# of Displayed Technologies: 40 / 642


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European Corn Borer mating Cage
TS-065465 — The Need: The agricultural sector faces persistent challenges in controlling pests like the European Corn Borer (ECB), which can devastate corn crops, leading to significant economic losses. Traditional methods often prove inadequate, necessitating innovative solutions to combat these destructive in…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Michel, Andrew; Basnagala, Suranga
  • Licensing Officer: Dahlman, Jason "Jay"

3D-Printed Soybean Leaf
TS-065464 — The Need In modern agriculture, the ability to quickly and accurately identify diseases impacting soybean crops is critical for farmers to maintain yield and profitability. Traditional methods of disease identification can be time-consuming and imprecise, leading to potential losses. There is a cle…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Lang, Olivia; Michel, Andy
  • Licensing Officer: Dahlman, Jason "Jay"

Indolce™: Elevating Pudding to a Calming Experience
TS-065463 — The Need: In today's fast-paced world, consumers seek not just sustenance but also moments of tranquility amidst the chaos. Indolce™ meets this need by offering a decadent pudding snack infused with mood-boosting ingredients designed to soothe both the palate and the mind. With stress leve…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Melendrez Alvarez, Ronald; Choriego Marin, Rolando; Kosmerl, Erica; Miller, Celeste
  • Licensing Officer: Dahlman, Jason "Jay"

Rubber Cultivation for Increased Yield and Sustainability-The "Golf" advanced population
TS-065462 — The Need In the rubber industry, optimizing latex production while ensuring the sustainability of rubber-producing plants is essential. Rubber farmers face challenges such as fluctuating market demands, environmental pressures, and the need for consistent yield levels. To meet these challenges, the…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Cornish, Katrina; Fresnedo Ramirez, Jonathan; Wheeler, Brandon "Brandon"
  • Licensing Officer: Dahlman, Jason "Jay"

Antibiotic-free selection of plasmids for recombinant DNA technology applications
TS-065461 — The Need: In the field of modern biochemistry, the production of recombinant proteins in bacterial hosts like Escherichia coli is integral for both research and industrial applications. However, the traditional method of using antibiotics for selection in protein production is costly and contributes…
  • College: College of Arts & Sciences
  • Inventors: Gopalan, Venkat
  • Licensing Officer: Willson, Christopher

Targeted Nanobody Technology for Precise Antineoplastic Treatment
TS-065460 — The Need Cancer remains one of the most pressing medical challenges worldwide, necessitating novel therapeutic approaches to combat its proliferation. Despite advancements, targeted therapies are often limited by immune responses or cumbersome production processes. There's a growing demand for …
  • College: College of Arts & Sciences
  • Inventors: Magliery, Thomas; Palmieri, Dario; Ryan-Simkins, Michael
  • Licensing Officer: Willson, Christopher

Peptide-based inhibitor of host factor involved in HIV-1 replication
TS-065459 — The Need The emergence of HIV-1 infection continues to pose significant challenges in healthcare worldwide. Current treatment approaches primarily target viral components, leading to the development of drug resistance over time. There is a pressing need for innovative therapeutic strategies that di…
  • College: College of Arts & Sciences
  • Inventors: Musier-Forsyth, Karin; Tang, Yingke
  • Licensing Officer: Willson, Christopher

Precision RNA-PROTACs: Revolutionizing Therapeutic Targeting of Dysregulated Ribonucleoprotein Complexes
TS-065457 — The Need: In the realm of therapeutic development, there's a pressing need for precise targeting of dysregulated ribonucleoprotein (RNP) complexes to combat various diseases, particularly neurodegenerative disorders like ALS, Alzheimer’s, and Huntington’s diseases. Traditional metho…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"; Strong, Rebekah
  • Licensing Officer: Willson, Christopher

Revolutionizing RNA-Protein Interaction Mapping: Precision Proximity Labeling Technology
TS-065456 — The Need In modern biological research, there is a pressing demand for technologies that enable precise mapping of RNA-protein interactions within Ribonucleoprotein (RNP) complexes. Traditional methods often lack the capability to pinpoint these interactions at the level of secondary structure moti…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"
  • Licensing Officer: Willson, Christopher

Advancing RNA Detection with Innovative Peptide-Based Fluorescent Probes
TS-065455 — The Need: In modern biotechnology and biomedical research, there is an escalating demand for efficient tools that can accurately detect and analyze specific RNA sequences. The ability to precisely target and identify RNA molecules, particularly U-rich sequences, is crucial for various applications s…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; DeSantis, Christopher; Gopalan, Venkat; Liang, Yufeng; Mao, Jie; Marathe, Ila; Miao, Shiqin "Shiqin"
  • Licensing Officer: Willson, Christopher

Monoclonal Antibodies for Soybean Rust Diagnostic Assay
TS-065454 — The Need: As agriculture faces increasing challenges from plant pathogens, rapid and accurate detection methods are crucial to safeguarding crop yields and ensuring food security. Traditional methods of pathogen detection often suffer from delays in diagnosis, leading to significant crop damage and …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Dorrance, Anne; Luster, Douglas; McMahon, Michael; Miller, Sally
  • Licensing Officer: Dahlman, Jason "Jay"

MicroRNA profile predicts colon cancer prognosis
TS-065453 — The Need: Colon cancer remains one of the most prevalent and lethal forms of cancer worldwide. Timely and accurate diagnosis is critical for effective treatment and improved patient outcomes. Current diagnostic methods often lack the precision and sensitivity needed for early detection and prognosi…
  • College: College of Medicine (COM)
  • Inventors: Croce, Carlo
  • Licensing Officer: Dahlman, Jason "Jay"

Sacrificial Layer to Facilitate Welding of Thin Foils
TS-065430 — Cost-effective method to prevent damaged electrodes when welding thin foils.
Manufacturing of automotive lithium-ion batteries and battery packs is attracting growing attention with the driving demands of electric vehicles. During battery assembly, multi-layers of metal films, functioning as anodes, cathodes, or bus-bars are welded together. Achieving satisfying weld quali…
  • College: College of Engineering (COE)
  • Inventors: Liu, Xun; Kwon, Ho; Shah, Umair
  • Licensing Officer: Zinn, Ryan

Use of Cerium in Neutralizing Iron Impurity in Aluminum Alloys
TS-065429 — Iron is the main and most detrimental impurity in most industrial casting aluminum alloys. Iron content in aluminum alloys is limited, up to 0.1 weight% in some alloys.
Iron is a major impurity element in primary and secondary (scrap) aluminum alloys. It is difficult to remove during melting and casting. Controlling the formation of Al-Fe-based intermetallics via alloying is key to leveraging the mechanical properties of aluminum alloy products. The current struc…
  • College: College of Engineering (COE)
  • Inventors: Luo, Alan; Cinkilic, Emre; Moodispaw, Michael
  • Licensing Officer: Zinn, Ryan

Streamlined Die Design Approach for Friction Stir Extrusion
TS-065428 — The Ohio State University researchers led by Dr. Rajiv Shivpuri have developed a die design approach for friction stir extrusion that optimizes metal flow to improve production efficiencies.
Friction stir extrusion (FSE) is a variation of friction stir processing that enables the hot extrusion of metal profiles from billet or other precursor material without preheating. This process saves significant thermal energy over conventional metal extrusion processes and can impart favorable …
  • College: College of Engineering (COE)
  • Inventors: Shivpuri, Rajiv
  • Licensing Officer: Zinn, Ryan

Self-filling Friction Stir Welding Processing
TS-065427 — The Ohio State University has developed a novel self-filling friction stir welding tool that eliminates keyhole defects caused by tool pin retraction.
Friction stir welding (FSW) and friction stir processing (FSP) are solid-state processes that utilize the heat generated from a rotating pin tool to soften the base metals for fusion and repair, respectively. However, keyhole defects are inevitably left after retracting the tool pin, which can ge…
  • College: College of Engineering (COE)
  • Inventors: Liu, Xun
  • Licensing Officer: Zinn, Ryan

Open Circuit Voltage Photodetector
TS-065426 — Photodetectors are devices that detect light and convert it into an electrical signal. They operate based on the photoelectric effect, in which photons (light particles) strike the semiconductor material, creating electron-hole pairs that lead to the flow of electrical current that can be measured.
Existing photodetectors are susceptible to various noise sources, such as thermal and electronic. The noise can degrade the signal-to-noise ratio and affect the accuracy of measurements, particularly in low-light conditions. This technology is an open-circuit voltage photodetector (OCVP) that…
  • College: College of Engineering (COE)
  • Inventors: Krishna, Sanjay; Fuller, Earl; Kazemi, Alireza; Khalil, Waleed; Ronningen, TJ; Smith, Dale "Shane"; Specht, Teressa; Tantawy, Ramy "Ramy"
  • Licensing Officer: Zinn, Ryan

Containment System for Heating and Off-Gassing
TS-065424 — Due to environmental concerns and the decreasing supply of fossil fuels, there is substantial demand for nuclear-based energy production. Nuclear energy now provides about 10% of the world's electricity from about 440 power reactors and is the second largest source of low-carbon power. In addition, over 50 smaller countries utilize nuclear energy in about 220 research-size reactors. These reactors are used to produce medical and industrial isotopes and several other purposes.
It is essential to meet the safeguard requirements in liquid-fueled molten salt reactors, fuel salt transportation, and fuel cycle processes and to develop effective methods for measuring and monitoring the mass of molten fuel salt or coolant salt. However, due to the complex and dynamic nature o…
  • College: College of Engineering (COE)
  • Inventors: Van Zile, Matthew; Cao, Lei Raymond; Kauffman, Andrew
  • Licensing Officer: Zinn, Ryan

Fluid Active Flow Control Enabled Variable Turbine Vane
TS-065423 — Turbine aircraft engines (jet engines) are a type of propulsion system commonly used in aviation. These engines operate on jet propulsion, where air is drawn into the engine, mixed with fuel, ignited, and then expelled at high speed to generate thrust. Jet engines are used in commercial and military aircraft, as well as helicopters.
While turbine aircraft engines offer higher efficiency and performance than their counterparts, there is still a need to improve efficiency and reduce fuel consumption and greenhouse gases. It’s estimated that jet engines account for over 2.5% of all CO2 emissions, and there are substantial …
  • College: College of Engineering (COE)
  • Inventors: Spens, Alexander; Bons, Jeffrey
  • Licensing Officer: Zinn, Ryan

Highly Efficient Light Olefin Selectivity & Production Process
TS-065422 — Light olefins, such as ethylene and propylene, are essential building blocks in the petrochemical industry and have a wide range of uses in various applications. The most common uses for olefins include polymers, chemical intermediates, solvents, rubber, and nanomaterials, among others.
Although Light olefins are used globally in many products, the catalytic processes to produce them are energy intensive with a large carbon footprint and the production of greenhouse gases and water pollution. As a result, substantial efforts are being made in the industry to develop more sustain…
  • College: College of Engineering (COE)
  • Inventors: Ozkan, Umit; Gunduz, Seval; Kim, Jaesung
  • Licensing Officer: Zinn, Ryan

Halbach Cladding Magnets for Friction Reduction in Magnetic Gears
TS-065418 — Traditional mechanical gears rely on physical teeth engagement to transfer motion and torque while magnetic gears use the repulsive or attractive forces between magnets to achieve the same goal. Magnetic gears have several advantages: low noise and vibration, reduced maintenance, and inherent overload protection. Magnetic gears are used in applications that require variable speed control and precise torque transmission, such as robotics, aircraft, and automation.
Although magnetic gears provide several advantages to their traditional mechanical counterparts, they suffer from torque transmission inefficiency due to end-effect loss, which occurs when the magnetic flux leaks axially into the surrounding air and fails to couple between the rotors. As industri…
  • College: College of Engineering (COE)
  • Inventors: Dapino, Marcelo; Losey, Bradley "Brad"; Nas, Ismail
  • Licensing Officer: Zinn, Ryan

Unlocking Quantum Communication: Empowering Entangled Photon Pairs with Temperature-Insensitive Technology
TS-065416 — The Need: In the rapidly advancing realm of quantum information science, there's an escalating demand for reliable sources of entangled photon pairs. These photon pairs serve as fundamental building blocks for various quantum communication technologies. Presently, maintaining these sources neces…
  • College: College of Arts & Sciences
  • Inventors: Gauthier, Daniel
  • Licensing Officer: Willson, Christopher

Quantum Leap: Revolutionizing Computing and Sensing with Modular Zero-Dimensional Tunnel Junction Devices
TS-065414 — The Need: Innovations in the field of quantum technology are paramount to addressing the escalating demand for advanced computational capabilities and sensitive sensor applications. As traditional computing methodologies reach their limits, there arises an urgent commercial need for breakthroughs i…
  • College: College of Arts & Sciences
  • Inventors: Johnston-Halperin, Ezekiel; Gupta, Jay; Hamilton, Morgan; Kavand, Marzieh; Koll, Will; Perez-Hoyos, Ethel; Phillips, Zoe
  • Licensing Officer: Willson, Christopher

Secure Your Digital Fortress: Revolutionizing Cybersecurity with Next-Gen PUF Technology
TS-065412 — The Need: In contemporary cybersecurity landscapes, the conventional methods of employing Physically Unclonable Functions (PUFs) necessitate maintaining a secure challenge-response database. However, this practice poses significant security risks as access to this database could lead to the comprom…
  • College: College of Arts & Sciences
  • Inventors: Gauthier, Daniel
  • Licensing Officer: Willson, Christopher

Monolithically Integrated Tunnel Junction-Based GaN Light Emitting Transistors
TS-065398 — Emissive display technologies (e.g., OLEDs) are display technologies that emit light directly to produce images. Unlike reflective displays, which rely on external light sources, emissive displays generate light, resulting in vibrant and high-contrast visuals. These next-generation displays are used in several applications, including mobile devices, AV/VR headsets, and wearable devices.
Although emissive displays are integrated into many electronic devices, they face some challenges. One of the primary issues is the integration of LEDs and electronic drivers when scaling into mesa dimensions. The mesa is a crucial parameter in display manufacturing as it determines the size of th…
  • College: College of Engineering (COE)
  • Inventors: Rajan, Siddharth; Jamal-Eddine, Zane; Joishi, Chandan "Chandan"; Rahman, Sheikh Ifatur
  • Licensing Officer: Zinn, Ryan

Enhancing Antibody Therapies Using a NOD2 Agonist
TS-065320 — Stimulating monocytes with a NOD2 agonist increases effectiveness of monoclonal antibody therapy.
An estimated 20,160 new cases of chronic lymphocytic leukemia (CLL) and 4,410 deaths were expected in 2022. Current therapies for CLL include the administration of a monoclonal antibody, such as rituximab, an anti-CD20 antibody, to promote clearance of malignant B cells. The Need Current therapies…
  • College: College of Medicine (COM)
  • Inventors: Tridandapani, Susheela; Butchar, Jonathan; Mehta, Payal; Merchand Reyes, Giovanna; Santhanam, Ramasamy
  • Licensing Officer: Schultz, Teri

Ultra Sheer Technology (UST): Revolutionizing Protein Blending for Superior Nutrition and Taste
TS-065233 — The Need: The food industry grapples with meeting escalating consumer demands for health-centric, eco-friendly, and economically viable protein-based diets. Despite the surge in popularity of plant-based milk products, consumer reluctance persists due to lackluster flavors and compromised taste. Add…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Balasubramaniam, V M "Bala"; Janahar, Jerish Joyner; Jimenez-Flores, Rafael
  • Licensing Officer: Dahlman, Jason "Jay"

Novel Extracellular Vesicles Loaded with Anti-Inflammatory Agents
TS-065154 — Revolutionary treatment for ARDS using novel extracellular vesicles loaded with Anti-Inflammatory Agents.
The Need Acute Respiratory Distress Syndrome (ARDS) remains a significant healthcare challenge with high mortality rates and long-term morbidity. Despite advancements in supportive care, there’s an urgent need for pharmacologic treatments targeting the molecular mechanisms driving ARDS pathog…
  • College: College of Medicine (COM)
  • Inventors: Karpurapu, Manjula; Christman, John; Parinandi, Narasimham
  • Licensing Officer: Schultz, Teri

Bio-Matched Horn: A Novel 1-9 GHz On-Body Antenna for Low-Loss Biomedical Telemetry with Implants
TS-065135 — The use of wearable health devices has more than tripled in recent years due to the ability of these products to collect health data to detect potential health events (e.g., heart attacks), manage chronic diseases, and track physical activity. Wearable technologies have been shown to decrease the nu…
  • College: College of Engineering (COE)
  • Inventors: Blauert, John; Kiourti, Asimina
  • Licensing Officer: Randhawa, Davinder

Environmental Damage Model for Predicting Mechanism Transition under Time-Dependent Crack Growth Conditions.
TS-065131
  • College: College of Engineering (COE)
  • Inventors: Viswanathan, Gopal; Mills, Michael; Mills, David
  • Licensing Officer: Randhawa, Davinder

Combination B Cell Epitope Vaccines for Cancer Treatment
TS-064843 — , T2022-244, T2020-109 : Cancer vaccines targeting a combination of B Cell epitopes to improve patient outcomes.
The Need Despite the clinical success of checkpoint receptor blockade in various cancer subtypes, many patients develop resistance, presenting a pressing need for novel approaches. Current inhibitors, like PD-1/PD-L1 and HER-2 exhibit limited efficacy and significant toxicities, underscoring the d…
  • College: College of Medicine (COM)
  • Inventors: Kaumaya, Pravin
  • Licensing Officer: Schultz, Teri

Unveiling Unreported Pain: A Systematic Approach for Enhanced Patient Care
TS-064835 — The Need In healthcare, accurately assessing and managing pain is paramount for patient well-being and treatment efficacy. However, conventional methods of pain assessment rely heavily on verbal communication from patients, which poses challenges for individuals unable to express their pain verball…
  • College: College of Nursing
  • Inventors: Monroe, Todd
  • Licensing Officer: Wilburn, Adri

IR Precision: Revolutionizing Colorectal Cancer Metastasis Diagnosis with the CCML Library
TS-064834 — The Need: Colorectal cancer remains a significant global health challenge, particularly when it metastasizes to the liver. Accurate and rapid diagnosis of metastatic liver lesions is crucial for effective treatment planning and patient outcomes. Traditional diagnostic methods often lack the specific…
  • College: College of Arts & Sciences
  • Inventors: Coe, James; Allen, Heather; Bradley, Rebecca; Hitchcock, Charles; Martin, Edward
  • Licensing Officer: Willson, Christopher

Buckeye Paws: Transforming Mental Health with Innovative Therapy Dog Intervention
TS-064833 — The Need: In today's high-stress environments, maintaining mental and emotional well-being is paramount for employees and students alike. Buckeye Paws addresses this crucial need by offering a unique therapy dog intervention designed to promote comfort, happiness, and resilience within The Ohio …
  • College: College of Medicine (COM)
  • Inventors: Steinberg, Beth; Justice, Mary; Mitchell, Aimee
  • Licensing Officer: Wilburn, Adri

Machine Learning Aided Concentration Prediction of Organic Compounds in the Sea Surface Microlayer by Vibrational Spectroscopic Methods
TS-064832 — The Need: The chemical composition of the sea surface microlayer (SSML) plays a crucial role in various environmental processes, impacting atmospheric chemistry and oceanic dynamics. However, traditional analytical methods struggle to efficiently characterize the complex and variable composition of …
  • College: College of Arts & Sciences
  • Inventors: Allen, Heather; Enders, Abigail; North, Nicole
  • Licensing Officer: Willson, Christopher

Semi-automatic extraction of georeferenced building data from historic Sanborn Fire Atlas maps
TS-064831 — The Need: Urban historians, city planners, and preservationists require efficient tools to extract building-level information from historic Sanborn Fire Insurance maps, essential for understanding urban development over time. However, manual extraction is time-consuming and impractical due to the sh…
  • College: College of Arts & Sciences
  • Inventors: Miller, Harvey; Li, Jialin; Lin, Yue; Logan, Gerika; Porr, Adam; Xiao, Ningchuan
  • Licensing Officer: Willson, Christopher

Remembrance & Renewal- Empowering Healthcare Teams with Relationship-Based Care
TS-064830 — The Need: In today's healthcare landscape, the management of oncology patients has evolved to resemble that of chronic illness, necessitating a shift towards holistic care models like Relationship-Based Care (RBC). As patients with chronic diseases, including cancer, live longer, healthcare prof…
  • College: OSU Wexner Medical Center
  • Inventors: Rettig, Amy "Amy"; Arpin, Rachel; Bohley, Kathy; Lambrecht-Stock, Emily
  • Licensing Officer: Wilburn, Adri

Earth-Abundant Transition Metal Catalysts for Sustainable Hydrofunctionalization Reactions
TS-064828 — The Need: Transition metal-catalyzed hydroelementation reactions address a critical demand in various industries by facilitating the addition of H-E (E = H, Si, B) across C-C double bonds. These reactions are vital in the chemical sector, particularly in the petrochemical, pharmaceutical, agrochemic…
  • College: College of Arts & Sciences
  • Inventors: Thomas, Christine; Fitzsimmons, Matthew
  • Licensing Officer: Willson, Christopher

Metalloproteins as a tunable scaffold for constructing quantum bits and dits for use in quantum information storage and processing
TS-064827 — The Need: As the second quantum revolution progresses, the demand for robust quantum materials intensifies, particularly in the realm of quantum computation and information processing. Addressing the challenges of coherence and stability in qubits is crucial for advancing quantum technology towards …
  • College: College of Arts & Sciences
  • Inventors: Shafaat, Hannah "Hannah"; Johnston-Halperin, Ezekiel; Teptarakulkarn, Pathorn
  • Licensing Officer: Willson, Christopher

Methods to improve the jitter and time walk of integrated constant fraction discriminators
TS-064826 — The Need Accurate measurements of energy and time-of-arrival of photons, particles, or ionizing radiation are crucial for identifying individual particles and enhancing spatial and temporal resolution in various systems. Technologies such as Light Detection and Ranging (LiDAR), positron emission to…
  • College: College of Arts & Sciences
  • Inventors: Kagan, Harris; Abusareya, Mo'men; Khalil, Waleed; Smith, Dale "Shane"
  • Licensing Officer: Willson, Christopher

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