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miRNA Biomarkers for Diagnosis and Prediction of Radiation Induced Injury
TS-041968 — A minimally invasive procedure to determine radiation toxicity in therapy patients or victims of nuclear accidents.
The lack of a reliable radiation biodosimeter has been a major barrier to medical decision-making regarding the triage and treatment of persons who might be at risk for developing acute radiation syndromes (ARS) following nuclear events (e.g. reactor accidents, "dirty bomb" assaults, etc…
  • College: College of Medicine (COM)
  • Inventors: Jacob, Naduparambil "Naduparambil"
  • Licensing Officer: Norris, Francis "Frank"

Amine-Containing Facilitated Transport Membranes For Carbon Dioxide/Nitrogen Separation
TS-041856 — Novel membrane technology utilizing active transport for carbon dioxide/nitrogen separation. The membrane exhibits high permeance and selectivity
Improved separation of by-product carbon dioxide from nitrogen in power plants and industrial exhaust systems would considerably decrease greenhouse gas emissions. The current method of separation that is most often used in industry is amine absorption, however this method is costly, has a large c…
  • College: College of Engineering (COE)
  • Inventors: Ho, W.S. Winston; Han, Yang
  • Licensing Officer: Gooray, Arthur "Art"

Junctional Tourniquet for Groin and Axillary Regions
TS-041808 — A tourniquet with a ratcheting lock to keep pressure on wounds in the groin and axillary regions. Hemostasis can be acheived while the patient is still in the field.
Patients with blood loss in the field need to be treated immediately to prevent ongoing blood loss, shock, and death; bleeding from extremity and junctional wounds is the leading cause of potentially preventable death from penetrating injuries. Direct manual pressure is effective for the initial c…
  • College: OSU Wexner Medical Center
  • Inventors: McElroy, James; Graham, Nadi; Nocera, Tanya
  • Licensing Officer: Flammang, Ann Marie

Nonadhesive Medical Tube Attachment Device
TS-041656 — A device that holds nasogastric tubes, oxygen nasal cannulas, and facial dressings without adhesive.
Nasogastric tubes are used to give patients food and medications. Current commercially available tube holders are adhesive devices that attach to the nose. The devices put pressure on the nose and have to be completely removed to check the skin underneath or to adjust the tubes. Oxygen nasal cannu…
  • College: OSU Wexner Medical Center
  • Inventors: Huffman, Jennifer; west, tabitha
  • Licensing Officer: Flammang, Ann Marie

FARM: Fertilizer Application Resource Monitor
TS-041592 — FARM is a real-time mobile application that uses precipitation forecasts to guide farmers in their use of fertilizer and pesticides.
Weather forecasting is a useful tool for farmers who need to decide how best to treat their crops. Applying fertilizer or pesticide to crops, just to have the rain wash it away, results in a waste of resources. Additionally, many areas such as Ohio have regulations for fertilizer and pesticide run…
  • College: Office of Academic Affairs
  • Inventors: Wilson, Aaron
  • Licensing Officer: Dahlman, Jason "Jay"

Papverine Derivatives as Metabolic Radiosensitizers
TS-041504 — Papverine derivatives that can be used as metabolic radiosensitizers. The compounds make cancer cells more sensitive to radiation therapy without the concomitant toxicity issues that can occur as a side-effect of papverine.
Radiation therapy is a common treatment for cancerous tumors. Different types of cancer cells have varying sensitivity to radiation therapy, and some are almost unaffected by treatment. For example, breast cancer, glioblastoma, bladder cancer, and soft-tissue carcinoma do not react well to radiati…
  • College: College of Medicine (COM)
  • Inventors: Denko, Nicholas; Benej, Martin; Mitton-Fry, Mark; Papandreou, Ioanna; Vibhute, Sandip
  • Licensing Officer: Paschall, Christopher

RadApp: A mobile application solution for centralized distribution of information to improve workflow, communication, networking, education, and patient safety in the healthcare setting.
TS-041197 — Medical institutions depend on accessing many sources of changing information in various different forms to be successful. Moreover, distributing this information in a concise user-friendly way for each role in the department can be difficult. In particular, this is important for busy, tertiary-le…
  • College: College of Medicine (COM)
  • Inventors: Makary, Mina; Egbert, Nitin
  • Licensing Officer: Flammang, Ann Marie

Simple tool for uniform excision and transfer of biological samples
TS-041193 — A novel tool that offers improved efficiency, convenience, and precision for excision of DNA and protein bands or biological tissues.
The use of gel electrophoresis and other similar techniques is an invaluable part of biological research and has been for several decades. A crucial point in this process is the cutting of specific bands of interest for further sequencing or experimentation. The precision and quality of these cuts…
  • College: College of Medicine (COM)
  • Inventors: Gadepalli, Venkat Sundar
  • Licensing Officer: Norris, Francis "Frank"

Method to improve efficiency and specificity of human tumor targeting and elimination by using a combination of split & splice protein toxins and oncolytic viruses
TS-040838 — Novel strategy to improve efficiency and specificity of tumor treatment via combinative use of a split & splice protein toxin and oncolytic virus.
In combating malignancies as complex as cancer, researchers and clinicians have created a diverse set of strategies to reduce tumor burden. Oncolytic viruses (OVs) have emerged as a promising means of treating this disease due to their potential to selectively target and effectively kill cancer ce…
  • College: College of Arts & Sciences
  • Inventors: Kudryashov, Dmitri; Kudryashova, Elena
  • Licensing Officer: Flammang, Ann Marie

Small molecule modulators of Avian Pathogenic E. coli (APEC) virulence as a means to control avian collibacillosis
TS-040540 — Small molecules have been developed that have shown effective defense against Avian pathogenic Escherichia coli (APEC). These molecules can be used by itself, or with current antibiotics, which helps decrease the overall risk of bacterial antibiotic resistance.
Avian pathogenic Escherichia coli (APEC) is one of the most common poultry diseases that is characterized by a series of extra intestinal infections that effect the visceral organs of the bird. The disease affects chickens, turkeys, and other avian species, and highly reduces egg production and we…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Deblais, Loic; Kathayat, Dipak; Mohamed, Yosra
  • Licensing Officer: Dahlman, Jason "Jay"

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