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Methods for Making Three Dimensional Microfluidic Bioreactor Array
TS-037642 — Design for a three-dimensional microfluidic bioreactor array; device allows for culturing of a variety of cell types without contamination.
Cell culture in a three-dimensional fluidic-flow microenvironment is critical for long-term cell-based assays. Conducting in vitro research offers an accessible, reproducible, and reliable mode of investigation for therapeutic decisions before work is conducted in vivo. However, because of the com…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Wen, Yuan
  • Licensing Officer: Paschall, Christopher

Functionalization of Polymethylmethacrylate (PMMA) Surface by Amination with Polyethyleneimine (PEI) for Applications in Microfluidic Immunoassays, Protein/Enzyme Biochips, and Biocatalysis
TS-037631 — Polymethylmethacrylate (PMMA) is a useful material for development of assays, biochips, and other biological materials. However, PMMA makes for a difficult substrate because of complexities with respect to adhesion. This technology presents two new methods for enhanced protein binding onto PMMA.
Polymethylmethacrylate (PMMA) is a synthetic resin in the acrylic family, often used as a substitute for glass or as a material for biomedical devices. PMMA-based biosensors have low protein binding efficiency and low sensitivity. PMMA is used in a variety of applications like immunoassays, biosen…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Bai, Yunling
  • Licensing Officer: Paschall, Christopher

Methods and Processes for Producing Butyrate Esters from Sugars
TS-037568 — A method and process for producing butyrate esters for use as novel biofuels.These products have a similar energy content to biobutanol, but are easier to produce.
Currently, bioethanol is the major biofuel on the market, but recently butanol has gotten attention for its potential as a transportation fuel. It has many characteristics that make it a better fuel source than ethanol: butanol has 25% more Btu per gallon, it's less evaporative/explosive with …
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"
  • Licensing Officer: Paschall, Christopher

Metabolic Engineering of Clostridium Tyrobutyricum for Butanol Production
TS-037555 — A new strain of bacteria that can produce butanol at a high titer for transportation fuel.
Butanol is generally used as an industrial solvent but can also be blended with gasoline and used as transportation fuel. Butanol is commonly produced using fossil fuels, but it can also be produced from biomass, referred to as biobutanol. Biobutanol is produced from fermentation of the same feeds…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Yu, Mingrui
  • Licensing Officer: Paschall, Christopher

N-Proanol and Propionic Acid Producing Propionibacteria
TS-037515 — New method of producing n-propanol and propionic acid using a metabolically engineered propionibacteria.
Propionibacteria are well-known for their various industrial applications including the manufacturing of Swiss cheese, vitamin B12, and propionic acid. However, not much is known about their genetics, and few studies have been conducted utilizing them for metabolic engineering, mostly in vitamin B…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Ammar, Ehab
  • Licensing Officer: Paschall, Christopher

Carbon Dioxide Assisted Processing and Bonding of Polymer and Polymer Composites
TS-037400 — A novel method to bond polymer composites without the use of heat or organic solvents.
Application of either heat or organic solvents is critical to convert solid materials to fluids. For many applications, particularly biomedical products, high temperature and organic solvents may denature critical biomolecules. Residue of organic solvents may also cause severe contamination. In ad…
  • College: College of Engineering (COE)
  • Inventors: Lee, L; Tomasko, David; Yang, Yong; Zeng, Changchun
  • Licensing Officer: Wohlgamuth, Christopher

2 Stage Hybrid Membrane Process for CO2 Capture from Flue Gas in Power Plants
TS-037391 — A 2-stage enriching cascade membrane process for capturing CO2 from flue gas in a power plant without air sweep
Post-combustion carbon capture (PCC) provides an option to mitigate CO2 emissions from large stationary sources, followed by compression, transport, and geological sequestration; the captured CO2 may be used for enhanced oil recovery. Because of the system compactness and energy efficiency, CO2-se…
  • College: College of Engineering (COE)
  • Inventors: Ho, W.S. Winston; Han, Yang
  • Licensing Officer: Gooray, Arthur "Art"

CO2 Reduction to Acetate on Mixed Metal Oxide Catalyst
TS-037385 — A process for photoelectrochemical reduction of carbon dioxide to acetate using mixed metal oxide as catalysts
The combustion of fossil fuels produces billions of tons of carbon dioxide annually. Research indicates that greater concentrations of carbon dioxide in the atmosphere has altered Earth's climate, changed the pH of the ocean, and causing other potentially damaging evironmental effects. Countri…
  • College: College of Arts & Sciences
  • Inventors: Baker, Lawrence "Robert"; Yang, Xin
  • Licensing Officer: Wohlgamuth, Christopher

Amine-Containing Membranes Incorporated with Carbon Nanotubes or CO2 Separation
TS-037297 — A novel amine-containing membrane incorporated with carbon nanotubes for CO2/N2 separation with a vacuum pulled on the permeate side
CO2 concentration in the atmosphere has surpassed 400 ppm in the past decade. The combustion of fossil fuels is a major contributor to the large amount of CO2 emission, and membrane technologies have been suggested as a promising approach to capture CO2 from large stationary sources (e.g., flue ga…
  • College: College of Engineering (COE)
  • Inventors: Ho, W.S. Winston; Han, Yang
  • Licensing Officer: Gooray, Arthur "Art"

Economical Two-Stage Membrane Process for CO2 Capture from Flue Gas of Power Plants
TS-015275 — A portfolio of technologies and methods for CO2 capture that does not require complex or prohibitively large components.
There has been growing concern about global warming since the CO2 concentration in the atmosphere has surpassed 400 ppm in the past decade. The combustion of fossil fuels is one of the major contributors to the large amount of CO2 emission, and membrane technologies have been suggested as a promis…
  • College: College of Engineering (COE)
  • Inventors: Ho, W.S. Winston; Han, Yang
  • Licensing Officer: Gooray, Arthur "Art"

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