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Instant Diagnostics, Anywhere
TS-070543 — A Platform for High-Throughput Biomarker Detection that is portable, fast, and requires minimal sample
The Need The diagnostics market is under increasing pressure to deliver faster, more reliable, and less invasive solutions, driven by growing global health challenges. Current technologies face critical limitations, including large sample requirements, labor-intensive workflows, and reliance on exp…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Seth, Ayesha; Zerrudo, Stephanee
  • Licensing Officer: Panic, Ana

NanoPlex: Rapid, Memory-Efficient Nanopore Data Solutions for Modern Labs
TS-070331 — Accelerate discovery and streamline workflows with a next-generation platform for high-throughput nanopore data extraction.
Overview Nanopore sensing is revolutionizing genomics, proteomics, and diagnostics, but the explosive growth in data volume has outpaced the capabilities of current analysis tools. Researchers often face bottlenecks due to slow processing speeds, memory limitations, and the need for specialized …
  • College: College of Arts & Sciences
  • Inventors: Bandara, Nuwan
  • Licensing Officer: Panic, Ana

Aerobiology Chamber for Pilot-scale Studies
TS-070103 — The Need Aerobiology chambers on the market today face several challenges, particularly in studying biohazardous aerosols and testing anti-bioaerosol agents. Large, room-sized chambers, while capable of mimicking indoor environments, are cumbersome to operate, require extensive decontamination, an…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Yousef, Ahmed; Ali, Mohamed; Kasler, David; Kwiek, Jesse; Sastry, Sudhir
  • Licensing Officer: Panic, Ana

Direct Analysis of Air and Water Sensitive Material by In-Chamber Ionization Mass Spectrometry
TS-067160 — The Need Due to the unparalleled ability of Mass spectrometry (MS) to identify and quantify substances at the molecular level it is an indispensable tool in various industries, from pharmaceuticals and forensics to environmental monitoring and materials science. However, the power of MS is often hi…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Hadad, Christopher; Lalisse, Remy; Sahraeian, Taghi; Wu, Yiying; Zheng, Jingfeng
  • Licensing Officer: Panic, Ana

Co-Axial Contained Electrospray Ionization Platform for Mass Spectrometry
TS-067158 — The Need Mass spectrometry (MS) is used across a wide range of applications for detection of various chemical analytes such as drug metabolites, pesticides, food adulterants, and natural product extracts. Recent developments have transformed MS into an all-purpose technique for in-situ and real-tim…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Burris, Benjamin "Ben"; Grooms, Alex; Heiss, Derik; Kulyk, Dmytro
  • Licensing Officer: Panic, Ana

Biofilm Detachment Monitoring for Enhanced Oral Health Solutions
TS-066772 — The Need Biofilms, particularly dental plaque-biofilms, are communities of microorganisms encased in a slimy extracellular polymeric substance (EPS) that adhere to surfaces or neighboring microorganisms. These biofilms are responsible for various infectious diseases, including oral diseases such as…
  • College: College of Medicine (COM)
  • Inventors: Stoodley, Paul "DECEASED"; Gloag, Erin
  • Licensing Officer: Willson, Christopher

Dynamic Spray Mass Spectrometry: A Versatile Solution for Comprehensive Molecular Analysis
TS-066752 — Background: Mass spectrometry is an analytical technique characterized by its excellent sensitivity, robust selectivity, and rapid response. The four stages of mass spectrometry are ionization, acceleration, separation, and detection. Among these, the ionization step is crucial for analyzing comple…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Damale, Purva; Grooms, Alex; Kulyk, Dmytro
  • Licensing Officer: Panic, Ana

3D Object-based Segmentation-based Quantification of Spatial Protein Organization (OBS3D)
TS-066233 — Protein analysis is foundational to understanding human physiology and is helpful for basic research, diagnosis, guiding treatment, and monitoring of human disease. There are several widely used platforms for evaluating protein function. The primary tools used in protein analysis on cells and tissues include antibody/aptamer, fluorescent detection systems, and mass spectrometry.
Colocalization analysis is the current standard technique for assessing spatial association of co‐labeled proteins in cells using multicolor immunofluorescence images. However, these tools are limited because multiple antigens nearby exhibit overlapping staining, which leads to inaccurate analys…
  • College: College of Engineering (COE)
  • Inventors: Veeraraghavan, Rengasayee
  • Licensing Officer: Zinn, Ryan

System for automated high-speed imaging and genetic manipulation of C. elegans on agar media
TS-065892 — The Need The microscopic worm C. elegans is a model animal studied in more than 1500 biological and medical research laboratories worldwide due to its genetic manipulability and optical transparency. In C. elegans research, the manual process of picking worms between plates presents a significant …
  • College: College of Engineering (COE)
  • Inventors: Fang-Yen, Christopher "Chris"; Alhalbi, Serge; Li, Zihao
  • Licensing Officer: Randhawa, Davinder

Specific Pathogen Free Turkey Eggs
TS-065846 — The Need: With the persistent threat of avian diseases, ensuring the health and safety of turkey populations is of utmost importance to the poultry industry. Traditional methods of disease prevention have limitations, necessitating a technology that can reliably produce Specific Pathogen Free (SPF) …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Saif, Mo
  • Licensing Officer: Panic, Ana

Protease-free Bacillus subtilis host
TS-065845 — The Need: In the realm of biotechnology, the challenge of synthesizing enzymes, pharmaceuticals, and fine chemicals efficiently is paramount. However, the presence of multiple proteases secreted by Bacillus subtilis 168 during growth stages poses a significant obstacle to achieving optimal productio…
  • College: College of Arts & Sciences
  • Inventors: Zeigler, Daniel
  • Licensing Officer: Willson, Christopher

SUMO^RIT Tag: Revolutionizing Downstream Gene Translation
TS-065844 — The Need: In modern biotechnology and pharmaceutical industries, precise control over gene expression is paramount. However, conventional translation processes often lead to inefficiencies, resulting in reduced yields and compromised protein function. Meeting the demand for enhanced gene expression …
  • College: College of Arts & Sciences
  • Inventors: Law, Jamison
  • Licensing Officer: Panic, Ana

3D printed hemlock twig key tag showing feeding locations of hemlock woolly adelgid (HWA) and elongate hemlock scale (EHS)
TS-065837 — The Need: In the fight against invasive species threatening our forests, rapid and accurate identification is paramount. Traditional methods for monitoring pests like the Hemlock Woolly Adelgid (HWA) and Elongate Hemlock Scale (EHS) can be time-consuming and imprecise, leading to delayed responses a…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Basnagala, Suranga; Perry, Kayla
  • Licensing Officer: Panic, Ana

3D printed Elm leaves to show Elm Zigzag Sawfly (Aproceros leucopoda) larval feeding damage.
TS-065836 — The Need: In today's agricultural landscape, precise identification and monitoring of pest damage are paramount for maintaining crop health and maximizing yields. Traditional methods often fall short in accurately assessing and addressing the impact of pests like the Elm Zigzag Sawfly (Aproceros…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Basnagala, Suranga; Perry, Kayla
  • Licensing Officer: Panic, Ana

Precision RNA-PROTACs: Revolutionizing Therapeutic Targeting of Dysregulated Ribonucleoprotein Complexes
TS-065457 — The Need: In the realm of therapeutic development, there's a pressing need for precise targeting of dysregulated ribonucleoprotein (RNP) complexes to combat various diseases, particularly neurodegenerative disorders like ALS, Alzheimer’s, and Huntington’s diseases. Traditional metho…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"; Strong, Rebekah
  • Licensing Officer: Panic, Ana

Revolutionizing RNA-Protein Interaction Mapping: Precision Proximity Labeling Technology
TS-065456 — The Need In modern biological research, there is a pressing demand for technologies that enable precise mapping of RNA-protein interactions within Ribonucleoprotein (RNP) complexes. Traditional methods often lack the capability to pinpoint these interactions at the level of secondary structure moti…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"
  • Licensing Officer: Panic, Ana

Advancing RNA Detection with Innovative Peptide-Based Fluorescent Probes
TS-065455 — The Need: In modern biotechnology and biomedical research, there is an escalating demand for efficient tools that can accurately detect and analyze specific RNA sequences. The ability to precisely target and identify RNA molecules, particularly U-rich sequences, is crucial for various applications s…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; DeSantis, Christopher; Gopalan, Venkat; Liang, Yufeng; Mao, Jie; Marathe, Ila; Miao, Shiqin "Shiqin"
  • Licensing Officer: Panic, Ana

Revolutionizing Pharmaceutical Synthesis: Advancements in Metal-Catalyzed Coupling Technology
TS-064824 — The Need In the pharmaceutical industry, the synthesis of complex organic substrates is crucial for the development of life-saving medications. However, traditional metal-catalyzed coupling reactions often face significant challenges when applied to these complex substrates, leading to high failure…
  • College: College of Arts & Sciences
  • Inventors: Sevov, Christo; Dinh, Long; Hamby, Taylor; Starbuck, Hunter
  • Licensing Officer: Panic, Ana

Magnetic Nanoparticles for Cancer Cell Classification
TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year. The Need Developing drugs for cance…
  • College: College of Arts & Sciences
  • Inventors: Schultz, Zachary; Rist, David; Skardal, Aleksander; Venere, Monica
  • Licensing Officer: Panic, Ana

Drosophila melanogaster muscle stem cell line
TS-064271 — The Need In the rapidly advancing landscape of life sciences, researchers and biotech companies face an escalating demand for reliable and versatile cell lines. The need for a specialized cell line that combines adaptability, reproducibility, and ease of use is paramount in accelerating breakthroug…
  • College: College of Arts & Sciences
  • Inventors: Simcox, Amanda
  • Licensing Officer: Dahlman, Jason "Jay"

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