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Rabbit Model for Duchenne Muscular Dystrophy
TS-058084 — A rabbit model has been created for Duchenne Muscular Dystrophy (DMD) that more closely resembles the effects experienced in humans while being more cost effective compared to larger animal models.
There has yet to be a DMD animal model that bridges the gap between cost effectiveness and scientific relevance. This new rabbit model does that. DMD is a lethal genetic disease characterized by progressive muscle weakness and muscle wasting. There are several animal models for DMD, includin…
  • College: College of Medicine (COM)
  • Inventors: Han, Renzhi
  • Licensing Officer: Davis, Stewart

A novel mouse model of spontaneous chronic lymphocytic leukemia
TS-055268 — The laboratory of Dr. Rosa Lapalombella in collaboration with Dr. James Blachly at The Ohio State University has developed a mouse model of spontaneous Chronic Lymphocytic Leukemia.
The Need Chronic lymphocytic leukemia (CLL) accounts for one quarter of new cases of leukemia. CLL is the most prevalent adult leukemia in Western countries and is characterized by a mature B-cell phenotype. Given the burden of this disease, a large pipeline of drugs for treatment are in progress…
  • College: College of Medicine (COM)
  • Inventors: Lapalombella, Rosa; Blachly, James; Byrd, John
  • Licensing Officer: Davis, Stewart

Method for controlling multiple heterogenous magnetic bacteria at a solid-liquid interface using uniform magnetic fields
TS-053222 — Manipulatable miniaturized robots have a variety of applications in biomedical sciences, specifically microrobots capable of navigating in vivo blood vessels have the potential to revolutionize non-invasive surgery and targeted drug delivery for cancer and other disease treatment. Drug discovery c…
  • College: College of Arts & Sciences
  • Inventors: Wijesinghe, Hiran
  • Licensing Officer: Hong, Dongsung

Novel Large Scale All-Male Bluegill Production Technology & All-Female Yellow Perch Production Technology
TS-043636 — A novel technique for the large scale production of male bluegill (GMB) stock through selective breeding methods and for large scale production of all female yellow perch fish stock by means of dietary supplements. This technique improves growth rate, size, and survivability. For more information, please see related pdf upload.
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Wang, Hanping
  • Licensing Officer: Dahlman, Jason "Jay"

Quadruplex-based non-enzymatic DNA signal amplification
TS-042905 — A quadruplex-based non-enzymatic DNA signal amplification scheme for point of care diagnostic testing.
Currently, non-enzymatic signal amplification assays, an alternative to PCR, are complicated reactions employing multiple DNA constructs. The most successful non-enzymatic assays rely on stand-displacement reactions within DNA duplexes that result in background activity. Because of this background…
  • College: College of Arts & Sciences
  • Inventors: Kankia, Besik
  • Licensing Officer: Willson, Christopher

Paper-based Dried Blood Spheroids for Stabilization of Labile Organic Compounds Stored in Ambient Air
TS-038604 — Apparatus and methods to form three-dimensional dried blood spheroids on hydrophobic paper substrates.
Dried blood spots on paper substrates offer a facile sample collection, storage, and transportation approach for biofluids. However, variable diffusion, volcanic effects, analyte instability, and difficulty in recovering samples from paper plague this method, lowering confidence in analyte quantif…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Damon, Deidre
  • Licensing Officer: Ashouripashaki, Mandana

Novel small peptide polarizing agents for dynamic nuclear polarization (DNP) nuclear magnetic resonance (NMR) spectroscopy
TS-038322 — Versatile small biradical peptide molecules that can serve as biradical polarizing agents for dynamic nuclear polarization (DNP) solid-state nuclear magnetic resonance spectroscopy.
DNP methodology offers dramatic sensitivity enhancements of NMR experiments (up to 1-2 orders of magnitude) by transferring the large electron spin polarization to the nuclei of interest, and is currently one of the research frontiers in the magnetic resonance field with numerous applications to b…
  • College: College of Arts & Sciences
  • Inventors: Jaroniec, Christopher; Conroy, Daniel
  • Licensing Officer: Willson, Christopher

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