# of Displayed Technologies: 9 / 9

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Automated Plant DNA Extraction for Portable Genomic Sequencing
TS-063963 — The Need In the dynamic realm of space exploration, the imperative to sustain life during extended missions places a critical demand on understanding the impact of spaceflight on plant growth. Traditional DNA sequencing methods employed by NASA fall short when dealing with plant material, necessita…
  • College: College of Engineering (COE)
  • Inventors: Brozovich, Cassidy; Ling, Peter; Tkach, Chris
  • Licensing Officer: Randhawa, Davinder

Advanced AAV Gene Therapy Characterization Technique
TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …
  • College: College of Arts & Sciences
  • Inventors: Wysocki, Vicki; Cleary, Sean; Du, Chen
  • Licensing Officer: Willson, Christopher

Fluorescent probes for intracellular RNA tracking
TS-062554 — The Need: Intracellular RNA fluorescence labeling is a crucial technique for studying cellular processes and understanding gene expression. However, the conventional MS2 labeling method using protein fusion labels can have drawbacks, such as increased mass, potential steric accessibility issues, and…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng
  • Licensing Officer: Willson, Christopher

Functional "fingerloop" DNA antisense motifs for nucleic acid targeting and detection technologies
TS-062547 — The Need: The field of molecular biology and genetic engineering faces challenges in achieving precise and accurate detection and amplification of target nucleic acid sequences. Traditional hybridization technologies suffer from the issue of mismatched targets, leading to reduced specificity and rel…
  • College: College of Arts & Sciences
  • Inventors: Lease, Richard
  • Licensing Officer: Willson, Christopher

"Flexible biomarker biofluid cell array for 2D/3D mapping of biomarker concentration levels"
TS-062483 — Measurement/detection of analytes (e.g., biomarkers) in different environments (e.g., biofluids/organs) is typically performed using a biosensor. Available bio-integrated sensors do not provide the capability to map biomarker concentrations, require a power source to function, use a limited number of electrodes, and normally can only measure a specific type of biofluid but not others. The use of glutamate mapping technology (radioactive or fluorescent ligand bound to a glutamate receptor) has been evaluated and found to require bulky/expensive medical equipment, a power source for measurement, cannot be miniaturized or integrated into a bio tissue, and require patients to be stationary during measurement.
The Need To address concerns and limitations with current biomarker detection/ measurement technologies, an alternative, cost-effective, efficient biosensing system/device capable of 2D/3D mapping the concentrations of various biomarkers in different bio environments is required. The Technology …
  • College: College of Engineering (COE)
  • Inventors: Li, Jinghua; Liu, Tzu Li; Nithianandam, Prasad
  • Licensing Officer: Ashouripashaki, Mandana

Ion Carpet-Based Surface-Induced Dissociation Device
TS-062342 — The Need In the field of mass spectrometry (MS), the study of proteins and protein complexes in their native form, known as native MS, has become crucial in understanding their structure and function. However, the current collision-induced dissociation (CID) technique used in tandem MS experiments …
  • College: College of Arts & Sciences
  • Inventors: Wysocki, Vicki; Gilbert, Joshua; Stiving, Alyssa
  • Licensing Officer: Willson, Christopher

Method and Apparatus for Contained-Electrospray for Use in Mass Spectrometry and Droplet Reactions
TS-062326 — The Need: In today's analytical landscape, there is a pressing demand for improved sensitivity in electrospray ionization (ESI) to accurately quantify diverse analytes within complex mixtures. However, this task is often hindered by varying ionization responses among different compounds, includ…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Kulyk, Dmytro
  • Licensing Officer: Willson, Christopher

Identification of Bacteria That Promote Plant Growth with Low Fertilizer Inputs.
TS-062225 — The Need: Enhancing Greenhouse Ornamental Crop Production with Plant Growth Promoting Rhizobacteria (PGPR) In the competitive and environmentally-conscious market of greenhouse ornamental crop production, the need for sustainable and efficient cultivation methods has become increasingly paramount. …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Jones, Michelle; Chapin, Laura; Nordstedt, Nathan; South, Kaylee
  • Licensing Officer: Dahlman, Jason "Jay"

Real-Time Quadruplex Priming Amplification (QPA) for Nucleic Acid Amplification and Quantification
TS-014824 — An enhanced nucleic acid amplification system that is more efficient and cost-effective than conventional polymerase chain reaction methods.
Identification of a particular nucleic acid is desirable in the use of diagnostic and forensic applications. However, often the target nucleic acid sequence may only be a small portion of the DNA or RNA in question so that it might be difficult to detect the presence of the target sequence using p…
  • College: College of Arts & Sciences
  • Inventors: Kankia, Besik
  • Licensing Officer: Willson, Christopher

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