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Isolation of an Ohio Porcine Epidemic Diarrhea Virus (PEDV) PC22A Strain in Cell Culture
TS-046905 — Porcine epidemic diarrhea virus (PEDV) has historically been an exotic disease to the U.S.. As of May, 2013, the virus made its way from China to the U.S.. This virus causes nearly 100% mortality in piglets and ranges from 80-90% morbidity. There is currently no PEDV vaccine in production. This inve…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Saif, Linda; Oka, Tomoichiro; Wang, Qiuhong
  • Licensing Officer: Dahlman, Jason "Jay"

Method to improve natural rubber (hevea/guayule)-toughened poly-(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV) for food packaging applications
TS-044688 — Nearly all plastics that are used to produce packaging materials are petroleum-based and non-biodegradable. This makes their use undesirable to consumers in an increasingly sustainability-focused market. Therefore, the development of biologically-derived, biodegradable plastic for packaging materi…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Vodovotz, Yael; Cornish, Katrina; Koelling, Kurt; Venoor, Varun "varun"; Zhao, Xiaoying "Xiaoying"
  • Licensing Officer: Dahlman, Jason "Jay"

Isolation of Porcine Epidemic Diarrhea Virus (PEDV) strain Iowa106
TS-044567 — Porcine epidemic diarrhea virus (PEDV) appeared in the US in 2013 and has spread rapidly throughout North America. The virus causes gastroenteric disease in adults and is fatal to nursing piglets, whose only protection from the disease is via passive immunity from their mother. Currently, most US …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Wang, Qiuhong; Oka, Tomoichiro; Saif, Linda
  • Licensing Officer: Dahlman, Jason "Jay"

Antimicrobials to Control Campylobacter
TS-044474 — Campylobacter is a leading cause of foodborne disease in humans, affecting more than one million Americans each year. Campylobacteriosis is projected to remain one of the most-frequent causes of disease and death worldwide. Human infection primarily occurs by ingesting contaminated chicken, and tr…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Acuna, Ulyana Munoz; Antwi, Janet; Carcache de Blanco, Esperanza; Fuchs, James; Kumar, Anand; Nislow, Corey; Pascall, Melvin
  • Licensing Officer: Dahlman, Jason "Jay"

Antimicrobials to Control Campylobacter
TS-044474 — Campylobacter is a leading cause of foodborne disease in humans, affecting more than one million Americans each year. Campylobacteriosis is projected to remain one of the most-frequent causes of disease and death worldwide. Human infection primarily occurs by ingesting contaminated chicken, and tr…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Acuna, Ulyana Munoz; Antwi, Janet; Carcache de Blanco, Esperanza; Fuchs, James; Kumar, Anand; Nislow, Corey; Pascall, Melvin
  • Licensing Officer: Dahlman, Jason "Jay"

Antimicrobials to Control Campylobacter
TS-044474 — Campylobacter is a leading cause of foodborne disease in humans, affecting more than one million Americans each year. Campylobacteriosis is projected to remain one of the most-frequent causes of disease and death worldwide. Human infection primarily occurs by ingesting contaminated chicken, and tr…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Acuna, Ulyana Munoz; Antwi, Janet; Carcache de Blanco, Esperanza; Fuchs, James; Kumar, Anand; Nislow, Corey; Pascall, Melvin
  • Licensing Officer: Dahlman, Jason "Jay"

Translational Activators of the Glutamate Transporter EAAT2 to Treat Neurological and Psychiatric Diseases
TS-043938 — Small molecule technology with novel translational activation mechanism.
Glutamate is a major neurotransmitter in the mammalian central nervous system (CNS) and essential for normal brain function including cognition, memory, and learning. However, the extracellular concentration of glutamate must remain below excitotoxic levels (~ 1 μM) to avoid overstimulation of …
  • College: College of Medicine (COM)
  • Inventors: Lin, Chien-Liang; Hodgetts, Kevin
  • Licensing Officer: Dahlman, Jason "Jay"

FARM: Fertilizer Application Resource Monitor
TS-041592 — FARM is a real-time mobile application that uses precipitation forecasts to guide farmers in their use of fertilizer and pesticides.
Weather forecasting is a useful tool for farmers who need to decide how best to treat their crops. Applying fertilizer or pesticide to crops, just to have the rain wash it away, results in a waste of resources. Additionally, many areas such as Ohio have regulations for fertilizer and pesticide run…
  • College: Office of Academic Affairs
  • Inventors: Wilson, Aaron
  • Licensing Officer: Dahlman, Jason "Jay"

FARM: Fertilizer Application Resource Monitor
TS-041592 — FARM is a real-time mobile application that uses precipitation forecasts to guide farmers in their use of fertilizer and pesticides.
Weather forecasting is a useful tool for farmers who need to decide how best to treat their crops. Applying fertilizer or pesticide to crops, just to have the rain wash it away, results in a waste of resources. Additionally, many areas such as Ohio have regulations for fertilizer and pesticide run…
  • College: Office of Academic Affairs
  • Inventors: Wilson, Aaron
  • Licensing Officer: Dahlman, Jason "Jay"

Methods of Pre-conditioning Patients for T-cell Therapy
TS-041497 — Recent advances in Chimeric Antigen Receptor (CAR) T-cell therapy have generated hope in treatment of diseases such as cancer and HIV/AIDS. Cytotoxic lymphodepletion preconditioning is a step included in most CAR T-cell therapies, where T-cells and “cytokine sink” cells are depleted to…
  • College: College of Veterinary Medicine
  • Inventors: Kim, Sanggu
  • Licensing Officer: Dahlman, Jason "Jay"

Small molecule modulators of Avian Pathogenic E. coli (APEC) virulence as a means to control avian collibacillosis
TS-040540 — Small molecules have been developed that have shown effective defense against Avian pathogenic Escherichia coli (APEC). These molecules can be used by itself, or with current antibiotics, which helps decrease the overall risk of bacterial antibiotic resistance.
Avian pathogenic Escherichia coli (APEC) is one of the most common poultry diseases that is characterized by a series of extra intestinal infections that effect the visceral organs of the bird. The disease affects chickens, turkeys, and other avian species, and highly reduces egg production and we…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Deblais, Loic; Kathayat, Dipak; Mohamed, Yosra
  • Licensing Officer: Dahlman, Jason "Jay"

The OSU Soil Organic Matter Calculator
TS-040136 — The Ohio State University’s Soil Organic Matter Calculator is a program that can be used to calculate future organic soil quality, greenhouse gas emissions, nitrogen fertility over short- and long-term scenarios in rder to help farmers decide more sustainable methods of agriculture.
Farmers, scientists, educators, industries and other non-profit organizations are increasing in need of a simple way to make accurate models and simulations of the environmental impact of land management choices and practices. Various different group and organizations from a wide variety of indust…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Islam, Khandakar; Grigar, Jerry; Reeder, Randall; Shedekar, Vinayak
  • Licensing Officer: Dahlman, Jason "Jay"

The FoodImage Smartphone App
TS-040080 — FoodImage quantifies food waste in near real-time using images of food products and food waste captured by end users or consumers.
Americans throw away approximately 80 billion pounds of food per year. However, in a study conducted by The Ohio State University, 53% of respondents indicated that food waste is a problem. A potential method to reduce food waste and its negative affects would be to increase awareness of the probl…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Roe, Brian; Apolzan, John; Martin, Corby
  • Licensing Officer: Dahlman, Jason "Jay"

Small molecule growth inhibitors of avian pathogenic E. coli (APEC) as a means to control APEC infections in poultry.
TS-039568 — Small molecules have been developed that have shown effective defense against Avian pathogenic Escherichia coli (APEC). These molecules can be used by itself, or with current antibiotics, which helps decrease the overall risk of bacterial antibiotic resistance.
Avian pathogenic Escherichia coli (APEC) is one of the most common poultry diseases that is characterized by a series of extra intestinal infections that effect the visceral organs of the bird. The disease affects chickens, turkeys, and other avian species, and highly reduces egg production and we…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Deblais, Loic; Kathayat, Dipak; Mohamed, Yosra
  • Licensing Officer: Dahlman, Jason "Jay"

Control of Salmonella in poultry using new generation small molecule growth inhibitors
TS-039567 — Small molecule compounds that can be used to inhibit Salmonella growth for safe and sustainable poultry production.
Non-typhoidal Salmonella are among the top five intestinal pathogens in the United States. Among foodborne illnesses, they are responsible for 11% of illnesses, 35% of those hospitalizations, and 28% deaths, with an estimated cost of $3.6 billion in 2014. Poultry is the most common source of wide-…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Deblais, Loic; Kathayat, Dipak; Miller, Sally; Mohamed, Yosra
  • Licensing Officer: Dahlman, Jason "Jay"

Mucoadhesive Nanoparticle Entrapped Influenza Virus Vaccine Delivery System
TS-038882 — A mucoadhesive nonoparticle entrapped influenza virus vaccine delivery system for animals and humans.
As one of the top three swine respiratory health problems in the U.S., swine influenza virus (SIV) is a key concern for the industry. SIV – referred to as “swine flu” or “flu” – can be caused by a number of different swine influenza strains. SIV has evolved from…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Gourapura, Renukaradhya; Dhakal, Santosh; Renu, Sankar
  • Licensing Officer: Dahlman, Jason "Jay"

Composition and oral delivery of nanoparticle based Salmonella vaccine for poultry
TS-038337 — A Salmonella oral vaccine to provide mucosal immunity and reduce bacterial shedding in poultry.
Fifteen of every 100,000 people will contract salmonellosis annually in the United States, with a related cost of $3.6 million in economic and medical expenses. A single outbreak can quickly increase these costs - Alamosa, CO paid over $2.6 million in 2008 following an outbreak. The disease comes …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Gourapura, Renukaradhya; Renu, Sankar; Selvaraj, Ramesh
  • Licensing Officer: Dahlman, Jason "Jay"

OSU Canaan Fir; Abies balsamea var. phanerolepis; fir tree
TS-038235 — Relatively frost resistant Canaan fir tree.
Canaan fir (Abies balsamea var phanerolepis) tree variety with a provenance of Canaan Valley, West Virginia. James Brown (Ohio State University, School of Environment and Natural Resources) sorted out the five natural seed sources (provenances) of this tree. The provenances are all found in West Vir…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Brown, James
  • Licensing Officer: Dahlman, Jason "Jay"

OH04-264-58; Triticum Aestivum; Winter Wheat
TS-038234 — OH04-264-58 is a soft wheat with very strong gluten and stability over a variety of environments.
OH04-264-58 is a soft wheat with very strong gluten developed at The Ohio State University's Ohio Agricultural Research and Development Center. Current analyses indicate that the gluten strength of OH04-264-58 is similar to that of Pioneer 25R26 and shows stability in multiple environments. Its …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Sneller, Clay
  • Licensing Officer: Dahlman, Jason "Jay"

OH7530; Solanum lycopersicum; tomato
TS-038132 — A new breed of tomatoes.
OH7530 was coded as F02-7530 in September 2002. OH7530 is derived from SG01-3008 a family with coupling-phase recombination for the Pto gene and the Rx-3 locus conferring resistance to Pseudomonas syringae pv. tomato and Xanthomonas euvesicatoria race T1, respectively, and described (Yang and Franci…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Francis, David; Aldrich, Troy
  • Licensing Officer: Dahlman, Jason "Jay"

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