MicroRNA profile predicts colon cancer prognosis
TS-065453 — The Need:
Colon cancer remains one of the most prevalent and lethal forms of cancer worldwide. Timely and accurate diagnosis is critical for effective treatment and improved patient outcomes. Current diagnostic methods often lack the precision and sensitivity needed for early detection and prognosi…
- College: College
of
Medicine
(COM)
- Inventors: Croce, Carlo
- Licensing Officer: Schultz, Teri
Enhancing Surgical Precision with Anti-TAG-72 Imaging Agents
TS-062548 — The Need: Enhancing Surgical Precision with Anti-TAG-72 Imaging Agents
Colorectal carcinoma is a significant medical challenge, with a high incidence rate in the USA. Current surgical approaches, along with external imaging technologies, have limitations in accurately detecting cancerous tissues, l…
- College: College
of
Medicine
(COM)
- Inventors: Gong, Li; Tweedle, Michael
- Licensing Officer: Willson, Christopher
MicroRNA-Based Methods and Compositions for the Diagnosis, Prognosis and Treatment of Solid Cancers
TS-062318 — The Need
Cancer is a significant health problem and a leading cause of death in developed countries. Solid cancers, including prostate, breast, lung, stomach, colon, and pancreatic cancers, pose particularly challenging diagnostic and treatment obstacles. Early detection of these cancers is crucial…
- College: College
of
Medicine
(COM)
- Inventors: Croce, Carlo; Calin, George; Volinia, Stefano
- Licensing Officer: Willson, Christopher
Diagnostics and Prognostics of Prostate Cancer
TS-062299 — The Need: Addressing Prostate Cancer Diagnostics and Therapeutics
Prostate cancer remains a significant challenge in medical diagnosis and treatment, requiring advancements in diagnostics, therapeutics, and prognostics. Current approaches fall short in providing accurate and effective solutions, le…
- College: College
of
Medicine
(COM)
- Inventors: Croce, Carlo
- Licensing Officer: Willson, Christopher
MicroRNA signatures in human ovarian cancer
TS-062298 — The Need:
Ovarian cancer remains a significant challenge in the field of
medicine, with late-stage diagnosis and limited effective treatments contributing to high mortality rates. The need for improved diagnostic tools and targeted therapies is evident to address this aggressive disease. Convention…
- College: College
of
Medicine
(COM)
- Inventors: Croce, Carlo
- Licensing Officer: Willson, Christopher
Composition and Methods for Lung Cancer Diagnosis and Treatment
TS-062296 — The Need: Advancing Lung Cancer Detection and Treatment
Lung cancer continues to be a global health concern, accounting for the highest number of cancer-related deaths worldwide. In the United States, it is the leading cause of cancer mortality for both men and women, with a disheartening five-year…
- College: College
of
Medicine
(COM)
- Inventors: Croce, Carlo; Calin, George
- Licensing Officer: Willson, Christopher
Composition and Methods for Breast Cancer Diagnosis and Treatment
TS-062295 — The Need:
Breast cancer continues to be a significant health challenge, affecting a large number of women worldwide and remaining the second leading cause of cancer-related deaths among women in the United States. Despite advancements in detection and treatment, there is no universally successful m…
- College: College
of
Medicine
(COM)
- Inventors: Croce, Carlo; Calin, George
- Licensing Officer: Willson, Christopher
Diagnostic for Early Detection of Heart Damage
TS-059578 — A novel biomarker for the early identification
of cardiac damage, including chemotherapy-induced cardiotoxicity.
Despite significant medical advances and technologies, cardiovascular disease remains the number one cause of death in the United States, irrespective of gender or race, resulting in more than 600,000 annual deaths. Additionally, while cancer survivorship has increased significantly, the number one …
- College: College
of
Medicine
(COM)
- Inventors: Smith, Sakima; Dib, Patrick; McElroy, Craig
- Licensing Officer: Schultz, Teri
SARS-CoV-2 Diagnostic Assay with Sensors of Immune Activation
TS-050296 — A sequencing-based diagnostic assay for SARS-CoV-2 with sensors
of immune activation and the viral microbiota.
Diagnosis of SARS-CoV-2 infection, which is responsible for COVID-19 disease, is typically performed by molecular analysis of upper respiratory sampling (e.g. nasal swab). Transcriptional-mediated amplification (TMA) and quantitative (real-time) polymerase chain reaction (qPCR) using one or more v…
- College: College
of
Medicine
(COM)
- Inventors: Jones, Daniel; Avenarius, Matthew; Tu, Huolin
- Licensing Officer: Schworer, Adam
miRNA-based Predictive Model for Biochemical Failure Following Post-Prostatectomy Salvage Radiation Therapy
TS-037521 — A method to use MiRNA to predict the likelihood
of biochemical failure after radiation surgery.
The Need
Prostate cancer is one of the most common cancers worldwide, but current treatments can sometimes lead to complications. For example, radical prostatectomy is widely used for men in the early stages of prostate cancer, but long-term data shows that 30-40% of these patients experience bioch…
- College: College
of
Medicine
(COM)
- Inventors: Chakravarti, Arnab; Bell, Erica
- Licensing Officer: Schworer, Adam
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