Innovative Biomarker Technology for Detecting and Treating Endothelial Injury in Neurological Disorders
TS-066771 —
Endothelial injury is a significant pathological mechanism underlying various neurological disorders, including neurodegenerative, neuroinflammatory, and cerebrovascular diseases. Current clinical and research settings lack reliable biomarkers to detect or measure endothelial injury in the human C…
- College: College
of
Medicine
(COM)
- Inventors: Al Tarawneh, Rawan
- Licensing Officer: Willson, Christopher
MicroRNA profile predicts colon cancer prognosis
TS-065453 — The Need:
Colon cancer remains one of the most prevalent and lethal forms of cancer worldwide. Timely and accurate diagnosis is critical for effective treatment and improved patient outcomes. Current diagnostic methods often lack the precision and sensitivity needed for early detection and prognosi…
- College: College
of
Medicine
(COM)
- Inventors: Croce, Carlo
- Licensing Officer: Schultz, Teri
Unlocking New Frontiers in Diabetic Retinopathy Detection: Introducing Vessel Orientation-Based Quantitative OCTA Technology
TS-062762 — Pinpointing previously concealed sectoral differences in the diabetic retina to diagnose DR earlier.
Diabetic Retinopathy (DR) is a leading cause of blindness globally, requiring early and accurate diagnosis for effective intervention.
The Need
Current diagnostic methods for DR lack the precision needed to identify subtle retinal microvascular changes in the disease’s early stages. There i…
- College: College
of
Medicine
(COM)
- Inventors: Ma, Yanhui
- Licensing Officer: Willson, Christopher
Enhancing Surgical Precision with Anti-TAG-72 Imaging Agents
TS-062548 — The Need: Enhancing Surgical Precision with Anti-TAG-72 Imaging Agents
Colorectal carcinoma is a significant medical challenge, with a high incidence rate in the USA. Current surgical approaches, along with external imaging technologies, have limitations in accurately detecting cancerous tissues, l…
- College: College
of
Medicine
(COM)
- Inventors: Gong, Li; Tweedle, Michael
- Licensing Officer: Willson, Christopher
MicroRNA-Based Methods and Compositions for the Diagnosis, Prognosis and Treatment of Solid Cancers
TS-062318 — The Need
Cancer is a significant health problem and a leading cause of death in developed countries. Solid cancers, including prostate, breast, lung, stomach, colon, and pancreatic cancers, pose particularly challenging diagnostic and treatment obstacles. Early detection of these cancers is crucial…
- College: College
of
Medicine
(COM)
- Inventors: Croce, Carlo; Calin, George; Volinia, Stefano
- Licensing Officer: Willson, Christopher
Diagnostics and Prognostics of Prostate Cancer
TS-062299 — The Need: Addressing Prostate Cancer Diagnostics and Therapeutics
Prostate cancer remains a significant challenge in medical diagnosis and treatment, requiring advancements in diagnostics, therapeutics, and prognostics. Current approaches fall short in providing accurate and effective solutions, le…
- College: College
of
Medicine
(COM)
- Inventors: Croce, Carlo
- Licensing Officer: Willson, Christopher
MicroRNA signatures in human ovarian cancer
TS-062298 — The Need:
Ovarian cancer remains a significant challenge in the field of
medicine, with late-stage diagnosis and limited effective treatments contributing to high mortality rates. The need for improved diagnostic tools and targeted therapies is evident to address this aggressive disease. Convention…
- College: College
of
Medicine
(COM)
- Inventors: Croce, Carlo
- Licensing Officer: Willson, Christopher
Composition and Methods for Lung Cancer Diagnosis and Treatment
TS-062296 — The Need: Advancing Lung Cancer Detection and Treatment
Lung cancer continues to be a global health concern, accounting for the highest number of cancer-related deaths worldwide. In the United States, it is the leading cause of cancer mortality for both men and women, with a disheartening five-year…
- College: College
of
Medicine
(COM)
- Inventors: Croce, Carlo; Calin, George
- Licensing Officer: Willson, Christopher
Composition and Methods for Breast Cancer Diagnosis and Treatment
TS-062295 — The Need:
Breast cancer continues to be a significant health challenge, affecting a large number of women worldwide and remaining the second leading cause of cancer-related deaths among women in the United States. Despite advancements in detection and treatment, there is no universally successful m…
- College: College
of
Medicine
(COM)
- Inventors: Croce, Carlo; Calin, George
- Licensing Officer: Willson, Christopher
Metabolite-Based Diagnostics for Joint Infection
TS-059537 — An untargeted NMR-based metabolomics approach to identify metabolic compounds as signatures
of bacterial joint infections and methods for the treatment and prevention there
of.
Pseudomonas aeruginosa, a biofilm-producing pathogenic bacterium, exhibits resistance to many antibiotics. This leads to acute and chronic joint infections that are difficult to treat. Accordingly, a critical need exists for accurate biofilm diagnosis, prevention, and treatment. While culture-free…
- College: College
of
Medicine
(COM)
- Inventors: Stoodley, Paul "DECEASED"; Bruschweiler, Rafael; Leggett, Abigail
- Licensing Officer: Hampton, Andrew
Show More Technologies