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A Cybersecurity Vulnerability Prioritization System Including Identifying "Super-Critical" Vulnerabilities, predicting "Dark Host" Vulnerabilities, and Addressing Economic Costs
TS-066063 — Our cybersecurity vulnerability maintenance system stands as a pillar of modern security strategy, transforming reactive security measures into a preemptive defense mechanism. This integration of technology and economics ensures that your most critical assets are protected efficiently and effectively, making it an invaluable tool for any organization serious about security.
In today’s hyper-connected world, the escalation in cyber threats poses significant risks to organizational data and systems. Vulnerabilities within network infrastructures can lead to massive security breaches, as demonstrated by incidents like the 2017 Equifax hack. Effective vulnerability…
  • College: College of Engineering (COE)
  • Inventors: Allen, Theodore; Liu, Enhao
  • Licensing Officer: Zinn, Ryan

SimulationAI -- AI-Enabled Software Solution for Physics-Based Simulations
TS-066058 — By adopting our AI-driven solution, engineering teams can achieve more in less time, push the boundaries of innovation, and significantly cut down costs, all while maintaining or increasing the reliability and accuracy of their structural and material analysis. This is not just an evolution in FEM technology—it's a revolution.
In an era where precision and efficiency drive the success of engineering projects, the finite element method (FEM) remains indispensable but is burdened by high operational and computational costs. These costs often lead to overlooked uncertainty factors, suboptimal designs, and significant finan…
  • College: College of Engineering (COE)
  • Inventors: Soghrati, Soheil; vemparala, Balavignesh; Yang, Ming
  • Licensing Officer: Zinn, Ryan

Synthetic approaches for mitigating battery capacity loss in oxide anodes
TS-066056 — The Need The advancement of lithium-ion battery technology relies heavily on increasing energy density, yet practical usage of silicon (Si) anodes faces challenges due to parasitic side reactions and active lithium consumption. Controlling lithium amounts precisely while achieving uniform distribut…
  • College: College of Arts & Sciences
  • Inventors: Co, Anne; Hwang, Jisun; Lorie Lopez, Jose
  • Licensing Officer: Randhawa, Davinder

T-cells with Enhanced Ability to Respond to Exogenous Ligands
TS-066052 — Novel T-cells expressing the IL-2a receptor to enhance cancer cell targeting.
The Need As interest in cell-based therapies, particularly for cancer treatment, continues to rise, there’s a critical need for therapeutic cells capable of robust proliferation in vivo. Existing methods relying on exogenous cytokines like IL-2 face challenges due to dose-limiting toxicity an…
  • College: OSU Wexner Medical Center
  • Inventors: Rubinstein, Mark
  • Licensing Officer: Schultz, Teri

Novel Antibodies Targeting IL-2
TS-066051 — Novel antibodies targeting IL-2 with the ability to inhibit IL-2 signaling through IL-2 Rαβg to a greater extent than through IL-2 Rβg.
IL-2 and its receptor IL-2R are known to play multiple roles in shaping the immune response, including both immune activation and tolerance. Expression of intermediate-affinity IL-2 receptors by different immune cell subsets determines cellular sensitivity to IL-2. However, the dynamic interplay bet…
  • College:
  • Inventors:
  • Licensing Officer: Schultz, Teri

Anode synthesis using spray pyrolysis
TS-066037 — The Need In the realm of materials science and energy storage, there's a growing demand for innovative anode synthesis methods that yield materials with improved mechanical and electrochemical properties. Traditional synthesis techniques often fall short in achieving the desired performance met…
  • College: College of Arts & Sciences
  • Inventors: Co, Anne; Lorie Lopez, Jose
  • Licensing Officer: Randhawa, Davinder

Metal nitric oxides redox flow batteries
TS-066016 — The Need Redox flow batteries (RFBs) offer a promising solution for storing intermittent renewable energy in the electrical grid. However, their reliance on finite and unsustainable transition metals, such as vanadium, poses significant sustainability challenges. The rising costs and environmental …
  • College: College of Arts & Sciences
  • Inventors: Zhang, Shiyu; Park, Jaehyun
  • Licensing Officer: Randhawa, Davinder

Designing High-Donicity Anions for Rechargeable Potassium Superoxide/Peroxide Batteries
TS-066015 — The Need Over the past two decades, the advancement of metal-O2 batteries has been hindered by issues of instability, reversibility, and poor energy efficiency, primarily due to the instability of superoxide in the presence of Li+ and Na+ ions. Existing solutions such as Li-O2 and Na-O2 batteries h…
  • College: College of Arts & Sciences
  • Inventors: Wu, Yiying
  • Licensing Officer: Randhawa, Davinder

Gene Therapy Approach for Treating Neuropathy
TS-065913 — Gene therapy strategies for treating peripheral neuropathy.
Peripheral neuropathy (PN) results in loss of innervation by the peripheral nerves in tissues such as skin, muscle, heart, and adipose tissue. It is a painful, debilitating disease, that is estimated to affect between 20 and 30 million Americans. The number of Americans affected by PN is likely muc…
  • College: College of Medicine (COM)
  • Inventors: Townsend, Kristy; Blaszkiewicz, Magdalena; Cao, Lei
  • Licensing Officer: Schultz, Teri

System for automated high-speed imaging and genetic manipulation of C. elegans on agar media
TS-065892 — The Need The microscopic worm C. elegans is a model animal studied in more than 1500 biological and medical research laboratories worldwide due to its genetic manipulability and optical transparency. In C. elegans research, the manual process of picking worms between plates presents a significant …
  • College: College of Engineering (COE)
  • Inventors: Fang-Yen, Christopher "Chris"; Alhalbi, Serge; Li, Zihao
  • Licensing Officer: Randhawa, Davinder

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