TS-067160 — The Need Due to the unparalleled ability of Mass spectrometry (MS) to identify and quantify substances at the molecular level it is an indispensable tool in various industries, from pharmaceuticals and forensics to environmental monitoring and materials science. However, the power of MS is often hi…

TS-067158 — The Need Mass spectrometry (MS) is used across a wide range of applications for detection of various chemical analytes such as drug metabolites, pesticides, food adulterants, and natural product extracts. Recent developments have transformed MS into an all-purpose technique for in-situ and real-tim…

TS-066772 — The Need Biofilms, particularly dental plaque-biofilms, are communities of microorganisms encased in a slimy extracellular polymeric substance (EPS) that adhere to surfaces or neighboring microorganisms. These biofilms are responsible for various infectious diseases, including oral diseases such as…

TS-066752 — In today's fast-paced commercial and scientific environments, there is an increasing demand for precise and efficient analytical techniques capable of handling complex mixtures with diverse physicochemical properties. Existing ionization techniques like Electrospray Ionization (ESI) and Atmosp…

TS-066233 — Protein analysis is foundational to understanding human physiology and is helpful for basic research, diagnosis, guiding treatment, and monitoring of human disease. There are several widely used platforms for evaluating protein function. The primary tools used in protein analysis on cells and tissues include antibody/aptamer, fluorescent detection systems, and mass spectrometry.

TS-065892 — The Need The microscopic worm C. elegans is a model animal studied in more than 1500 biological and medical research laboratories worldwide due to its genetic manipulability and optical transparency. In C. elegans research, the manual process of picking worms between plates presents a significant …

TS-065847 — The Need: In today's world, rapid and accurate detection of bacterial pathogens is crucial for safeguarding public health and animal well-being. With the emergence of diseases transmitted by ticks and the increasing importance of understanding vector-borne infections, there's a pressing need…

TS-065846 — The Need: With the persistent threat of avian diseases, ensuring the health and safety of turkey populations is of utmost importance to the poultry industry. Traditional methods of disease prevention have limitations, necessitating a technology that can reliably produce Specific Pathogen Free (SPF) …

TS-065845 — The Need: In the realm of biotechnology, the challenge of synthesizing enzymes, pharmaceuticals, and fine chemicals efficiently is paramount. However, the presence of multiple proteases secreted by Bacillus subtilis 168 during growth stages poses a significant obstacle to achieving optimal productio…

TS-065844 — The Need: In modern biotechnology and pharmaceutical industries, precise control over gene expression is paramount. However, conventional translation processes often lead to inefficiencies, resulting in reduced yields and compromised protein function. Meeting the demand for enhanced gene expression …

TS-065837 — The Need: In the fight against invasive species threatening our forests, rapid and accurate identification is paramount. Traditional methods for monitoring pests like the Hemlock Woolly Adelgid (HWA) and Elongate Hemlock Scale (EHS) can be time-consuming and imprecise, leading to delayed responses a…

TS-065836 — The Need: In today's agricultural landscape, precise identification and monitoring of pest damage are paramount for maintaining crop health and maximizing yields. Traditional methods often fall short in accurately assessing and addressing the impact of pests like the Elm Zigzag Sawfly (Aproceros…

TS-065457 — The Need: In the realm of therapeutic development, there's a pressing need for precise targeting of dysregulated ribonucleoprotein (RNP) complexes to combat various diseases, particularly neurodegenerative disorders like ALS, Alzheimer’s, and Huntington’s diseases. Traditional metho…

TS-065456 — The Need In modern biological research, there is a pressing demand for technologies that enable precise mapping of RNA-protein interactions within Ribonucleoprotein (RNP) complexes. Traditional methods often lack the capability to pinpoint these interactions at the level of secondary structure moti…

TS-065455 — The Need: In modern biotechnology and biomedical research, there is an escalating demand for efficient tools that can accurately detect and analyze specific RNA sequences. The ability to precisely target and identify RNA molecules, particularly U-rich sequences, is crucial for various applications s…

TS-065454 — The Need: As agriculture faces increasing challenges from plant pathogens, rapid and accurate detection methods are crucial to safeguarding crop yields and ensuring food security. Traditional methods of pathogen detection often suffer from delays in diagnosis, leading to significant crop damage and …

TS-064824 — The Need In the pharmaceutical industry, the synthesis of complex organic substrates is crucial for the development of life-saving medications. However, traditional metal-catalyzed coupling reactions often face significant challenges when applied to these complex substrates, leading to high failure…

TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year. The Need Developing drugs for cance…

TS-064271 — The Need In the rapidly advancing landscape of life sciences, researchers and biotech companies face an escalating demand for reliable and versatile cell lines. The need for a specialized cell line that combines adaptability, reproducibility, and ease of use is paramount in accelerating breakthroug…

TS-063697 — Controlled Protein Release Over a Broad Range of Temperatures

TS-063194 — The Need In the medical and healthcare arena, force plate technology is frequently relied upon for evaluating a patient’s ability to meet normal human standards when performing different physical activities and determining the presence of limitations in mechanistic-type behaviors due to age, …

TS-062968 — A novel method of creating catalytic material containing paired Lewis acids in combination with alkyl-metal precursors for improving the production of materials used in agricultural, chemical, and other commercial/industrial applications/processes.

TS-062967 — Novel method capable of using alkyl tin compounds to generate Lewis acid zeolite Sn-Beta.

TS-062844 — Road departure is a serious threat to vehicle safety and can result in fatal accidents. To prevent road departure, some vehicles are equipped with a road departure mitigation system that can detect when a vehicle is about to leave the road and take corrective actions. However, there is a need for …

TS-062834 — Road departure can be extremely dangerous for vehicles. Some vehicles are equipped with road departure mitigation systems to prevent this from happening. However, testing these systems can be difficult and costly, as it involves crashing vehicles into roadside objects. The concrete divider surr…

TS-062797 —

TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …

TS-062554 — The Need: Intracellular RNA fluorescence labeling is a crucial technique for studying cellular processes and understanding gene expression. However, the conventional MS2 labeling method using protein fusion labels can have drawbacks, such as increased mass, potential steric accessibility issues, and…

TS-062547 — The Need: The field of molecular biology and genetic engineering faces challenges in achieving precise and accurate detection and amplification of target nucleic acid sequences. Traditional hybridization technologies suffer from the issue of mismatched targets, leading to reduced specificity and rel…

TS-062494 — A novel magnetohydrodynamic (MHD) pump-based thermal management system design where integration of the cooling apparatus using electronic circuit interconnections achieves improved thermal management at a lower cost.

TS-062483 — Measurement/detection of analytes (e.g., biomarkers) in different environments (e.g., biofluids/organs) is typically performed using a biosensor. Available bio-integrated sensors do not provide the capability to map biomarker concentrations, require a power source to function, use a limited number of electrodes, and normally can only measure a specific type of biofluid but not others. The use of glutamate mapping technology (radioactive or fluorescent ligand bound to a glutamate receptor) has been evaluated and found to require bulky/expensive medical equipment, a power source for measurement, cannot be miniaturized or integrated into a bio tissue, and require patients to be stationary during measurement.

TS-062433 — The Need: Understanding the intricate functions of the K-Ras protein is crucial in combating various types of human cancer. However, the lack of detailed atomic-level information has hindered progress in this area, leaving significant gaps in our comprehension of its roles in health and disease. Th…

TS-062405 — Primary Poultry Satellite cells

TS-062404 — Pimary Avian Breast Muscle Satellite Cells

TS-062403 — Primary Chicken breast muscle satellite cells

TS-062351 — The Need: In today's fast-paced world, advancements in scientific research and medical breakthroughs are critical to addressing pressing global challenges. The study of bats and their unique biology has become increasingly important due to their potential role as reservoirs for zoonotic diseases…

TS-062349 — The Need In the veterinary field, there is a crucial need for accurate and specific diagnostic tests to identify and distinguish between Anaplasma platys (Apl) and other related pathogens like Anaplasma phagocytophilum (Aph). Current diagnostic methods lack specificity, leading to challenges in dif…

TS-062346 — The ability to rapidly identify and determine virus titer is of utmost importance in numerous biomedical applications, ranging from gene editing to pharmaceutical and vaccine development. In the context of lentiviruses, which are widely used for cell reprogramming in immunotherapies, knowing the e…

TS-062342 — The Need In the field of mass spectrometry (MS), the study of proteins and protein complexes in their native form, known as native MS, has become crucial in understanding their structure and function. However, the current collision-induced dissociation (CID) technique used in tandem MS experiments …

TS-062340 — The Need There is a commercial need for an advanced ionization and analysis technology that can effectively and rapidly detect and analyze organic compounds, including both polar and non-polar ones, in various matrices. The current challenges in existing ambient mass spectrometry (MS) methods inclu…