Cell-Penetrating Peptides: Revolutionizing Intracellular Delivery
TS-066751 —
In the rapidly evolving field of biotechnology and pharmaceuticals, there is a critical need for efficient delivery mechanisms to transport therapeutic agents directly into cells. Traditional methods face challenges with membrane impermeability and degradation of therapeutic compounds, limiting th…
- College: College of Arts & Sciences
- Inventors: Pei, Dehua
- Licensing Officer: Dahlman, Jason
"Jay"
IDEAS: Revolutionizing Early Childhood Education with Automated Interaction Analysis
TS-065825 — The Need: In early childhood education settings, understanding children's interactions, both social and linguistic, is paramount for effective teaching and development monitoring. However, manual observation and analysis of these interactions can be time-consuming and subjective, hindering educa…
- College: College of Education & Human Ecology
- Inventors: Gonzalez Villasanti, Hugo "Hugo"; Justice, Laura
- Licensing Officer: Dahlman, Jason
"Jay"
Scalable Nanoparticle Synthesis for Precision Applications
TS-064181 —
In the rapidly evolving landscape of nanotechnology, there exists a critical demand for scalable and efficient methods of producing nanoparticles. Current approaches, often confined to small-scale batches, hinder the widespread implementation of nanomaterials in diverse fields such as medicine, bi…
- College: College of Engineering (COE)
- Inventors: Winter, Jessica; Ruan, Gang
- Licensing Officer: Dahlman, Jason
"Jay"
Unveiling Biochemically Responsive MR Probes for Precision Beyond Limits
TS-064179 —
In the realm of medical diagnostics, the need for precise and non-invasive detection of molecular-level pathology has been a longstanding challenge. Traditional imaging techniques often fall short in providing detailed insights into biological processes at this scale. To address this gap, there is…
- College: College of Arts & Sciences
- Inventors: Shafaat, Hannah "Hannah"
- Licensing Officer: Dahlman, Jason
"Jay"
Network-based Approach for Accurate Brain Modeling
TS-062628 — More than a billion people worldwide suffer from some neurological disorders, such as Alzheimer's, Parkinson's, multiple sclerosis, epilepsy, stroke, autism, addiction, and many others. These conditions result in more than 7 million deaths, with associated costs exceeding $1.5 trillion annua…
- College: College of Arts & Sciences
- Inventors: Cranmer, Skyler; Bhamidi, Shankar; Denny, Mathew; Desmarais, Bruce; Lu, Zhong-Lin; Stillman, Paul; Wilson, James
- Licensing Officer: Dahlman, Jason
"Jay"
Advanced AAV Gene Therapy Characterization Technique
TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …
- College: College of Arts & Sciences
- Inventors: Wysocki, Vicki; Cleary, Sean; Du, Chen
- Licensing Officer: Dahlman, Jason
"Jay"
Tunable Fingerloop DNA antisense motifs for nucleic acid targeting and detection technologies
TS-062555 — The Need: Improved Nucleic Acid Detection Probes
There is a growing need for advanced detection probes that can effectively identify target nucleic acid sequences while reducing binding to mismatched targets. Existing technologies often suffer from false positive results due to temperature fluctuat…
- College: College of Arts & Sciences
- Inventors: Lease, Richard
- Licensing Officer: Dahlman, Jason
"Jay"
Functional "fingerloop" DNA antisense motifs for nucleic acid targeting and detection technologies
TS-062547 — The Need: The field of molecular biology and genetic engineering faces challenges in achieving precise and accurate detection and amplification of target nucleic acid sequences. Traditional hybridization technologies suffer from the issue of mismatched targets, leading to reduced specificity and rel…
- College: College of Arts & Sciences
- Inventors: Lease, Richard
- Licensing Officer: Dahlman, Jason
"Jay"
Novel use of novobiocin to potentiate the antimicrobial efficacy of polymyxins
TS-062439 — The Need: Addressing the Growing Threat of Gram-Negative Bacterial Infections
Gram-negative bacterial pathogens, including Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae, are responsible for more than 35% of common hospital-acquired infections. These no…
- College: College of Arts & Sciences
- Inventors: Kahne, Daniel; Baidin, Vadim; Mandler, Michael; Ruiz, Natividad
- Licensing Officer: Dahlman, Jason
"Jay"
Medical Food for Cystic Fibrosis
TS-062420 — The Need: Addressing Nutritional Challenges in Cystic Fibrosis
Cystic Fibrosis (CF) presents significant nutritional challenges for individuals living with the condition. Due to the increased energy requirements and difficulties in nutrient absorption, CF patients often struggle to maintain adequat…
- College: College of Education & Human Ecology
- Inventors: DiSilvestro, Robert
- Licensing Officer: Dahlman, Jason
"Jay"
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