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Precision RNA-PROTACs: Revolutionizing Therapeutic Targeting of Dysregulated Ribonucleoprotein Complexes
TS-065457 — The Need: In the realm of therapeutic development, there's a pressing need for precise targeting of dysregulated ribonucleoprotein (RNP) complexes to combat various diseases, particularly neurodegenerative disorders like ALS, Alzheimer’s, and Huntington’s diseases. Traditional metho…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"; Strong, Rebekah
  • Licensing Officer: Panic, Ana

Methods and Apparatus to Improve MRI Efficiency
TS-062627 — Magnetic Resonance Imaging (“MRI”) is one of the most important modern medical imaging modalities. It has far less risk of side effects than most other imaging modalities. Generally, a high quality image requires high signal-to-noise ratio, high contrast between normal and pathological t…
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua
  • Licensing Officer: Panic, Ana

SCTaware: Empowering Health Equity through Virtual Sickle Cell Trait Education
TS-062440 — The Need: Sickle Cell Trait (SCT) affects a significant portion of the population, posing a pressing public health concern. Lack of awareness and limited access to understandable information about SCT's reproductive implications contribute to health disparities among affected individuals. In-per…
  • College: College of Arts & Sciences
  • Inventors: Chan, Peter; McCorkle, Benson; Shen, Yvette
  • Licensing Officer: Panic, Ana

Collaborative Interaction System- Wearable Technology for Collaborative Interaction for Children with Disabilities
TS-062336 — The Need: Enhancing Collaborative Interaction for Children with Disabilities Millions of children in the United States with physical or cognitive disabilities face challenges in participating fully in play and forming meaningful connections with their parents and caregivers. The lack of touch and c…
  • College: College of Arts & Sciences
  • Inventors: Swearingen, EunKyoung "Kyoung"; Kiourti, Asimina; Swearingen, Scott; Thrane, Susan
  • Licensing Officer: Panic, Ana

Stealth liposomes with greater stability for improved drug delivery
TS-048888 — Liposome drug delivery systems play a significant role in the formulation of new therapies. These liposome-encapsulated drugs are used to treat a wide range of diseases such as cancer, influenza, and hepatitis. While endogenous liposomes are recognized by the mononuclear phagocyte system and clear…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis
  • Licensing Officer: Panic, Ana

Electrophiles for Re-activation of Aged Acetylcholine Esterase
TS-044619 — Organophosphorus (OP) poisons including sarin, VX, and novichoks are lethal agents of chemical warfare. Their toxicity is due to their direct inhibition of acetylcholinesterase (AChE), an enzyme that is vital to the nervous system via regulation of the neurotransmitter acetylcholine (ACh). AChE in…
  • College: College of Arts & Sciences
  • Inventors: Hadad, Christopher; Callam, Christopher; Corrigan, Thomas; Dicken, Rachel; Dogan Ekici, Ozlem; Fitzpatrick, Keegan; Franjesevic, Andrew; McElroy, Craig; McKenney, Ryan; Muthukrishnan, Siva; Sanan, Toby; Vyas, Shubham; Yoder, Ryan; Young, Amneh "Amneh"
  • Licensing Officer: Panic, Ana

Method to Synthesize Ceratamine A and B and Analogs Thereof
TS-030264 — A chemical process to produce ceratamine A and B.
The natural products ceratamines A and B were isolated from a marine sponge in minute quantities and shown to have potent anti-tumor activity. Due to the insufficient sample size and subsequent lack of availability of the producing sponge, evaluation was incomplete. Thus, the clinical potential ne…
  • College: College of Arts & Sciences
  • Inventors: Coleman, Robert "Rob"; Campbell, Erica
  • Licensing Officer: Panic, Ana

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