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Temperature-sensitive SARS-CoV-2 mutant TS11 for vaccine development
TS-059103 — Novel temperature-sensitive SARS-CoV-2 mutant
Current COVID-19 vaccines (mRNA, adenovirus vector, inactivated, S protein) are effective in preventing severe COVID-19 cases and deaths. However, they do not prevent infection/virus transmission and as the virus continues to evolve, S mutants may emerge that can escape current vaccine-induced immun…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Wang, Qiuhong; Liu, Mingde; Niu, Xiaoyu; Saif, Linda; Xu, Jiayu
  • Licensing Officer: Dahlman, Jason "Jay"

Novel Vaccine for Respiratory Syncytial Virus
TS-037299 — Recombinant vesicular stomatitis virus (rVSV) vaccines to fight against respiratory syncytial virus (RSV) infections.
Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory tract illness (ALRI) in infants, children, and the elderly, and often leads to fatal bronchiolitis and pneumonia. About 3.4 million children under the age of five are hospitalized each year due to an acute RSV in…
  • College: College of Veterinary Medicine
  • Inventors: Niewiesk, Stefan; Binjawadagi, Basavaraj; Li, Jianrong; Peeples, Mark
  • Licensing Officer: Dahlman, Jason "Jay"

Unmanned Aerial System Stinger-Suspended Crop Health Sensing
TS-036526 — A remote sensing imaging system that combines a suspended camera with sampling probes, combined with unique image processing features.
Unmanned Aerial Systems (UAS) allow agricultural producers to generate high-resolution crop health data over large areas. UAS generate this data by imaging the upper canopy while flying above row crops. However, most crop health problems originate below the upper portion of the canopy. Most causes…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Shearer, Scott; Klopfenstein, Andrew "Andrew"; See, David; Weigman, Christopher
  • Licensing Officer: Dahlman, Jason "Jay"

Methods to Improve Mucosal Immune Response During Vaccination
TS-015239 — A method for enhancing the mucosal (IgA) immune response by transiently blocking a specific cellular subset during vaccination.
Mucosal IgA are immunoglobulins (antibodies) that play a key role in the defense of mucosal tissues by neutralizing pathogenic microorganisms and toxins and interfering with bacterial or viral colonization of the epithelium. An important component of needle-free vaccines is induction of mucosal Ig…
  • College: College of Veterinary Medicine
  • Inventors: Boyaka, Prosper
  • Licensing Officer: Dahlman, Jason "Jay"

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