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Methods to improve the jitter and time walk of integrated constant fraction discriminators
TS-064826 — The Need Accurate measurements of energy and time-of-arrival of photons, particles, or ionizing radiation are crucial for identifying individual particles and enhancing spatial and temporal resolution in various systems. Technologies such as Light Detection and Ranging (LiDAR), positron emission to…
  • College: College of Arts & Sciences
  • Inventors: Kagan, Harris; Abusareya, Mo'men; Khalil, Waleed; Smith, Dale "Shane"
  • Licensing Officer: Dahlman, Jason "Jay"

Advanced AAV Gene Therapy Characterization Technique
TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …
  • College: College of Arts & Sciences
  • Inventors: Wysocki, Vicki; Cleary, Sean; Du, Chen
  • Licensing Officer: Dahlman, Jason "Jay"

Unique Panoptic Ion Source for Analyzing Complex Mixtures with Mass Spectroscopy
TS-062577 — Mass spectrometry (MS) is a widely used research tool for determining the exact molecular weight of particles within a sample. It separates electrically charged ions within a gas phase that are subsequently transferred into a mass analyzer, where they are sorted in space or time according to their m…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Amoah, Enoch; Chintalapudi, Kavyasree "Kavya"; Kulyk, Dmytro
  • Licensing Officer: Panic, Ana

Ion Carpet-Based Surface-Induced Dissociation Device
TS-062342 — The Need In the field of mass spectrometry (MS), the study of proteins and protein complexes in their native form, known as native MS, has become crucial in understanding their structure and function. However, the current collision-induced dissociation (CID) technique used in tandem MS experiments …
  • College: College of Arts & Sciences
  • Inventors: Wysocki, Vicki; Gilbert, Joshua; Stiving, Alyssa
  • Licensing Officer: Dahlman, Jason "Jay"

Next-Generation Contained Mass Spectrometry capable of On-line Solid-Phase Extraction and Atmospheric Pressure Chemical Ionization of Nonvolatile Solid and Liquid Complex Samples
TS-062340 — The Need There is a commercial need for an advanced ionization and analysis technology that can effectively and rapidly detect and analyze organic compounds, including both polar and non-polar ones, in various matrices. The current challenges in existing ambient mass spectrometry (MS) methods inclu…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Kulyk, Dmytro
  • Licensing Officer: Panic, Ana

Development of Thread Spray Ambient Mass Spectrometry
TS-062337 — The Need: The healthcare industry is witnessing rapid changes, and the establishment of biobanks to collect and store biological specimens has become crucial for facilitating research and healthcare advancements. However, current microsampling techniques face challenges such as handling small sample…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Jackson, Sierra; Swiner, Devin
  • Licensing Officer: Panic, Ana

Paper-based Dried Blood Spheroids for Stabilization of Labile Organic Compounds Stored in Ambient Air
TS-038604 — Apparatus and methods to form three-dimensional dried blood spheroids on hydrophobic paper substrates.
Dried blood spots on paper substrates offer a facile sample collection, storage, and transportation approach for biofluids. However, variable diffusion, volcanic effects, analyte instability, and difficulty in recovering samples from paper plague this method, lowering confidence in analyte quantif…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Damon, Deidre
  • Licensing Officer: Panic, Ana

System for Measuring Nitric Oxide in Breath Vapor
TS-030498 — A novel system that selectively detects nitric oxide and generates a voltage indicating the measured amount.
Nitric oxide plays an important role in the biological system of living organisms. Nitiric oxide has been shown to regulate and mediate numerous processes in the nervous, immune, and cardiovascular systems by transmitting signals throughout the body. It is used within the cardiovascular system to …
  • College: College of Arts & Sciences
  • Inventors: Dutta, Prabir; Mondal, Suvra
  • Licensing Officer: Zinn, Ryan

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