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Modular Generative AI Framework for Efficient Molecular Discovery
TS-074599 — Discovering molecules that simultaneously satisfy multiple competing design criteria is a resource-intensive challenge across the pharmaceutical, energy, and materials industries. The enormity of chemical space makes exhaustive screening impractical, while existing AI-guided methods either restric…
  • College: College of Engineering (COE)
  • Inventors: Paulson, Joel; Muthyala, Madhav Reddy; Sorourifar, Farshud; Tan, Tianhong
  • Licensing Officer: Randhawa, Davinder

Human–AI Interaction Research Platform
TS-074578 — Opportunity Overview This technology is a web‑based, multi‑user platform designed to rigorously study how people interact with AI systems in real time. Unlike traditional survey tools or product A/B testing environments, the platform supports live human–AI collaboration while capturing …
  • College: College of Arts & Sciences
  • Inventors: Meng, Jingbo
  • Licensing Officer: Panic, Ana

Data‑Driven Powertrain Recommender Systems (PRS) for Optimized Truck Fleets
TS-073692 — Fleet operators face increasing pressure to reduce operating costs and emissions while maintaining performance and reliability. Choosing the “right” truck (diesel, alternative fuel, or battery electric) for a specific duty cycle remains largely heuristic, conservative, and error‑prone. As a …
  • College: College of Engineering (COE)
  • Inventors: Ahmed, Qadeer; Subraya-Hegde, Sharat; Villani, Manfredi
  • Licensing Officer: Ashouripashaki, Mandana

Free Energy Spectroscopy: Transforming Molecular Analytics for Next-Generation Biotech and Pharma
TS-071946 — Powering faster, smarter decisions with real-time molecular insights for research and therapeutic development.
Overview Pharmaceutical and biotech companies often face delays and uncertainty in new drug development due to insufficient experimental insight into the shifting behaviors of large biomolecular complexes— processes critical to understanding disease and drug mechanisms. Free Energy Spectrosco…
  • College: College of Arts & Sciences
  • Inventors: Poirier, Michael; Bonin, Kalven; Bundschuh, Ralf; Castro, Carlos
  • Licensing Officer: Panic, Ana

Forecast Amplifier-Triple Your Weather Ensemble Quickly and Affordably
TS-071915 — An ultra‑efficient probit‑space ensemble expansion approach triples the size of weather‑forecast ensembles by producing hundreds of realistic “virtual” members from existing runs using minimal compute time and expert statistical knowledge.
Modern weather models are extremely complex, and each forecast can only be simulated a limited number of times. This means forecasters often have just 50–100 versions of a prediction to work with, even though the atmosphere itself is vastly more complicated. With so few samples, important de…
  • College: College of Arts & Sciences
  • Inventors: Chan, Man-Yau "Joseph"
  • Licensing Officer: Panic, Ana

AI-Driven Intersection Safety System for Vulnerable Road User Protection
TS-070954 — The Need Intersections are among the most dangerous areas on U.S. roadways, accounting for approximately 25% of traffic fatalities and nearly half of all injuries annually. Vulnerable Road Users (VRUs), including pedestrians and cyclists, face increasing risk due to complex traffic dynamics and limi…
  • College: College of Engineering (COE)
  • Inventors: Yurtsever, Ekim; Giuliani, Michele; Rizzoni, Giorgio
  • Licensing Officer: Ashouripashaki, Mandana

HyperXtract: Rapid, Memory-Efficient Data Extraction for Nanopore Data
TS-070331 — Accelerate discovery and streamline workflows with a next-generation platform for high-throughput nanopore data extraction.
The Need Nanopore sensing is revolutionizing genomics, proteomics, and diagnostics, but the explosive growth in data volume has outpaced the capabilities of current analysis tools. Researchers often face bottlenecks due to slow processing speeds, memory limitations, and the need for specialized har…
  • College: College of Arts & Sciences
  • Inventors: Bandara, Nuwan
  • Licensing Officer: Panic, Ana

SyMANTIC – Novel Symbolic Regression to Discover Accurate Models from Data
TS-069523 — The Need In many scientific and industrial fields, there is a critical need for interpretable and accurate models that can be derived from complex datasets. Traditional machine learning methods often produce black-box models that lack transparency and interpretability, making it difficult to unders…
  • College: College of Engineering (COE)
  • Inventors: Muthyala, Madhav Reddy; Paulson, Joel; Sorourifar, Farshud
  • Licensing Officer: Randhawa, Davinder

Optimal and Pure Leaf Classification Trees for Machine Learning (ML) Decision-Making
TS-067550 — A method to improve the performance and accuracy of ML-based decision trees.
Decision trees are popular machine learning (ML) methods used in classification and regression problems, and they have numerous applications in the real world. Various industries use decision trees to help decide strategies, investments, and operations. In addition, they are used in healthcare to he…
  • College: College of Engineering (COE)
  • Inventors: Allen, Theodore "Ted"; Arrey, Evelyn; Booth, Matthew; Liu, Enhao; Mashayekhi, Medhi
  • Licensing Officer: Giles, David

Unlocking Hidden Opportunities: The Power of Multi-Solution Spatial Aggregation
TS-067434 — The Need Spatial aggregation is crucial in numerous industries where data from low-level spatial units, such as census blocks, must be grouped into larger, meaningful regions. Traditional approaches often struggle with the computational complexity of these tasks and tend to focus on finding a singl…
  • College: College of Arts & Sciences
  • Inventors: Xiao, Ningchuan
  • Licensing Officer: Dahlman, Jason "Jay"

BDAMPER: Advanced Application Software for Dynamic Analysis and Design of Friction Damper Structures
TS-066234 — In the realm of rotating machinery and structural engineering, the need to manage and mitigate vibrations is paramount. Excessive vibrations can lead to material fatigue, operational inefficiency, and catastrophic failures. Industries require a sophisticated, accurate, and versatile tool to design…
  • College: College of Engineering (COE)
  • Inventors: Menq, Chia-Hsiang; Yang, Been-Der
  • Licensing Officer: Zinn, Ryan

AI Software for Complex NMR Spectra Analysis
TS-062576 — The Need Like a molecular “fingerprint”, NMR spectra provide valuable insights into the properties and structures of molecular compounds. However, analyzing and interpreting NMR spectra is inherently challenging as comprehensive and explicit identification of a compound is tedious and t…
  • College: College of Arts & Sciences
  • Inventors: Li, Da-Wei; Bruschweiler, Rafael
  • Licensing Officer: Panic, Ana

AI Software for Complex NMR Spectra Analysis
TS-062574 — The Need Like a molecular “fingerprint”, NMR spectra provide valuable insights into the properties and structures of molecular compounds. However, analyzing and interpreting NMR spectra is inherently challenging as comprehensive and explicit identification of a compound is tedious and t…
  • College: College of Arts & Sciences
  • Inventors: Li, Dawei "Dawei"; Bruschweiler, Rafael
  • Licensing Officer: Panic, Ana

Visual Function Mapping Technology: Enhancing Vision Care and Diagnostics
TS-062335 — The Need: In the field of ophthalmology and vision care, there is a critical need for accurate and comprehensive measurements of visual function over the entire visual field. Conditions such as glaucoma, age-related macular degeneration (AMD), diabetes, stroke, pituitary disease, brain tumors, and n…
  • College: College of Arts & Sciences
  • Inventors: Lu, Zhong-Lin; Lesmes, Luis; Xu, Pengjing "PJ"; Yu, Deyue
  • Licensing Officer: Dahlman, Jason "Jay"

Solving Sustainability Challenges for Local Communities
TS-062254 — The Need: In today's interconnected and globalized world, understanding and measuring wealth across regions is of paramount importance. Traditional measures of wealth often overlook the complexities of open borders, population flows, and inter-dependence between capital stock and population dyna…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Jones, Mackenzie
  • Licensing Officer: Panic, Ana

3DScope: Detecting 3D Model Clones
TS-057129 — Algorithm for extracting 3D models, indexing them using a value-insensitive normalization algorithm, and comparing the model indexes to detect cloned 3D models.
The unauthorized copying of 3D models robs designers of property, reduces innovation going into the creation of 3D models, creates liability for entities unknowingly using copied models, and indicates a lapse in IP security. With the vast amount of 3D assets in use, it is infeasible for humans to …
  • College: College of Engineering (COE)
  • Inventors: Zuo, Chaoshun; Lin, Zhiqiang
  • Licensing Officer: Mess, David

Finding rare events by knowing where NOT to look
TS-051417 — Traditional regression analysis has been a staple in predicting cause-effect relationships. Counltess industries use these methods to predict rare events, from economic issues to cancer research, causality is often a desired result. Given the vast amount of potential variables it sometimes becomes…
  • College: College of Arts & Sciences
  • Inventors: Melamed, David; Schoon, Eric
  • Licensing Officer: Hampton, Andrew

Point Prognostics: Closed Loop Particle Forecasting Platform for Decision Support and System Prognostics
TS-049903 — A scalable, adaptive computational platform (software) that performs accurate, predictive computer simulations in less time, with the end goal of supporting a decision-making agency
A report by IOT Analytics evaluated the predictive maintenance (PdM) market at $1.5 billion in 2016 and anticipated a growth of 39% annually to $10.96 billion by 2022. Particle methods (broadly known as "Monte Carlo'' methods, or, MC) are a class of computational algorithms used in Pd…
  • College: College of Engineering (COE)
  • Inventors: Kumar, Mrinal; Yang, Chao "Chao"
  • Licensing Officer: Zinn, Ryan

Machine-Learning Algorithm for Improved Speech Intelligibility in Noise
TS-042266 — A monaural machine-learning algorithm for classifying time-frequency units in an unknown signal, which results in marked speech-intelligibly improvements in noisy signals.
A primary complaint of hearing-impaired (HI) listeners is poor speech recognition in background noise. This issue can be quite debilitating and persists despite considerable efforts to improve hearing technology. Despite considerable effort, monaural (single-microphone) algorithms capable of incre…
  • College: College of Arts & Sciences
  • Inventors: Healy, Eric; Vasko, Jordan
  • Licensing Officer: Dahlman, Jason "Jay"

Emergency Response Tool for Industrial Facilities
TS-041844 — Artificial intelligence software for making risk-informed decisions to prevent and mitigate emergencies.
No solutions exist for predicting the likelihood of future undesirable consequences across various industrial settings. The lack of these solutions subjects personnel, the public, and the environment to potentially catastrophic consequences. Essential services such as power plants, pump stations,…
  • College: College of Engineering (COE)
  • Inventors: Yilmaz, Alper; Ajam Gard, Nima; Aldemir, Tunc; Denning, Richard; Lee, Ji Hyun
  • Licensing Officer: Zinn, Ryan

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