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Containment System for Heating and Off-Gassing
TS-065424 — Due to environmental concerns and the decreasing supply of fossil fuels, there is substantial demand for nuclear-based energy production. Nuclear energy now provides about 10% of the world's electricity from about 440 power reactors and is the second largest source of low-carbon power. In addition, over 50 smaller countries utilize nuclear energy in about 220 research-size reactors. These reactors are used to produce medical and industrial isotopes and several other purposes.
It is essential to meet the safeguard requirements in liquid-fueled molten salt reactors, fuel salt transportation, and fuel cycle processes and to develop effective methods for measuring and monitoring the mass of molten fuel salt or coolant salt. However, due to the complex and dynamic nature o…
  • College: College of Engineering (COE)
  • Inventors: Van Zile, Matthew; Cao, Lei Raymond; Kauffman, Andrew
  • Licensing Officer: Zinn, Ryan

Skin Healing Technology: Dermal Substitutes and Engineered Skin with Rete Ridges
TS-064046 — Dermal substitute with engineered rete ridges improves epidermal-dermal communication and enhances burn wound treatment.
Massive burn injuries present a critical challenge in wound healing and prevention of infection. Current treatment methods are susceptible to blistering and other problems that can reduce engraftment. The Need Cultured epithelial autografts (CEAs) are a vital component in treating large burns, but…
  • College: College of Engineering (COE)
  • Inventors: Powell, Heather; Bailey, John; Blackstone, Britani "Niki"
  • Licensing Officer: Schultz, Teri

Adjustable Squatting Device for Constipation
TS-063959 — The Need Millions of individuals suffer from constipation due to the inability to relax pelvic floor muscles during bowel movements, leading to discomfort and strained efforts. Current solutions, like the Squatty Potty, lack adjustability and portability, limiting their effectiveness for a diverse …
  • College: College of Engineering (COE)
  • Inventors: Ruegsegger, Mark; Chakraborty, Subhankar; Gluzman, Isabella; Li, Yiqun; Piatkowski, Stephen; Puri, Raima
  • Licensing Officer: Bhatti, Hamid

Endoscopic additive manufacturing of biomaterials
TS-063919 — An articulating end effector for additive manufacturing that utilizes robot-assisted endoscopic surgery to implant synthetic tissues at local defects through “keyhole” incisions in patients. This innovative technology T2019-145 is part of a portfolio that also includes T2017-363. To learn more about both technologies, please visit https://oied.osu.edu/find-technologies and search using the phrase: Endoscopic additive manufacturing of biomaterials.
Robot-assisted surgery, tissue engineering, and additive manufacturing (AM) are emerging techniques in healthcare. Currently AM is used to develop synthetic tissues and organs, but open surgery is typically used to implant these scaffolds within the patient. This invasive procedure can subject pat…
  • College: College of Engineering (COE)
  • Inventors: Hoelzle, David; Asghari Adib, Ali; D'Souza, Desmond; Mansour, Daniel; Simeunovic, Andrej
  • Licensing Officer: Zinn, Ryan

High-K Dielectric barriers to suppress internal photoemission photocurrents
TS-063471 — In an increasingly digital world, the demand for efficient and reliable photodetectors is paramount. These devices are critical for a variety of applications, from medical imaging to defense systems. However, traditional photodetectors often struggle with low UV-visible rejection, limiting their e…
  • College: College of Engineering (COE)
  • Inventors: Rajan, Siddharth; McGlone, Joseph "Joe"; Wriedt, Nathan
  • Licensing Officer: Zinn, Ryan

A Regularized Conditional GAN for Posterior Sampling in Inverse Problems
TS-063238 — A novel regularization technique applicable for medical imaging applications that leverages conditional generative adversarial networks (cGANs) to generate reconstructed images in significantly shorter timeframes. The Need Several techniques are used for image reconstruction in the medical aren…
  • College: College of Engineering (COE)
  • Inventors: Bendel, Matthew; Ahmad, Rizwan; Schniter, Philip
  • Licensing Officer: Hampton, Andrew

Automated Endotracheal Intubation
TS-062900 — This cutting-edge technology redefines the intubation process by guiding the endotracheal tube into the airway with exceptional precision.
The Need Intubation is a critical medical procedure used to assist patients with breathing difficulties, executed through the insertion of an endotracheal tube (ET) into the windpipe. With over 313 million annual intubation procedures worldwide, ensuring first-pass success and minimizing complicati…
  • College: College of Engineering (COE)
  • Inventors: Ruegsegger, Mark; Elsayed-Awad, Hamdy; Hopping, Ethan; Lopez Vogler, Christian; Miles, Tim; Peiffer, Jordan
  • Licensing Officer: Bhatti, Hamid

Tracking Breast Tissue Tumor Cavity after Lumpectomy
TS-062715 — Radiopaque biodegradable polymer for the tracking of the breast tissue tumor cavity after lumpectomy and other radiation therapy applications
Approximately 40% of women diagnosed with breast cancer undergo a lumpectomy procedure. Approximately 170,000 lumpectomie are performed each yaer in the United States. Typically, this operation is followed by radiation therapy to ensure there are no remaining cancerous cells in the region. It is t…
  • College: College of Engineering (COE)
  • Inventors: Metzler, Sandra; Elisha, Deji; Evans, Izzy; Fedro, Joseph; Krakovsky, Mia; Sherry, Adam; Skoracki, Roman
  • Licensing Officer: Zinn, Ryan

Methods to measure biophysical attributes of the posterior eye
TS-062505 — The Need Glaucoma and myopia are significant causes of vision loss worldwide, affecting millions of people and imposing a substantial socioeconomical burden. Effective vision care strategies are urgently needed to reduce blindness caused by these conditions and mitigate their associated risks. In v…
  • College: College of Engineering (COE)
  • Inventors: Liu, Jun; Kwok, Sunny
  • Licensing Officer: Randhawa, Davinder

Methods for quantifying the biomechanical attributes of the cornea and the anterior sclera
TS-062497 — The Need: The field of ophthalmology requires advanced diagnostic tools to effectively diagnose, prevent, and treat various eye conditions. While ultrasound imaging is well-known in fields like pregnancy check-ups and vascular imaging, its potential in ophthalmology remains largely untapped. There …
  • College: College of Engineering (COE)
  • Inventors: Liu, Jun; Kwok, Sunny
  • Licensing Officer: Randhawa, Davinder

ANTENNA-IMPREGNATED FABRICS FOR RECUMBENT HEIGHT MEASUREMENT
TS-062493 — Children whose heights or growth rates fall outside of the normal range can be identified as having short stature (less than the 3rd percentile) or tall stature (above the 97th percentile) or as having abnormal growth velocity. Serial height measurements over time are key to identifying these patt…
  • College: College of Engineering (COE)
  • Inventors: Kiourti, Asimina; Militello, Lisa
  • Licensing Officer: Randhawa, Davinder

LRC-Circuit Based Smart Jewelry for Detection of Multiple Biomarkers in Sweat
TS-062489 — Biosensors are a powerful and emerging technology capable of measuring the presence and concentration of molecules inside the human body. These devices are based on the premise that the physiology of diseased tissue is substantially different from that of healthy tissue and can be used to diagnose a…
  • College: College of Engineering (COE)
  • Inventors: Li, Jinghua; Liu, Tzu Li
  • Licensing Officer: Ashouripashaki, Mandana

Automatic Implanted Port Access Device
TS-061547 — A venous access port device that leverages near-field communication (NFC) to automate needle placement as well as a disposable needle cartridge to increase the ease of and help maintain aseptic access to the port.
Venous access ports are central venous access devices that allow healthcare practitioners easy access to the patient’s veins to give treatment and take blood. Typically, these ports are made of non-irritant material and can remain under the skin for weeks or months. The Need Accessing a …
  • College: College of Engineering (COE)
  • Inventors: Garcia, Jodi; Johnson, Trey; Purdom, Kellie; Weiss, Solomon; Weiss, Simon; Yuhasz, Ben
  • Licensing Officer: Bhatti, Hamid

X-Ray Assistive Device for Standardizing the Knee Templating Process
TS-054471 — Knee templating is used as part of the pre-operative planning for knee replacement to determine the best fit for an implant. The current assistive devices used to determine fit are unreliable and inaccurate for proper patient fit. A new device is suggested to overcome these limitations.
Over 600,000 knee replacements are performed per year. As part of the pre-operative planning for surgery, x-ray images are taken to determine the proper fit for the implant. Even with the use of a calibration ball, this knee templating procedure remains inaccurate and unreliable for a number of re…
  • College: College of Engineering (COE)
  • Inventors: Ruegsegger, Mark; Aery, Dylan; Browske, Kimberly; Cantrell, Kaleb "Kaleb"; Reilman, Zach; Thew, Maddie
  • Licensing Officer: Randhawa, Davinder

Smart Platform for Engineered Electroceutical Dressings (SPEEDs) Enables Better Wound Care
TS-050245 — An integrated platform with multiple sensing modalities to actively orchestrate antimicrobial activity and wound healing.
Wound healing and disinfection for chronic wounds presents significant hurdles within the medical industry. Current state of art is inadequate and adds a significant cost burden to the healthcare system with many health and life-quality challenges for patients. After the formation of an open wound…
  • College: College of Engineering (COE)
  • Inventors: Prakash, Shaurya; Heald, Rachel; Mohana Sundaram, Prashanth; Narayanan, Kavya; Stoodley, Paul; Subramaniam, Vishwanath; Vilku, Gurleen; Wilgus, Traci; Wozniak, Daniel
  • Licensing Officer: He, Panqing

Integrally Joined Stainless Steel-NiTi Medical Devices
TS-050057 — A method for manufacturing surgical tools and implants with strong, gapless joints between NiTi (Nitinol) and stainless steel to capitalize on the best properties of both materials.
NiTi (Nitinol) is widely accepted and used for medical devices such as surgical tools and implants due to its biocompatibility and unique thermal-mechanical properties which provide super-elastic or shape memory responses. However, there are currently no commercial solutions for joining of NiTi to…
  • College: College of Engineering (COE)
  • Inventors: Panton, Boyd; Dapino, Marcelo; Gingerich, Mark; Headings, Leon; Morris, Jennifer
  • Licensing Officer: Zinn, Ryan

Integration of smart materials into surgical tools and medical devices using vaporizing foil actuator technology.
TS-045092 — Shape memory alloys are metals that "remember" their original shape when deformed and can return to their initial shape when heated. These shape memory alloys cannot currently be welded to other alloys, which significantly limits their use. Current state-of-the-art methods of joining sha…
  • College: College of Engineering (COE)
  • Inventors: Panton, Boyd; Daehn, Glenn; Vivek, Anupam
  • Licensing Officer: Zinn, Ryan

Biomimetic vitreous substitute with ocular drug delivery
TS-044490 — Methods and compositions for an antioxidant releasing hydrogel vitreous substitute
The vitreous humor is a fragile, transparent tissue between the lens and the retina of the eye that maintains the shape of the eye, acts as a shock absorber, and enables nutrient diffusion to ocular tissues. The vitreous also plays a key role in oxygen homeostasis. Over time, the vitreous degrades…
  • College: College of Engineering (COE)
  • Inventors: Reilly, Katelyn; Reilly, Matthew; Tram, Nguyen "Archie"
  • Licensing Officer: Schworer, Adam

DNA-cage erasable labels for fluorescence-based imaging
TS-043819 — Compositions and methods for analyzing multiple biomarkers without damaging tissue.
Histopathology is a cornerstone of tissue analysis used to diagnose many clinical conditions. Many of these diagnoses are based on identifying the presence of specific biomarkers, which can be indicated by colored labels. Currently, only 1-2 markers can be analyzed per slide, reducing accuracy and…
  • College: College of Engineering (COE)
  • Inventors: Winter, Jessica; Jergens, Elizabeth; Lee, Kil Ho "Kilho"
  • Licensing Officer: Willson, Christopher

Folding Transducer Array for Compact and Deployable Wave-Energy Guiding System
TS-043186 — A novel acoustic/ultrasonic wave-energy guiding system that utilizes structural topology to enhance directional and spectral sensitivities instead of phase delay, offering exceptional versatility and adaptable performance.
Although acoustic beamforming systems that are based on phase delays can be used to enhance directional and spectral sensitivities, each source or receiver must be individually controlled by appropriate phase delays to guide the acoustic energy radiation/reception sensitivities. This results in a …
  • College: College of Engineering (COE)
  • Inventors: Harne, Ryan
  • Licensing Officer: Zinn, Ryan

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