TS-048073 — In functional genomic experiments to support maize breeding programs, it is difficult to understand the function of an individual gene due to that gene’s interaction with other molecular features. Furthermore, while it is possible to target multiple genes in genomic experiments, it is not fr…

TS-046905 — Porcine epidemic diarrhea virus (PEDV) has historically been an exotic disease to the U.S.. As of May, 2013, the virus made its way from China to the U.S.. This virus causes nearly 100% mortality in piglets and ranges from 80-90% morbidity. There is currently no PEDV vaccine in production. This inve…

TS-046029 — Next-generation agricultural sensor technology enables precise, data-based decision-making to be implemented at the farm level. Field operations data such as granular fertilizer application rates are useful to the producer, because optimization of nutrient supplementation increases use efficiency …

TS-045681 — Cas9-derived constructs can be used to modulate gene expression, but physical limitations restrict the application of this technique. Researchers at The Ohio State University have overcome this obstacle by engineering new Cas9-derived transcription factors.

TS-045448 — Maximized mRNA lifespan and translation for mRNA-based therapy applications.

TS-045426 — The central mission of cancer immunotherapy treatments is to aid the immune system in detecting and degrading cancer cells. For twenty years, the use of monoclonal antibodies (mAbs) as anti-tumor drugs has been successful in managing cancer disease and increasing patient lifespan. These treatments…

TS-044688 — Nearly all plastics that are used to produce packaging materials are petroleum-based and non-biodegradable. This makes their use undesirable to consumers in an increasingly sustainability-focused market. Therefore, the development of biologically-derived, biodegradable plastic for packaging materi…

TS-044567 — Porcine epidemic diarrhea virus (PEDV) appeared in the US in 2013 and has spread rapidly throughout North America. The virus causes gastroenteric disease in adults and is fatal to nursing piglets, whose only protection from the disease is via passive immunity from their mother. Currently, most US …

TS-044474 — Campylobacter is a leading cause of foodborne disease in humans, affecting more than one million Americans each year. Campylobacteriosis is projected to remain one of the most-frequent causes of disease and death worldwide. Human infection primarily occurs by ingesting contaminated chicken, and tr…

TS-044084 — Trypanosoma cruzi is a protozoan parasite that causes Chagas disease, a PRV-eligible disease that is the leading cause of heart failure in Latin America. Due to migration of infected hosts from endemic regions, Chagas disease is also a growing public health concern in the USA and other migrant des…

TS-043938 — Small molecule technology with novel translational activation mechanism.

TS-043819 — Compositions and methods for analyzing multiple biomarkers without damaging tissue.

TS-041592 — FARM is a real-time mobile application that uses precipitation forecasts to guide farmers in their use of fertilizer and pesticides.

TS-041497 — Recent advances in Chimeric Antigen Receptor (CAR) T-cell therapy have generated hope in treatment of diseases such as cancer and HIV/AIDS. Cytotoxic lymphodepletion preconditioning is a step included in most CAR T-cell therapies, where T-cells and “cytokine sink” cells are depleted to…

TS-040540 — Small molecules have been developed that have shown effective defense against Avian pathogenic Escherichia coli (APEC). These molecules can be used by itself, or with current antibiotics, which helps decrease the overall risk of bacterial antibiotic resistance.

TS-040136 — The Ohio State University’s Soil Organic Matter Calculator is a program that can be used to calculate future organic soil quality, greenhouse gas emissions, nitrogen fertility over short- and long-term scenarios in rder to help farmers decide more sustainable methods of agriculture.

TS-040080 — FoodImage quantifies food waste in near real-time using images of food products and food waste captured by end users or consumers.

TS-039568 — Small molecules have been developed that have shown effective defense against Avian pathogenic Escherichia coli (APEC). These molecules can be used by itself, or with current antibiotics, which helps decrease the overall risk of bacterial antibiotic resistance.

TS-039567 — Small molecule compounds that can be used to inhibit Salmonella growth for safe and sustainable poultry production.

TS-038882 — A mucoadhesive nonoparticle entrapped influenza virus vaccine delivery system for animals and humans.