TS-048975 — A mechanical ventilation device which incorporates a hand-crank to enable automated breathing assistance without the need for electrical outlets or external generators.

TS-048888 — Liposome drug delivery systems play a significant role in the formulation of new therapies. These liposome-encapsulated drugs are used to treat a wide range of diseases such as cancer, influenza, and hepatitis. While endogenous liposomes are recognized by the mononuclear phagocyte system and clear…

TS-048738 — Novel electrochemical recycling method for selective and scalable reduction of triphenylphosphine oxide to triphenylphosphine

TS-048726 — Novel, transition metal-free catalysts capable of alkyne hydrogenation and semihydrogenation under modest conditions.

TS-048646 — A novel method to detect a counterfeit integrated circuit (IC) and to authenticate an IC using the electromagnetic characteristics of the IC and a resonator

TS-048645 — A novel photon-assisted MOCVD growth method to synthesize II-IV-N2 materials

TS-048644 — The potential of different materials for vertical power switching is often assessed by calculating the Baliga Figure of Merit (BFOM). In the case of wide and ultra-wide bandgap materials, the high breakdown fields and the relatively good transport properties make the BFOM significantly higher than…

TS-048641 — A method of authenticating an IC die’s origin and uniquely identifying each die with an intrinsic unclonable value through measurement of on-chip capacitance values

TS-048635 — A novel edge termination concept using extreme permittivity dielectrics is proposed to effectively manage peak electric fields in vertical power devices

TS-048632 — A method for mitigating the BLE vulnerability in an IoT device that protects UUIDs from being harvested and reverse engineered

TS-048591 — An embedded coax proximity sensor for the detection of hands or other objects near a vehicle's steering wheel

TS-048588 — A lightweight power module that reduces loop stray inductance while maintaining good electrical insulation and thermal dissipation.

TS-048123 — A method for automatically calibrating and optimizing gear shift control parameters through iterative algorithms both during development and during use.

TS-048065 — A new magnesium alloy designed using computational thermodynamic and kinetic models, which possesses optimal mechanical and formability performance suitable for industrial applications

TS-047830 — An automated technique and system which combines electrospinning, additive manufacturing, and cell dispensing for generating high-quality tissue constructs with high physiological relevance.

TS-047335 — New IR detector combining a dielectric resonator antenna (DRA) with a semiconductor absorber for improved signal, noise, and speed performance

TS-047296 — A neural network that utilizes a simple and efficient single antenna optimization framework

TS-047136 — A range of low-cost gas sensors for non-invasive diagnostic tests and health monitoring.

TS-047118 — Analogues of verticillin which have more useful drug-like properties than the verticillin parent compounds alone, including increased solubility, absorption, and stability, all while maintaining similar anticancer potency to the original compounds.

TS-046978 — Transcription factors that can upregulate desired genes in diseased tissue to reprogram diseased cells, thereby reversing the disease and creating healthy non-diseased phenotype genes. These transcription factors would be especially useful in musculoskeletal diseases such as back pain and osteoarthritis.

TS-046905 — Porcine epidemic diarrhea virus (PEDV) has historically been an exotic disease to the U.S.. As of May, 2013, the virus made its way from China to the U.S.. This virus causes nearly 100% mortality in piglets and ranges from 80-90% morbidity. There is currently no PEDV vaccine in production. This inve…

TS-046794 — Methods of purifying proteins that can be used in various applications such as drug delivery and detoxification of byproducts of hemolysis.

TS-046751 — A novel sensor for the screening of field crops, one example being the amino acids in soybeans. This allows the quality and nutritional value of the soybeans to be evaluated quickly and simply. This technology would benefit not only farmers and producers of soybeans and soy products, but also consumers by manufactures to know the quality of the ingredients received to be monitored.

TS-046581 — Novel halide perovskite phosphor that, when paired with blue LED light, creates warm white light without the need for high temperature ceramics in its production and does not contain rare-earth elements. It has several applications including solid-state lighting and white LEDs. The phosphors produce light with a natural appearance and extended excitation spectra.

TS-046454 — Original, synthetic complexes used to detoxify hemoglobin, heme, and free iron in patients suffering from hemolysis. The use of these complexes would allow effective treatment of various states of hemolysis and would mitigate the numerous side effects associated with the condition. Complexes could also be used as a drug carrier for targeting CD163+ macrophages and monocytes.

TS-046029 — Next-generation agricultural sensor technology enables precise, data-based decision-making to be implemented at the farm level. Field operations data such as granular fertilizer application rates are useful to the producer, because optimization of nutrient supplementation increases use efficiency …

TS-045881 — The Need Cell therapies have received recent approvals for immunomodulatory indications. Immuno-activating chimeric antigen receptor (CAR)–T cells have been developed for cancers, whereas immunosuppressive mesenchymal stromal cells (MSCs) have been approved for inflammatory bowel disease and …

TS-045681 — Cas9-derived constructs can be used to modulate gene expression, but physical limitations restrict the application of this technique. Researchers at The Ohio State University have overcome this obstacle by engineering new Cas9-derived transcription factors.

TS-045637 — Modification to PI3K/mTOR inhibitor, PI-103, for conjugation to RNA nanoparticles for targeted drug delivery to cancer cells via folate receptor targeting.

TS-045448 — Maximized mRNA lifespan and translation for mRNA-based therapy applications.