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Free Energy Spectroscopy: Transforming Molecular Analytics for Next-Generation Biotech and Pharma
TS-071946 — Powering faster, smarter decisions with real-time molecular insights for research and therapeutic development.
Overview Pharmaceutical and biotech companies often face delays and uncertainty in new drug development due to insufficient experimental insight into the shifting behaviors of large biomolecular complexes— processes critical to understanding disease and drug mechanisms. Free Energy Spectrosco…
  • College: College of Arts & Sciences
  • Inventors: Poirier, Michael; Bonin, Kalven; Bundschuh, Ralf; Castro, Carlos
  • Licensing Officer: Panic, Ana

Instant Diagnostics, Anywhere
TS-070543 — A Platform for High-Throughput Biomarker Detection that is portable, fast, and requires minimal sample
The Need The diagnostics market is under increasing pressure to deliver faster, more reliable, and less invasive solutions, driven by growing global health challenges. Current technologies face critical limitations, including large sample requirements, labor-intensive workflows, and reliance on exp…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Seth, Ayesha; Zerrudo, Stephanee
  • Licensing Officer: Panic, Ana

Magnetic Nanoparticles for Cancer Cell Classification
TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year. The Need Developing drugs for cance…
  • College: College of Arts & Sciences
  • Inventors: Schultz, Zachary; Rist, David; Skardal, Aleksander; Venere, Monica
  • Licensing Officer: Panic, Ana

Unveiling Biochemically Responsive MR Probes for Precision Beyond Limits
TS-064179 — In the realm of medical diagnostics, the need for precise and non-invasive detection of molecular-level pathology has been a longstanding challenge. Traditional imaging techniques often fall short in providing detailed insights into biological processes at this scale. To address this gap, there is…
  • College: College of Arts & Sciences
  • Inventors: Shafaat, Hannah "Hannah"
  • Licensing Officer: Dahlman, Jason "Jay"

A new diagnostic assay for classic galactosemia
TS-064133 — Classic galactosemia is a genetic condition that can lead to life-threatening complications, including feeding problems, failure to thrive, liver damage, bleeding, and sepsis. If a lactose-restricted diet is provided during the first ten days of life, the neonatal symptoms quickly resolve and reduce…
  • College: College of Arts & Sciences
  • Inventors: Gopalan, Venkat; Bashian, Eleanor; Thirugnanasambantham, Pankajavalli
  • Licensing Officer: Panic, Ana

Network-based Approach for Accurate Brain Modeling
TS-062628 — More than a billion people worldwide suffer from some neurological disorders, such as Alzheimer's, Parkinson's, multiple sclerosis, epilepsy, stroke, autism, addiction, and many others. These conditions result in more than 7 million deaths, with associated costs exceeding $1.5 trillion annua…
  • College: College of Arts & Sciences
  • Inventors: Cranmer, Skyler; Bhamidi, Shankar; Denny, Mathew; Desmarais, Bruce; Lu, Zhong-Lin; Stillman, Paul; Wilson, James
  • Licensing Officer: Dahlman, Jason "Jay"

Methods and Apparatus to Improve MRI Efficiency
TS-062627 — Magnetic Resonance Imaging (“MRI”) is one of the most important modern medical imaging modalities. It has far less risk of side effects than most other imaging modalities. Generally, a high quality image requires high signal-to-noise ratio, high contrast between normal and pathological t…
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua
  • Licensing Officer: Panic, Ana

Tunable Fingerloop DNA antisense motifs for nucleic acid targeting and detection technologies
TS-062555 — The Need: Improved Nucleic Acid Detection Probes There is a growing need for advanced detection probes that can effectively identify target nucleic acid sequences while reducing binding to mismatched targets. Existing technologies often suffer from false positive results due to temperature fluctuat…
  • College: College of Arts & Sciences
  • Inventors: Lease, Richard
  • Licensing Officer: Dahlman, Jason "Jay"

Sensor for detecting Viruses
TS-062553 — The Need The swift and accurate diagnosis of COVID-19 and other viruses is crucial in preventing their spread. Current detection methods like PCR and antibody testing have limitations, including long run times, sample preparation, and high false negative rates. Moreover, with the rapid mutation and…
  • College: College of Arts & Sciences
  • Inventors: Schultz, Zachary; Payne, Taylor
  • Licensing Officer: Panic, Ana

Functional "fingerloop" DNA antisense motifs for nucleic acid targeting and detection technologies
TS-062547 — The Need: The field of molecular biology and genetic engineering faces challenges in achieving precise and accurate detection and amplification of target nucleic acid sequences. Traditional hybridization technologies suffer from the issue of mismatched targets, leading to reduced specificity and rel…
  • College: College of Arts & Sciences
  • Inventors: Lease, Richard
  • Licensing Officer: Dahlman, Jason "Jay"

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