Non-Contact Magnetocardiography for Measuring Cognitive Workload
TS-067810 — Work environments and other brain-intensive activities impose high demands on the cognitive and cerebral resources required to process vast amounts of information. This high demand can expose individuals to cognitive overload, which can be dangerous for their health and lead to errors and accidents.…
- College: College of Engineering (COE)
- Inventors: Kiourti, Asimina; Zhu, Keren
- Licensing Officer: Randhawa, Davinder
A Non-Destructive Quality Control Test for Organic Coatings in Food Can Applications
TS-067800 — This technology is an electrical impedance test (EIT) for evaluating the integrity of the enamel coating found on the interior surface of canned foods.
Fruits and vegetables used in canning are picked at peak freshness, ensuring the best flavor and nutrient quality. Because canning preserves nutrients, canned foods can be as nutritious as fresh and frozen foods. The amount of minerals, fat-soluble vitamins, protein, fat, and carbohydrates remains r…
- College: College of Engineering (COE)
- Inventors: Frankel, Gerald "Jerry"; Kosanam, Koushik
- Licensing Officer: Zinn, Ryan
Neonatal Blood Vessel Locator for Vascular Access Procedures
TS-067796 — A handheld device for identifying preterm blood vessels in neonatal ICU.
Over 300,000 preterm births in the United States occur annually, representing 10.5% of all live births. Most preterm births occur spontaneously, but some result from medical conditions like infections or pregnancy complications requiring early labor induction or cesarean delivery. Common causes of p…
- College: College of Engineering (COE)
- Inventors: Metzler, Sandra; Bresolin, Alejandro; Crawford, Mackenzie; Fernandes, Siddharth; Hardin, Rene; Patel, Aarti; Richards, Hannah; Trainor, Dylan
- Licensing Officer: Zinn, Ryan
Methods to produce high purity tritium gas
TS-067793 — The technology is a device and method for producing high purity tritium gas by irradiating a lithium composition within a gas cell that selectively allows tritium to diffuse while blocking other byproducts, ensuring efficient and direct collection of pure tritium without extensive purification. This system is designed to enhance the purity, efficiency, and scalability of tritium production for various industrial and research applications.
The production of high purity tritium gas is critical for applications in nuclear fusion, radioluminescent devices, and scientific research. Current methods for tritium production often result in contaminants like helium and other gases, requiring additional purification processes that are costly …
- College: College of Engineering (COE)
- Inventors: Cao, Lei Raymond; Van Zile, Matthew
- Licensing Officer: Zinn, Ryan
Computational Design of Experiment Framework for Processing of Metal Alloys
TS-067792 — A software tool for optimizing the manufacturing process for metal alloys.
Metallic alloys are composed of a homogeneous mixture of two or more metals or of metals and nonmetal or metalloid elements to provide specific characteristics or structural properties. Alloys are used in many applications, such as aircraft, offshore drilling, automobiles, and others.
Obtaining t…
- College: College of Engineering (COE)
- Inventors: Alexandrov, Boian; Forquer, Matthew; Jang, Eun; Luo, Yuxiang; Stewart, Jeffrey
- Licensing Officer: Zinn, Ryan
Advanced Biopesticides and Bio Stimulants for Sustainable Crop Protection and Growth Enhancement
TS-067761 — The Need: In the face of climate change and the diminishing efficacy of conventional pest control methods, the agricultural industry is in dire need of sustainable solutions to protect and enhance crop growth. The escalating disease pressure calls for innovative technologies that can bolster a plant…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Wang, Guo-Liang; Patel, Preeti; Pei, Dehua; Storch, Cameron
- Licensing Officer: Dahlman, Jason "Jay"
A device for improving the breakdown performance of gallium oxide semiconductors
TS-067551 — Gallium Oxide (Ga2O3) is an inorganic compound with semi-conductivity properties (e.g., a large bandgap) that can be used for developing power electronics, UV photodetectors, solar cells, and sensors. βeta-Ga2O3, a polymorph, has a distinct advantage over other semiconductors that have high cri…
- College: College of Engineering (COE)
- Inventors: Dheenan, Ashok; Dhara, Sushovan; Rajan, Siddharth
- Licensing Officer: Zinn, Ryan
Optimal and Pure Leaf Classification Trees for Machine Learning (ML) Decision-Making
TS-067550 — A method to improve the performance and accuracy of ML-based decision trees.
Decision trees are popular machine learning (ML) methods used in classification and regression problems, and they have numerous applications in the real world. Various industries use decision trees to help decide strategies, investments, and operations. In addition, they are used in healthcare to he…
- College: College of Engineering (COE)
- Inventors: Allen, Theodore; Arrey, Evelyn; Booth, Matthew; Liu, Enhao; Mashayekhi, Medhi
- Licensing Officer: Zinn, Ryan
Method of repurposing spacecraft dust as an agricultural material
TS-067535 — The Need
In future decades, more people than ever will be spending time in space. Current crop production systems onboard spacecraft are not self-sustainable, relying on fertilizer and substrate materials that must be launched from Earth. These resupply missions can cost thousands of dollars per po…
- College: College of Engineering (COE)
- Inventors: Nastasi, Nicholas; Dannemiller, Karen
- Licensing Officer: Ashouripashaki, Mandana
Unlocking Hidden Opportunities: The Power of Multi-Solution Spatial Aggregation
TS-067434 — The Need
Spatial aggregation is crucial in numerous industries where data from low-level spatial units, such as census blocks, must be grouped into larger, meaningful regions. Traditional approaches often struggle with the computational complexity of these tasks and tend to focus on finding a singl…
- College: College of Arts & Sciences
- Inventors: Xiao, Ningchuan
- Licensing Officer: Dahlman, Jason "Jay"
FARMS: Streamlining Farm Transition Planning for a Secure Future
TS-067290 —
Farm transition planning is a critical yet complex process for producers, often hindered by the challenge of collecting and organizing asset information. Without a clear understanding of what assets are owned, their value, and how they are titled, farm transition planning becomes a guessing game r…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Moore, Robert; Marrison, David
- Licensing Officer: Panic, Ana
Reed Held: Precision Practice Tool for Oboists
TS-067289 — The Need
Oboists often struggle with fundamental elements of their playing, such as pitch accuracy, phrasing, and response, due to the complexity of managing the instrument as a whole. Traditional practice methods may not allow for the isolated focus necessary to correct these specific issues. Ther…
- College: College of Arts & Sciences
- Inventors: Held, Abby
- Licensing Officer: Panic, Ana
Direct Analysis of Air and Water Sensitive Material by In-Chamber Ionization Mass Spectrometry
TS-067160 — The Need
Due to the unparalleled ability of Mass spectrometry (MS) to identify and quantify substances at the molecular level it is an indispensable tool in various industries, from pharmaceuticals and forensics to environmental monitoring and materials science. However, the power of MS is often hi…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Hadad, Christopher; Lalisse, Remy; Sahraeian, Taghi; Wu, Yiying; Zheng, Jingfeng
- Licensing Officer: Panic, Ana
Co-Axial Contained Electrospray Ionization Platform for Mass Spectrometry
TS-067158 — The Need
Mass spectrometry (MS) is used across a wide range of applications for detection of various chemical analytes such as drug metabolites, pesticides, food adulterants, and natural product extracts. Recent developments have transformed MS into an all-purpose technique for in-situ and real-tim…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Burris, Benjamin "Ben"; Grooms, Alex; Heiss, Derik; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
AIDRIN (AI Data Readiness Inspector)
TS-067116 — AIDRIN (AI Data Readiness INspector) is a system designed to comprehensively evaluate datasets through a diverse range of metrics, giving an overall perspective on their readiness for AI applications.
In the contemporary digital landscape, the explosive growth in data generation has created a pressing need for efficient and scalable database systems. Traditional databases struggle with the increasing volume, variety, and velocity of data, leading to performance bottlenecks, high operational cos…
- College: College of Engineering (COE)
- Inventors: Byna, Suren; Hiniduma, Kaveen
- Licensing Officer: Zinn, Ryan
Endoscopic additive manufacturing of conductors and wireless implants
TS-067045 — The Need
Wireless implants with integrated antennas are highly desirable for diagnostic, therapeutic, and monitoring applications due to their ability to communicate directly with external devices. However, the need for major surgical incisions to implant these devices poses significant risks, incl…
- College: College of Engineering (COE)
- Inventors: Kiourti, Asimina; Dontha, Balaji; Hoelzle, David; Li, Jinghua; Moulod, Mohammad
- Licensing Officer: Randhawa, Davinder
Novel Quantitative Method to Detect Mold Growth in Buildings
TS-066963 — The Need
Exposure to mold in homes costs billions of dollars every year. Exposure is particularly harmful to the 8% of the United States population that suffers from asthma; a leading cause of disability in children. Currently, odor, visible mold growth, and dampness are the best indicators of mold…
- College: College of Engineering (COE)
- Inventors: Dannemiller, Karen; Balasubrahmaniam, Neeraja; Bope, Ashleigh
- Licensing Officer: Ashouripashaki, Mandana
Dust Analysis: A Novel Approach to Monitoring Viral Spread
TS-066962 — The Need
Viral disease surveillance (e.g. influenza, SARS-CoV-2) in high-risk settings faces several challenges, such as asymptomatic carriers, incomplete reporting, resource limitations, and delayed diagnosis of traditional swab test methods. These challenges could allow a virus to silently spread…
- College: College of Engineering (COE)
- Inventors: Dannemiller, Karen; Faith, Seth; Hull, Natalie; Nastasi, Nick; Renninger, Nicole
- Licensing Officer: Ashouripashaki, Mandana
Smartphone Detection Kit for Airborne Formaldehyde and Allergens
TS-066960 — The Need
Indoor air can be polluted by various sources, including building materials, furniture, cleaning products, and even people. Exposure to these resulting contaminants and allergens can lead to a variety of health problems, such as respiratory irritation, allergies, and even cancer. It is cur…
- College: College of Engineering (COE)
- Inventors: Dannemiller, Karen; Parquette, Jonathan; Qin, Rongjun
- Licensing Officer: Ashouripashaki, Mandana
Color Correction System for Accurate Colorimetric Smartphone Measurements
TS-066957 — The Need
Colorimetric tests and remote image analysis are used in a wide range of industrial and medical applications. Digital image-based measurements made with smartphones are a promising platform to quantify colors at low cost, but suffer from inconsistency and errors caused by lens quality, sen…
- College: College of Engineering (COE)
- Inventors: Dannemiller, Karen; Panescu, Jenny; Qin, Rongjun; Song, Shuang; Zhang, Guixiang
- Licensing Officer: Ashouripashaki, Mandana
Unveiling the Nanoscale: Breakthrough Analytical Speed of Real-Time Super-Resolution Microscopy and Beyond
TS-066926 — This Ohio State University software innovation offers groundbreaking analytical speed and automation of Single-Molecule Localization Microscopy (SMLM) as well as analysis of 3D data and images extending beyond the field of microscopy. Our technology offers real-time spatial analysis in continuous and discrete space, enabling unprecedented speed and efficiency in data processing that translates into faster decision-making, high-throughput screening capabilities, and broad applicability beyond traditional microscopy.
Single-molecule localization microscopy (SMLM) describes a family of fast-evolving, powerful imaging techniques that dramatically improve spatial resolution over standard, diffraction-limited microscopy techniques and can image biological structures at the molecular scale. SMLM can now be performe…
- College: College of Engineering (COE)
- Inventors: Soltisz, Andrew; Veeraraghavan, Rengasayee
- Licensing Officer: Zinn, Ryan
Humanized SSTR2 mAb and ADC to target SSTR2+ tumors
TS-066912 — Targeted humanized mAbs and ADCs for cancer treatment
The Liu Lab
Dr. Xiaoguang “Margaret” Liu applies her industry experience (Lonza, Merck, and Life Technologies) in cell line and process development towards her lab’s focus on targeted anti-cancer therapies including monoclonal antibodies, antibody-drug conjugates, and gene therapi…
- College: College of Engineering (COE)
- Inventors: Liu, Xiaoguang "Margaret"; Zhou, Lufang
- Licensing Officer: Schworer, Adam
Advanced Sensor Housing for Environmental Monitoring in Precision Agriculture and Beyond
TS-066793 — The Need
In agriculture, the accurate measurement of gasses such as nitrous oxide (N2O) and nitrogen oxides (NOx) is crucial for optimizing fertilizer use, minimizing greenhouse gas emissions, and reducing air pollution. Current monitoring technologies are often expensive, complex, and not suitable…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Khanal, Sami; Bevers, Noah; Shearer, Scott; Tkach, Chris
- Licensing Officer: Dahlman, Jason "Jay"
Small Molecule USP30 Inhibitors for the Treatment and Prevention of Cardiomyopathy
TS-066773 — The Need
Cardiomyopathy, a disease of the heart muscle, poses significant public health challenges due to its diverse causes, symptoms, and potential complications, including heart failure and arrhythmias. With cardiomyopathy often induced by drugs, such as anthracyclines used in chemotherapy, ther…
- College: College of Medicine (COM)
- Inventors: Sun, Nuo; Krigman, Judith; Yang, Mingchong; Zhang, Ruohan
- Licensing Officer: Willson, Christopher
Biofilm Detachment Monitoring for Enhanced Oral Health Solutions
TS-066772 — The Need
Biofilms, particularly dental plaque-biofilms, are communities of microorganisms encased in a slimy extracellular polymeric substance (EPS) that adhere to surfaces or neighboring microorganisms. These biofilms are responsible for various infectious diseases, including oral diseases such as…
- College: College of Medicine (COM)
- Inventors: Stoodley, Paul; Gloag, Erin
- Licensing Officer: Willson, Christopher
Innovative Biomarker Technology for Detecting and Treating Endothelial Injury in Neurological Disorders
TS-066771 —
Endothelial injury is a significant pathological mechanism underlying various neurological disorders, including neurodegenerative, neuroinflammatory, and cerebrovascular diseases. Current clinical and research settings lack reliable biomarkers to detect or measure endothelial injury in the human C…
- College: College of Medicine (COM)
- Inventors: Al Tarawneh, Rawan
- Licensing Officer: Willson, Christopher
Advanced Dual-Layer Compositions for Enhanced Delivery and Stability of Biologically Active Agents
TS-066770 — The Need
In the realm of human and mammalian health, delivering biologically active components that are sensitive to moisture or other environmental factors has posed a significant challenge. Traditional methods, such as encapsulation or use of desiccants, often fall short in ensuring stability and…
- College: Office of Business and Finance
- Inventors:
- Licensing Officer: Dahlman, Jason "Jay"
Advanced Mass Spectrometry Hybrid Ionization Technology for Comprehensive Molecular Analysis
TS-066752 —
In today's fast-paced commercial and scientific environments, there is an increasing demand for precise and efficient analytical techniques capable of handling complex mixtures with diverse physicochemical properties. Existing ionization techniques like Electrospray Ionization (ESI) and Atmosp…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Damale, Purva; Grooms, Alex; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Cell-Penetrating Peptides: Revolutionizing Intracellular Delivery
TS-066751 —
In the rapidly evolving field of biotechnology and pharmaceuticals, there is a critical need for efficient delivery mechanisms to transport therapeutic agents directly into cells. Traditional methods face challenges with membrane impermeability and degradation of therapeutic compounds, limiting th…
- College: College of Arts & Sciences
- Inventors: Pei, Dehua
- Licensing Officer: Dahlman, Jason "Jay"
Innovative Small Molecule Inhibitors for Effective Treatment and Prevention of Coronavirus Infections
TS-066750 —
The ongoing COVID-19 pandemic, caused by the SARS-CoV-2 virus, has significantly impacted global health and economies. Despite vaccine efforts, issues such as vaccine hesitancy, delays in distribution, and emerging variants have highlighted the need for effective therapeutic interventions. These i…
- College: College of Veterinary Medicine
- Inventors: Sharma, Amit; Li, Pui-Kai "Tom"; Xing, Enming
- Licensing Officer: Willson, Christopher
Revolutionary Modular Nuclear Reactor Core for Space Exploration
TS-066252 — Rotating Fuel Core with Fuel Strip(s) ("ROFFUS") is an innovative modular nuclear reactor core designed to provide reliable and scalable power for advanced space missions.
Future space missions require dependable, high-output energy sources to support operations such as material processing, transportation, and thermal conditioning, particularly in challenging environments like the lunar poles where sunlight is scarce.
This advanced nuclear reactor core features a…
- College: College of Engineering (COE)
- Inventors: Smidts, Carol; Aldemir, Tunc; Cao, Lei Raymond; Horack, John; Khafizov, Marat
- Licensing Officer: Zinn, Ryan
Advanced Sensor Arrays for Precise Gas Identification and Analysis
TS-066250 — A cutting-edge sensor system featuring p-n junctions in MOS materials for accurate detection and identification of gases.
In various industries, there is a growing demand for highly selective and sensitive gas sensors capable of accurately identifying specific gases within complex mixtures, addressing challenges in environmental monitoring, industrial safety, and healthcare diagnostics.
This innovative sensor syst…
- College: College of Arts & Sciences
- Inventors: Dutta, Prabir; Govindhan, Maduraiveeran; Mondal, Suvra; Sun, Chenhu
- Licensing Officer: Zinn, Ryan
Revolutionary NO Sensor for Highly Selective and Sensitive Gas Detection
TS-066249 — A novel sensor leveraging WO3 and Cr2O3 for selective NO detection in harsh environments and breath analysis with high sensitivity at ppb levels.
There is a critical demand for advanced gas sensors capable of selectively detecting nitric oxide (NO) in diverse applications such as environmental monitoring, industrial processes, and medical diagnostics, particularly in challenging environments with interfering gases like carbon monoxide (CO).…
- College: College of Arts & Sciences
- Inventors: Dutta, Prabir; Govindhan, Maduraiveeran; Mondal, Suvra; Sun, Chenhu
- Licensing Officer: Zinn, Ryan
Metal oxide-based resistive type sensor for the detection of carbon monoxide at room temperature
TS-066246 — Our innovative CO sensor utilizes hydrated ruthenium oxide to detect carbon monoxide within a gas mixture with high sensitivity and selectivity at temperatures ranging from 25°C to 300°C.
Reliable and low-cost CO sensors with high sensitivity and selectivity are essential for environmental safety and industrial control, particularly to monitor combustion environments, automotive emissions, and various industrial processes, ensuring compliance with regulations and minimizing health …
- College: College of Arts & Sciences
- Inventors: Dutta, Prabir; Adeyemo, Adedunni
- Licensing Officer: Zinn, Ryan
Compact High-Temperature Solid-State Potentiometric Oxygen Sensor
TS-066235 —
Oxygen sensors are crucial for monitoring oxygen levels in combustion and industrial processes, but current sensors require complex plumbing for reference gas, limiting their placement and operational temperature range. There is a pressing need for a robust, high-temperature oxygen sensor that is …
- College: College of Arts & Sciences
- Inventors: Dutta, Prabir; Akbar, Sheikh; Ramasamy, Ramamoorthy; Routbort, Jules; Singh, Dileep; Spirig, John
- Licensing Officer: Zinn, Ryan
BDAMPER: Advanced Application Software for Dynamic Analysis and Design of Friction Damper Structures
TS-066234 —
In the realm of rotating machinery and structural engineering, the need to manage and mitigate vibrations is paramount. Excessive vibrations can lead to material fatigue, operational inefficiency, and catastrophic failures. Industries require a sophisticated, accurate, and versatile tool to design…
- College: College of Engineering (COE)
- Inventors: Menq, Chia-Hsiang; Yang, Been-Der
- Licensing Officer: Zinn, Ryan
3D Object-based Segmentation-based Quantification of Spatial Protein Organization (OBS3D)
TS-066233 — Protein analysis is foundational to understanding human physiology and is helpful for basic research, diagnosis, guiding treatment, and monitoring of human disease. There are several widely used platforms for evaluating protein function. The primary tools used in protein analysis on cells and tissues include antibody/aptamer, fluorescent detection systems, and mass spectrometry.
Colocalization analysis is the current standard technique for assessing spatial association of co‐labeled proteins in cells using multicolor immunofluorescence images. However, these tools are limited because multiple antigens nearby exhibit overlapping staining, which leads to inaccurate analys…
- College: College of Engineering (COE)
- Inventors: Veeraraghavan, Rengasayee
- Licensing Officer: Zinn, Ryan
Innovative Solutions for Cell Viability and Targeted Delivery
TS-066100 — Research tool to transfect cells ex vivo using electroporation through electrospun core-shell fibers for research applications
The Need:
Conventional electroporation methods often result in low cell viability due to heat generation, especially when working with primary cells. These methods also face challenges with non-specific transport of molecules, high vector integration rates leading to mutagenesis, and inefficacy in …
- College: College of Engineering (COE)
- Inventors: Gallego Perez, Daniel; Das, Devleena; Duarte Sanmiguel, Silvia; Higuita Castro, Natalia
- Licensing Officer: Willson, Christopher
A Cybersecurity Vulnerability Prioritization System Including Identifying "Super-Critical" Vulnerabilities, predicting "Dark Host" Vulnerabilities, and Addressing Economic Costs
TS-066063 — Our cybersecurity vulnerability maintenance system stands as a pillar of modern security strategy, transforming reactive security measures into a preemptive defense mechanism. This integration of technology and economics ensures that your most critical assets are protected efficiently and effectively, making it an invaluable tool for any organization serious about security.
In today’s hyper-connected world, the escalation in cyber threats poses significant risks to organizational data and systems. Vulnerabilities within network infrastructures can lead to massive security breaches, as demonstrated by incidents like the 2017 Equifax hack. Effective vulnerability…
- College: College of Engineering (COE)
- Inventors: Allen, Theodore; Liu, Enhao
- Licensing Officer: Zinn, Ryan
SimulationAI -- AI-Enabled Software Solution for Physics-Based Simulations
TS-066058 — By adopting our AI-driven solution, engineering teams can achieve more in less time, push the boundaries of innovation, and significantly cut down costs, all while maintaining or increasing the reliability and accuracy of their structural and material analysis. This is not just an evolution in FEM technology—it's a revolution.
In an era where precision and efficiency drive the success of engineering projects, the finite element method (FEM) remains indispensable but is burdened by high operational and computational costs. These costs often lead to overlooked uncertainty factors, suboptimal designs, and significant finan…
- College: College of Engineering (COE)
- Inventors: Soghrati, Soheil; vemparala, Balavignesh; Yang, Ming
- Licensing Officer: Zinn, Ryan
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