TS-068275 — The small molecule inhibitor targets methanogenic archaea in the rumen, offering a novel and sustainable solution to significantly reduce methane emissions from ruminants. Background Atmospheric methane levels have doubled over the past century, driven largely by emissions from ruminant…

TS-065394 — The Need: Salmonella Dublin (S. Dublin) is of concern in the cattlepopulation. The current detection methods, particularly culture-based techniques are time-consuming and lack sensitivity in environmental samples. As a result, treatment effective surveillance and epidemiological understanding is hin…

TS-062364 — The Need: Addressing the Threat of African Swine Fever Virus (ASF) African swine fever (ASF) presents a severe commercial burden given the highly contagious and deadly nature of the viral disease. With no existing treatment or vaccine available, ASF outbreaks have devastated domestic and feral pig …

TS-062229 — The Need Avian pathogenic Escherichia coli (APEC) and Salmonella infections in poultry pose a significant commercial and health challenge. Current treatments relying on antimicrobial drugs have limited effectiveness and contribute to the emergence of antibiotic-resistant strains, exacerbating the p…

TS-062219 — The Need: Addressing the Global Threat of Necrotic Enteritis in Poultry Necrotic enteritis (NE) poses a significant commercial challenge to the poultry industry, with estimated annual costs reaching up to 5-6 billion USD worldwide. The disease, caused by Clostridium perfringens, affects broilers, l…

TS-062211 — The Need: Addressing the Limitations of Current Flu Vaccines Influenza epidemics and pandemics present significant challenges to public health and global economies. Existing flu vaccines are strain-specific, providing limited cross-protective immunity and often lack long-term effectiveness. Additio…

TS-060542 — The Problem Swine influenza is an acute respiratory disease of pigs caused by swine influenza A virus (SwIAV). Pigs are naturally vulnerable to SwIAV-associated with secondary bacterial infections and is an economic threat to the global pig industry. Commonly circulating SwIAV strains in swine popu…

TS-052320 — The Need Avian pathogenic Escherichia coli (APEC) and Salmonella infections in poultry pose a significant commercial and health challenge. Current treatments relying on antimicrobial drugs have limited effectiveness and contribute to the emergence of antibiotic-resistant strains, exacerbating the p…

TS-052242 — Mastitis is the both the most common and most expensive disease in the dairy industry. When it occurs in dairy cows, mastitis leads to deterioration in milk production and quality that causes a decrease in profitability. Therefore, early detection of bacterial infection in the udders is imperative…

TS-044474 — The Need Foodborne illnesses caused by bacterial pathogens like Campylobacter pose a significant public health concern worldwide, leading to millions of illnesses and thousands of deaths each year. Increasing bacterial resistance to antibiotics is creating an urgent need for new and novel antibioti…