Advanced AAV Gene Therapy Characterization Technique
TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …
- College: College
of
Arts
&
Sciences
- Inventors: Wysocki, Vicki; Cleary, Sean; Du, Chen
- Licensing Officer: Dahlman, Jason "Jay"
Panoptic Ion Source for Comprehensive Mass Spectrometry Analysis
TS-062577 — The Need
Traditional Mass Spectrometry (MS) methods require solid and liquid samples to be vaporized and charged before analysis, which can be limiting. Existing ion sources are often specialized for specific types of analytes, leading to inefficiencies and the need for multiple devices. There is a…
- College: College
of
Arts
&
Sciences
- Inventors: Badu-Tawiah, Abraham; Amoah, Enoch; Chintalapudi, Kavyasree "Kavya"; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Unraveling Biomolecular Structures with Surface-Induced Dissociation Mass Spectrometry
TS-062550 — The Need: The need for surface-induced dissociation (SID) technology arises from the limitations of current mass spectrometric methods in studying the tertiary and quaternary structure of proteins and their complexes. While mass spectrometry is a powerful tool for structural biology, existing activa…
- College: College
of
Arts
&
Sciences
- Inventors: Wysocki, Vicki; Gilbert, Joshua; Harvey, Sophie; Jones, Benjamin; Stiving, Alyssa; VanAernum, Zachary "Zac"
- Licensing Officer: Panic, Ana
Ion Carpet-Based Surface-Induced Dissociation Device
TS-062342 — The Need
In the field of mass spectrometry (MS), the study of proteins and protein complexes in their native form, known as native MS, has become crucial in understanding their structure and function. However, the current collision-induced dissociation (CID) technique used in tandem MS experiments …
- College: College
of
Arts
&
Sciences
- Inventors: Wysocki, Vicki; Gilbert, Joshua; Stiving, Alyssa
- Licensing Officer: Dahlman, Jason "Jay"
Thread-Based Immunoassay and Mass Spectrometry for Disease Biomarker Detection
TS-062337 — Background:
Current immunoassay methods often rely on magnetic beads for sample collection and signal amplification, typically employing colorimetric detection based on enzymatic reactions. This approach raises stability concerns and is not ideal for field analysis due to the necessity of lasers fo…
- College: College
of
Arts
&
Sciences
- Inventors: Badu-Tawiah, Abraham; Jackson, Sierra; Swiner, Devin
- Licensing Officer: Panic, Ana
Paper-based Dried Blood Spheroids for Stabilization of Labile Organic Compounds Stored in Ambient Air
TS-038604 — Apparatus and methods to form three-dimensional dried blood spheroids on hydrophobic paper substrates.
Dried blood spots on paper substrates offer a facile sample collection, storage, and transportation approach for biofluids. However, variable diffusion, volcanic effects, analyte instability, and difficulty in recovering samples from paper plague this method, lowering confidence in analyte quantif…
- College: College
of
Arts
&
Sciences
- Inventors: Badu-Tawiah, Abraham; Damon, Deidre
- Licensing Officer: Panic, Ana