TS-050057 — A method for manufacturing surgical tools and implants with strong, gapless joints between NiTi (Nitinol) and stainless steel to capitalize on the best properties of both materials.

TS-050056 — This testbed serves as a virtual way to increase security assurance in the automotive design phase. With connectivity becoming such a prominent aspect of automotive design security risks can also risk safety. The goal is to be able to provide a stronger assurance of security in modern vehicles.

TS-050050 — A method for filtering malicious messages on a CAN Network. This method is a physics, model, based method that utilizes knowledge of the CAN network as well as the physics of the systems being controlled to remove malicious messages from effecting the intended function of the controls algorithms on vehicles.

TS-050046 — Methods using miRNAs for early Alzheimer’s Disease diagnoses and altered expression of key autophagy related proteins

TS-049909 — A control method based upon properties of linear systems to manipulate the vibrational amplitudes and frequencies of structural systems by exploiting piecewise-linear (PWL) nonlinearities.

TS-049903 — A scalable, adaptive computational platform (software) that performs accurate, predictive computer simulations in less time, with the end goal of supporting a decision-making agency

TS-049730 — Dysregulated fat metabolism is an established hallmark of cancer cells. However, the disruption of lipid homeostasis in cancer cells remains an elusive target for therapy. Diacylglycerol-acyltransferase (DGAT) regulates the final and committed step for triglyceride synthesis. There are two known i…

TS-049505 — An engineered base editor (iABE-NG) that uses an SpCas9 variant, a shortened adenine deaminase domain with eliminated RNA off-targeting activity, and an intein split for packaging into an adeno-associated virus (AAV), resulting in gene mutation correction.

TS-049471 — Listeriosis is an infectious disease caused by the bacterial pathogen Listeria monocytogenes. Although the average number of cases is moderate in the United States (1600-2500/year), listeriosis is a significant health concern due to its exceptionally high fatality rate. Indeed, listeriosis is the …

TS-048975 — A mechanical ventilation device which incorporates a hand-crank to enable automated breathing assistance without the need for electrical outlets or external generators.

TS-048888 — Liposome drug delivery systems play a significant role in the formulation of new therapies. These liposome-encapsulated drugs are used to treat a wide range of diseases such as cancer, influenza, and hepatitis. While endogenous liposomes are recognized by the mononuclear phagocyte system and clear…

TS-048738 — Novel electrochemical recycling method for selective and scalable reduction of triphenylphosphine oxide to triphenylphosphine

TS-048726 — Novel, transition metal-free catalysts capable of alkyne hydrogenation and semihydrogenation under modest conditions.

TS-048646 — A novel method to detect a counterfeit integrated circuit (IC) and to authenticate an IC using the electromagnetic characteristics of the IC and a resonator

TS-048645 — A novel photon-assisted MOCVD growth method to synthesize II-IV-N2 materials

TS-048644 — The potential of different materials for vertical power switching is often assessed by calculating the Baliga Figure of Merit (BFOM). In the case of wide and ultra-wide bandgap materials, the high breakdown fields and the relatively good transport properties make the BFOM significantly higher than…

TS-048641 — A method of authenticating an IC die’s origin and uniquely identifying each die with an intrinsic unclonable value through measurement of on-chip capacitance values

TS-048635 — A novel edge termination concept using extreme permittivity dielectrics is proposed to effectively manage peak electric fields in vertical power devices

TS-048632 — A method for mitigating the BLE vulnerability in an IoT device that protects UUIDs from being harvested and reverse engineered

TS-048591 — An embedded coax proximity sensor for the detection of hands or other objects near a vehicle's steering wheel

TS-048588 — A lightweight power module that reduces loop stray inductance while maintaining good electrical insulation and thermal dissipation.

TS-048123 — A method for automatically calibrating and optimizing gear shift control parameters through iterative algorithms both during development and during use.

TS-048065 — A new magnesium alloy designed using computational thermodynamic and kinetic models, which possesses optimal mechanical and formability performance suitable for industrial applications

TS-047830 — An automated technique and system which combines electrospinning, additive manufacturing, and cell dispensing for generating high-quality tissue constructs with high physiological relevance.

TS-047335 — New IR detector combining a dielectric resonator antenna (DRA) with a semiconductor absorber for improved signal, noise, and speed performance

TS-047136 — A range of low-cost gas sensors for non-invasive diagnostic tests and health monitoring.

TS-047118 — Analogues of verticillin which have more useful drug-like properties than the verticillin parent compounds alone, including increased solubility, absorption, and stability, all while maintaining similar anticancer potency to the original compounds.

TS-046978 — Transcription factors that can upregulate desired genes in diseased tissue to reprogram diseased cells, thereby reversing the disease and creating healthy non-diseased phenotype genes. These transcription factors would be especially useful in musculoskeletal diseases such as back pain and osteoarthritis.

TS-046905 — Porcine epidemic diarrhea virus (PEDV) has historically been an exotic disease to the U.S.. As of May, 2013, the virus made its way from China to the U.S.. This virus causes nearly 100% mortality in piglets and ranges from 80-90% morbidity. There is currently no PEDV vaccine in production. This inve…

TS-046794 — Methods of purifying proteins that can be used in various applications such as drug delivery and detoxification of byproducts of hemolysis.