TS-074316 — Pre‑Launch Start‑Up Opportunity: Seeking Business Leads ElectroTag is a multiplex diagnostics platform that enables simultaneous measurement of multiple disease‑associated proteins from a small patient sample. The system replaces conventional color‑based labels with mass‑encoded peptide tags that are read by mass spectrometry, delivering higher analytical specificity and a clear path to expanding from small to large biomarker panels while maintaining streamlined workflows.

TS-074315 — Pre‑Launch Start‑Up Opportunity ElectroFuel‑MES offers an electrified bioprocess that turns heterogeneous food and agricultural waste streams into higher‑value fuels and chemicals, providing an energy‑efficient alternative to anaerobic digestion and thermochemical treatment.

TS-074297 — Gas turbine systems are typically optimized for a narrow operating point, leading to efficiency penalties during off‑design operation. Existing variable-geometry solutions rely on mechanically actuated components that add complexity, incur performance losses, and face durability challenges in hi…

TS-074295 — Many applications require compact, long‑lived power sources that can operate reliably for years without maintenance, battery replacement, or recharging. This is particularly true for remote sensors, implantable medical devices, space systems, and defense or industrial monitoring deployed in hars…

TS-074278 — Millions of individuals with mobility impairments lack practical, scalable assistance for gait rehabilitation and daily ambulation. Existing powered exoskeletons are often heavy, expensive, complex to don, and poorly suited for long-duration or everyday use. Passive walkers and orthotic devices pr…

TS-074271 — Predictable, chemistry level control of biodegradable polymer behavior to simplify development, improve reproducibility, and enable differentiated biomedical products.

TS-074268 — Real-time and free-breathing MRI applications, particularly in cardiovascular imaging, require high temporal resolution to capture rapid physiological dynamics. However, optimal temporal resolution is often patient- and application-specific and may not be known before the scan. Existing Cartesian …

TS-074248 — Nitrogen oxides (NOx) emissions remain a major regulatory and environmental challenge for power generation, industrial combustion, and waste incineration. The dominant abatement technology, selective catalytic reduction (SCR), relies on ammonia or urea, introducing safety, cost, and operational co…

TS-074223 — Researchers at The Ohio State University have developed a self‑regulating manufacturing platform for porous polymer meshes that integrates mesh formation and drug loading in a single step, enabling controlled local delivery from implantable materials.

TS-074219 — This early‑stage electrochemical platform enables integrated CO₂ capture and permanent mineralization while supporting lower‑energy hydrogen production, offering a research‑driven pathway toward energy system decarbonization.

TS-074218 — This HIV-focused technology introduces a novel strategy for engaging conserved viral biology that is not directly addressed by existing antiretroviral classes. By expanding the range of actionable HIV mechanisms, the approach creates new opportunities for therapeutic discovery, combination strategies, and next‑generation intervention concepts. The technology is designed to complement current HIV treatment paradigms while supporting diversification of long‑term antiviral pipelines.

TS-074217 — An OSU innovation may enable farmers to actively manage water at the field scale to improve crop performance, input efficiency, and operational profitability.

TS-074216 — Reducing debris‑related drainage failures while lowering maintenance risk and lifecycle costs for transportation infrastructure owners.

TS-074203 — Objective, repeatable evaluation of dishwashing tools and processes to strengthen sanitation outcomes and product performance.

TS-074168 — Electrification trends in aerospace, transportation, and industrial systems demand electric machines with substantially higher power density, efficiency, and reliability. Conventional motor and generator architectures struggle at high frequencies and power levels due to skin and proximity losses, …

TS-074143 — Across desalination, water reuse, and other separation markets, operators continue to face a fundamental tradeoff between membrane permeability and selectivity. Existing commercial polyamide membranes often sacrifice water flux to achieve high salt rejection, driving higher energy consumption, inc…

TS-074101 — A natural microbial solution that supports consistent rooting, stronger early growth, and improved plant quality in greenhouse ornamentals.

TS-074095 — Hybrid and electrified vehicles face increasing pressure to simultaneously reduce fuel consumption and tailpipe emissions, particularly during transient operating conditions such as cold start. Conventional rule-based or static control strategies struggle to optimally manage the tradeoffs among en…

TS-074084 — A novel polymer-assisted dry transfer method enables high-quality, large-area integration of molecular beam epitaxy (MBE)-grown 2D materials onto arbitrary substrates, unlocking scalable manufacturing of next-generation electronic, optoelectronic, and quantum devices.

TS-074050 — As batteries are pushed toward faster charging and higher power operation, conventional electrode architectures struggle to deliver their full theoretical capacity. Dense electrodes often suffer from poor ion and electron transport, leading to large capacity losses at high charge and discharge rat…

TS-074049 — Commercial and industrial HVAC systems face growing pressure to reduce energy consumption while delivering precise humidity control, particularly in hot and humid climates. Conventional desiccant and vapor‑compression systems require high regeneration temperatures, waste low‑grade heat, and st…

TS-074040 — Unlocking a low‑energy, scalable biological platform for degrading for reducing bioplastic and microplastic accumulation. Overview Plastic and bioplastic residues continue to build up in water, soil, and composting systems, creating long‑term environmental and regulatory challenges. Althoug…

TS-073966 — Cities and large campuses struggle to provide cost‑effective, low‑emission mobility for short trips and first/last‑mile connections. Fixed‑route buses are often underutilized in low‑demand areas yet insufficient during peak demand, while single‑vehicle autonomous shuttles lack scalabil…

TS-073942 — Conventional electrochromic devices rely on ion intercalation, electrolyte layers, and complex multilayer stacks, which increase cost, limit durability, slow switching, and raise environmental and safety concerns (particularly due to lithium-containing components). These constraints hinder broader…

TS-073932 — DEEP Phaser enables fully automated, expert level phase correction to improve NMR data quality, consistency, and throughput across routine and high-volume workflows. Problem Overview Accurate phase correction is essential for reliable NMR interpretation and quantitative analysis. Despite its impo…

TS-073930 — Many industrial gas–solid reactions, such as ironmaking, chemical looping, and other redox-based processes, are fundamentally constrained by thermodynamic equilibrium in conventional reactor designs. Single-inlet/single-outlet reactors force tradeoffs between gas conversion and solid conversion,…

TS-073910 — Ferroelectric Hf₀.₅Zr₀.₅O₂ is a strategically important material for electronics, photonics, and energy applications, but its ferroelectric phase has historically been accessible only in ultrathin films or expensive single crystals. These approaches rely on high temperatures, complex dep…

TS-073895 — The Need In the rapidly evolving field of biotechnology and pharmaceuticals, there is a critical need for efficient delivery mechanisms to transport therapeutic agents directly into cells. Cell-penetrating peptides (CPPs) initially were considered a potential solution. Short sequences of amino acid…

TS-073880 — Industrial CO₂ electroreduction remains limited by high energy input, poor selectivity, and low formation rates of valuable multi‑carbon products. Conventional copper catalysts often favor hydrogen evolution or low‑value C₁ products such as methane, while catalysts that improve selectivity…

TS-073844 — Current communication systems often struggle with efficiency and reliability, especially in noisy environments and varying relay positions. Traditional methods focus on exact message reconstruction, which can be resource-intensive and less effective for real-time applications. There is a growing n…

TS-073842 — In the era of 6G and beyond, efficient and robust communication of multimodal messages (text and images) is critical, especially in resource-constrained environments. Current methods struggle with noise robustness and codeword length, leading to inefficiencies and increased error rates. There is a…

TS-073841 — Current federated learning (FL) systems face significant challenges in efficiently aggregating model updates over wireless networks, especially in environments with diverse data and varying channel conditions. There is a critical need for a solution that enhances bandwidth efficiency, personalizat…

TS-073818 — Autonomous and advanced driver-assistance systems require extensive testing across rare, hazardous, and edge-case scenarios to ensure safety and regulatory readiness. Existing approaches (pure simulation, hardware-in-the-loop, proving grounds, or public-road testing) each suffer from tradeoffs in …

TS-073810 — Next-generation power electronics demand materials that can support ultra-high breakdown voltages, low leakage currents, and scalable manufacturing. While β-Ga₂O₃ is highly attractive for these applications, device performance has been limited by the lack of high-quality, thick drift layers w…

TS-073809 — High-sensitivity detection in the mid-wave and long-wave infrared (MWIR/LWIR) remains constrained by detector noise, limited gain, and manufacturing challenges. While HgCdTe avalanche photodiodes can deliver excellent performance, they suffer from high cost, low yield, and limited manufacturabilit…

TS-073768 — Electrified and hybrid vehicle powertrains are increasingly complex, integrating mechanical, electrical, thermal, and emissions subsystems with both continuous and discrete decision variables. Existing energy management and co‑optimization approaches typically rely on simplified models, sequenti…

TS-073740 — Magnesium is the lightest structural metal and offers compelling weight‑reduction potential for transportation and other markets. However, broader adoption has been limited by the poor room‑temperature formability, modest strength, and narrow processing windows of conventional magnesium extrus…

TS-073732 — Advanced lithium-ion batteries increasingly adopt metallized polymer current collectors to improve safety by mitigating internal short circuits and thermal runaway. However, these collectors are inherently difficult to join to each other and to battery tabs using conventional manufacturing methods…

TS-073717 — Spiking Neural Networks (SNNs) promise ultra-low-power, low-latency AI for edge and neuromorphic computing, but their adoption is constrained by fundamental training challenges. SNN performance is highly sensitive to how training data are collected (e.g., lighting, sensor settings, noise), leading…

TS-073712 — Advanced quantum technologies, cryogenic sensors, and space instrumentation increasingly require reliable, compact cooling below 1 K. Today’s sub-Kelvin refrigeration relies heavily on dilution refrigerators and gas-gap thermal switches that are complex, slow, mechanically fragile, and dependent…