Botanical-Inspired Compounds for Mosquito Control and Resistance Management
TS-074949 —
Mosquito‑borne diseases such as dengue, Zika, chikungunya, and yellow fever remain major global health threats, however widespread resistance has eroded the effectiveness of existing insecticides. mosquito control agents for public health, vector control programs, and integrated pest management …
- College: College of Pharmacy (COP)
- Inventors: Rakotondraibe, Harinantenaina Liva; Piermarini, Peter
- Licensing Officer: Panic, Ana
Self-Regulating Platform for Drug-Eluting Medical Meshes
TS-074223 — Researchers at The Ohio State University have developed a self‑regulating manufacturing platform for porous polymer meshes that integrates mesh formation and drug loading in a single step, enabling controlled local delivery from implantable materials.
Technology Overview
Implantable meshes and porous polymer films are widely used in surgical, regenerative, and device‑based applications, but current products often separate structural support from drug delivery functions. This platform uses a reaction‑diffusion‑driven process to form poro…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Puskas, Judit; Polyak, Peter
- Licensing Officer: Panic, Ana
A new modular format for bispecific antibody fragments
TS-068425 — Functionalization of scFvs with cyclic peptide linkers
The Need
The high specificity of antibodies has been utilized to develop numerous technologies, tools and therapeutics, like ADCs and radiopharmaceuticals. Engineered antibody fragments like single-chain variable fragments (scFvs) are starting to see their way into the clinic in BiTEs and CAR T. Sc…
- College: College of Arts and Sciences (COAAS)
- Inventors: Magliery, Thomas; Do, Jamie; Han, Jeong Min "Mina"; Zhu, Ian
- Licensing Officer: Panic, Ana
Noninvasive Rapid Radiation Exposure Assay
TS-068290 — The Need
Radiation exposure poses significant health risks, including cancer and other illnesses, making it crucial for clinicians to accurately measure and assess the extent of radiation exposure. Existing methods often require invasive procedures and may not detect exposure at lower dose ranges.
…
- College: College of Arts and Sciences (COAAS)
- Inventors: Schultz, Zachary; Jacob, Naduparambil; Morder, Courtney; Witte, Spencer
- Licensing Officer: Panic, Ana
Precision RNA-PROTACs: Revolutionizing Therapeutic Targeting of Dysregulated Ribonucleoprotein Complexes
TS-065457 — The Need:
In the realm of therapeutic development, there's a pressing need for precise targeting of dysregulated ribonucleoprotein (RNP) complexes to combat various diseases, particularly neurodegenerative disorders like ALS, Alzheimer’s, and Huntington’s diseases. Traditional metho…
- College: College of Arts and Sciences (COAAS)
- Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"; Strong, Rebekah
- Licensing Officer: Panic, Ana
Magnetic Nanoparticles for Cancer Cell Classification
TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year.
The Need
Developing drugs for cance…
- College: College of Arts and Sciences (COAAS)
- Inventors: Schultz, Zachary; Rist, David; Skardal, Aleksander; Venere, Monica
- Licensing Officer: Panic, Ana
A new diagnostic assay for classic galactosemia
TS-064133 — Classic galactosemia is a genetic condition that can lead to life-threatening complications, including feeding problems, failure to thrive, liver damage, bleeding, and sepsis. If a lactose-restricted diet is provided during the first ten days of life, the neonatal symptoms quickly resolve and reduce…
- College: College of Arts and Sciences (COAAS)
- Inventors: Gopalan, Venkat; Bashian, Eleanor; Thirugnanasambantham, Pankajavalli
- Licensing Officer: Panic, Ana
Methods and Apparatus to Improve MRI Efficiency
TS-062627 — Magnetic Resonance Imaging (“MRI”) is one of the most important modern medical imaging modalities. It has far less risk of side effects than most other imaging modalities. Generally, a high quality image requires high signal-to-noise ratio, high contrast between normal and pathological t…
- College: College of Arts and Sciences (COAAS)
- Inventors: Wang, Jinghua
- Licensing Officer: Panic, Ana
Sensor for detecting Viruses
TS-062553 — The Need
The swift and accurate diagnosis of COVID-19 and other viruses is crucial in preventing their spread. Current detection methods like PCR and antibody testing have limitations, including long run times, sample preparation, and high false negative rates. Moreover, with the rapid mutation and…
- College: College of Arts and Sciences (COAAS)
- Inventors: Schultz, Zachary; Payne, Taylor
- Licensing Officer: Panic, Ana
Collaborative Interaction System- Wearable Technology for Collaborative Interaction for Children with Disabilities
TS-062336 — The Need: Enhancing Collaborative Interaction for Children with Disabilities
Millions of children in the United States with physical or cognitive disabilities face challenges in participating fully in play and forming meaningful connections with their parents and caregivers. The lack of touch and c…
- College: College of Arts and Sciences (COAAS)
- Inventors: Swearingen, EunKyoung "Kyoung"; Kiourti, Asimina; Swearingen, Scott; Thrane, Susan
- Licensing Officer: Panic, Ana
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