face significant threats from bacterial spot, Verticillium, and Fusarium, leading to substantial yield losses and economic strain for growers. Addressing these challenges is crucial to ensure a sustainable and profitable tomato industry. …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Francis, David
  • Licensing Officer: Dahlman, Jason "Jay"

Revolutionizing Literacy Instruction with LetterWorks: Bridging Tradition and Technology
TS-065840 — The Need Incorporating Information and Communication Technologies (ICTs) into literacy instruction is imperative, especially for at-risk populations, yet research in this area remains limited. The demand for effective tools to enhance literacy learning among struggling readers is critical. Teachers…
  • College: College of Education & Human Ecology
  • Inventors: Rodgers, Emily; D'Agostino, Jerome
  • Licensing Officer: Dahlman, Jason "Jay"

Advancing Inclusive Education: Introducing the Student Evaluation of Inclusive Classroom Instruction
TS-065826 — The Need In higher education, fostering inclusive and culturally responsive classroom environments is imperative to address institutional racism and ensure equitable learning experiences for all students. To achieve this, instructors must demonstrate cultural sensitivity, responsiveness to individu…
  • College: College of Education & Human Ecology
  • Inventors: Arnold, Noelle; Luthy, Nicole; Penn, Carlotta; Pratt, Keeley
  • Licensing Officer: Dahlman, Jason "Jay"

IDEAS: Revolutionizing Early Childhood Education with Automated Interaction Analysis
TS-065825 — The Need: In early childhood education settings, understanding children's interactions, both social and linguistic, is paramount for effective teaching and development monitoring. However, manual observation and analysis of these interactions can be time-consuming and subjective, hindering educa…
  • College: College of Education & Human Ecology
  • Inventors: Gonzalez Villasanti, Hugo "Hugo"; Justice, Laura
  • Licensing Officer: Dahlman, Jason "Jay"

Clearinghouse for Evidence-based Programs and Practices for School and School District Improvement
TS-065824 — The Need: In today's educational landscape, the demand for evidence-based practices to enhance student outcomes is paramount. Educators seek efficient, accessible resources aligned with federal guidelines to drive improvement efforts effectively. However, navigating through the plethora of infor…
  • College: John Glenn College of Public Affairs
  • Inventors: Joyce, Erin; Knighton, Ryan; Maurer, Julie; Porter, Lauren
  • Licensing Officer: Dahlman, Jason "Jay"

Partnerships for Literacy (P4L): Bridging Communities for Enhanced Literacy
TS-065822 — The Need: In today's educational landscape, fostering meaningful partnerships between schools and families is paramount to enhancing literacy levels among students. However, many schools face challenges in creating sustained, goal-oriented engagements that develop the capacity of educators and f…
  • College: College of Education & Human Ecology
  • Inventors: Boone, Barbara; Wellman, Meredith
  • Licensing Officer: Dahlman, Jason "Jay"

Method for increasing English literacy through professional development with K-20 teachers
TS-065821 — The Need: In a rapidly evolving educational landscape, the demand for effective English language instruction in India is more pressing than ever. Yet, many educators face significant challenges in engaging students in meaningful conversations and writing exercises that align with their curriculum. T…
  • College: Newark Campus
  • Inventors: Rodgers, Adrian
  • Licensing Officer: Dahlman, Jason "Jay"

Student Success Dashboard: Transforming Education Through Data-Driven Support
TS-065820 — Ohio Student Success Dashboard: Revolutionizing Student Support The Need: Ohio and the national economy are undergoing a transformative shift, where traditional high school education no longer guarantees success in the job market. With nearly 60% of jobs requiring additional training beyond a high …
  • College: College of Education & Human Ecology
  • Inventors: Hawley, Joshua
  • Licensing Officer: Dahlman, Jason "Jay"

Novel Small-Molecule Natural Product Salt Enhancing Compounds
TS-065450 — The Need: In a world grappling with the consequences of poor dietary choices, the imperative to address the global health crisis has never been more critical. Poor diets contribute to 1 in 5 deaths globally, leading the USDA to recommend a 30% reduction in sodium levels in foods to combat this cris…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Peterson, Devin; Kokkinidou, Smaro "Smaro"; Peterson, Julie; Schwartz, Eric
  • Licensing Officer: Dahlman, Jason "Jay"

Reservoir Computing Optimization: Meeting the Demand for Efficient Network Topologies
TS-065449 — The Need: Modern computational tasks demand efficient and resource-effective solutions. Traditional methods often fall short due to their high resource consumption and power requirements. Reservoir computing, while promising, has faced limitations in optimizing network topologies efficiently, hinder…
  • College: College of Arts & Sciences
  • Inventors: Griffith, Aaron; Gauthier, Daniel
  • Licensing Officer: Dahlman, Jason "Jay"

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