TS-067045 — The Need Wireless implants with integrated antennas are highly desirable for diagnostic, therapeutic, and monitoring applications due to their ability to communicate directly with external devices. However, the need for major surgical incisions to implant these devices poses significant risks, incl…

TS-066963 — The Need Exposure to mold in homes costs billions of dollars every year. Exposure is particularly harmful to the 8% of the United States population that suffers from asthma; a leading cause of disability in children. Currently, odor, visible mold growth, and dampness are the best indicators of mold…

TS-066962 — The Need Viral disease surveillance (e.g. influenza, SARS-CoV-2) in high-risk settings faces several challenges, such as asymptomatic carriers, incomplete reporting, resource limitations, and delayed diagnosis of traditional swab test methods. These challenges could allow a virus to silently spread…

TS-066960 — The Need Indoor air can be polluted by various sources, including building materials, furniture, cleaning products, and even people. Exposure to these resulting contaminants and allergens can lead to a variety of health problems, such as respiratory irritation, allergies, and even cancer. It is cur…

TS-066957 — The Need Colorimetric tests and remote image analysis are used in a wide range of industrial and medical applications. Digital image-based measurements made with smartphones are a promising platform to quantify colors at low cost, but suffer from inconsistency and errors caused by lens quality, sen…

TS-066926 — This Ohio State University software innovation offers groundbreaking analytical speed and automation of Single-Molecule Localization Microscopy (SMLM) as well as analysis of 3D data and images extending beyond the field of microscopy. Our technology offers real-time spatial analysis in continuous and discrete space, enabling unprecedented speed and efficiency in data processing that translates into faster decision-making, high-throughput screening capabilities, and broad applicability beyond traditional microscopy.

TS-066912 — Targeted humanized mAbs and ADCs for cancer treatment

TS-066793 — The Need In agriculture, the accurate measurement of gasses such as nitrous oxide (N2O) and nitrogen oxides (NOx) is crucial for optimizing fertilizer use, minimizing greenhouse gas emissions, and reducing air pollution. Current monitoring technologies are often expensive, complex, and not suitable…

TS-066773 — The Need Cardiomyopathy, a disease of the heart muscle, poses significant public health challenges due to its diverse causes, symptoms, and potential complications, including heart failure and arrhythmias. With cardiomyopathy often induced by drugs, such as anthracyclines used in chemotherapy, ther…

TS-066772 — The Need Biofilms, particularly dental plaque-biofilms, are communities of microorganisms encased in a slimy extracellular polymeric substance (EPS) that adhere to surfaces or neighboring microorganisms. These biofilms are responsible for various infectious diseases, including oral diseases such as…

TS-066771 — Endothelial injury is a significant pathological mechanism underlying various neurological disorders, including neurodegenerative, neuroinflammatory, and cerebrovascular diseases. Current clinical and research settings lack reliable biomarkers to detect or measure endothelial injury in the human C…

TS-066770 — The Need In the realm of human and mammalian health, delivering biologically active components that are sensitive to moisture or other environmental factors has posed a significant challenge. Traditional methods, such as encapsulation or use of desiccants, often fall short in ensuring stability and…

TS-066752 — In today's fast-paced commercial and scientific environments, there is an increasing demand for precise and efficient analytical techniques capable of handling complex mixtures with diverse physicochemical properties. Existing ionization techniques like Electrospray Ionization (ESI) and Atmosp…

TS-066751 — In the rapidly evolving field of biotechnology and pharmaceuticals, there is a critical need for efficient delivery mechanisms to transport therapeutic agents directly into cells. Traditional methods face challenges with membrane impermeability and degradation of therapeutic compounds, limiting th…

TS-066750 — The ongoing COVID-19 pandemic, caused by the SARS-CoV-2 virus, has significantly impacted global health and economies. Despite vaccine efforts, issues such as vaccine hesitancy, delays in distribution, and emerging variants have highlighted the need for effective therapeutic interventions. These i…

TS-066252 — Rotating Fuel Core with Fuel Strip(s) ("ROFFUS") is an innovative modular nuclear reactor core designed to provide reliable and scalable power for advanced space missions.

TS-066250 — A cutting-edge sensor system featuring p-n junctions in MOS materials for accurate detection and identification of gases.

TS-066249 — A novel sensor leveraging WO3 and Cr2O3 for selective NO detection in harsh environments and breath analysis with high sensitivity at ppb levels.

TS-066246 — Our innovative CO sensor utilizes hydrated ruthenium oxide to detect carbon monoxide within a gas mixture with high sensitivity and selectivity at temperatures ranging from 25°C to 300°C.

TS-066239 — There is a critical need for advanced high-temperature NOx sensors to accurately monitor and control combustion environments, ensuring compliance with government regulations and mitigating the harmful effects of NOx on ecosystems and public health. Our new NOx sensor is designed to detect total…

TS-066235 — Oxygen sensors are crucial for monitoring oxygen levels in combustion and industrial processes, but current sensors require complex plumbing for reference gas, limiting their placement and operational temperature range. There is a pressing need for a robust, high-temperature oxygen sensor that is …

TS-066234 — In the realm of rotating machinery and structural engineering, the need to manage and mitigate vibrations is paramount. Excessive vibrations can lead to material fatigue, operational inefficiency, and catastrophic failures. Industries require a sophisticated, accurate, and versatile tool to design…

TS-066233 — Protein analysis is foundational to understanding human physiology and is helpful for basic research, diagnosis, guiding treatment, and monitoring of human disease. There are several widely used platforms for evaluating protein function. The primary tools used in protein analysis on cells and tissues include antibody/aptamer, fluorescent detection systems, and mass spectrometry.

TS-066100 — Research tool to transfect cells ex vivo using electroporation through electrospun core-shell fibers for research applications

TS-066063 — Our cybersecurity vulnerability maintenance system stands as a pillar of modern security strategy, transforming reactive security measures into a preemptive defense mechanism. This integration of technology and economics ensures that your most critical assets are protected efficiently and effectively, making it an invaluable tool for any organization serious about security.

TS-066058 — By adopting our AI-driven solution, engineering teams can achieve more in less time, push the boundaries of innovation, and significantly cut down costs, all while maintaining or increasing the reliability and accuracy of their structural and material analysis. This is not just an evolution in FEM technology—it's a revolution.

TS-066056 — The Need The advancement of lithium-ion battery technology relies heavily on increasing energy density, yet practical usage of silicon (Si) anodes faces challenges due to parasitic side reactions and active lithium consumption. Controlling lithium amounts precisely while achieving uniform distribut…

TS-066052 — Novel T-cells expressing the IL-2a receptor to enhance cancer cell targeting.

TS-066051 — Novel antibodies targeting IL-2 with the ability to inhibit IL-2 signaling through IL-2 Rαβg to a greater extent than through IL-2 Rβg.

TS-066037 — The Need In the realm of materials science and energy storage, there's a growing demand for innovative anode synthesis methods that yield materials with improved mechanical and electrochemical properties. Traditional synthesis techniques often fall short in achieving the desired performance met…

TS-066016 — The Need Redox flow batteries (RFBs) offer a promising solution for storing intermittent renewable energy in the electrical grid. However, their reliance on finite and unsustainable transition metals, such as vanadium, poses significant sustainability challenges. The rising costs and environmental …

TS-066015 — The Need Over the past two decades, the advancement of metal-O2 batteries has been hindered by issues of instability, reversibility, and poor energy efficiency, primarily due to the instability of superoxide in the presence of Li+ and Na+ ions. Existing solutions such as Li-O2 and Na-O2 batteries h…

TS-065913 — Gene therapy strategies for treating peripheral neuropathy.

TS-065892 — The Need The microscopic worm C. elegans is a model animal studied in more than 1500 biological and medical research laboratories worldwide due to its genetic manipulability and optical transparency. In C. elegans research, the manual process of picking worms between plates presents a significant …

TS-065863 — The Need: Contaminated vacant lots pose significant environmental and health risks in urban areas, especially in lower-income neighborhoods. Anthropogenic activities such as mining, industrial processes, and combustion lead to the accumulation of organic pollutants and heavy metals like lead, arseni…

TS-065862 — The Need In the landscape of cancer treatment, the emergence of immunotherapy has shown remarkable promise. However, its efficacy is not universal across all cancer types, and resistance development poses a significant challenge. Hyperprogression, characterized by accelerated tumor growth, further …

TS-065860 — The Need: Cancer remains one of the most pressing medical challenges of our time, demanding innovative solutions to enhance treatment efficacy while minimizing systemic toxicity. Conventional chemotherapy agents often suffer from poor solubility, instability, and indiscriminate cytotoxicity, necessi…

TS-065859 — FIELD: Revolutionizing Canine Lung Cancer Treatment The Need: Lung cancer in canines poses significant clinical challenges, mirroring the complexities of human lung cancer in non-smokers. With limited standard treatments beyond surgery, there's an urgent demand for advanced methods to assess, c…

TS-065858 — The Need: In the modern agricultural landscape, tomato crops face significant threats from bacterial spot, Verticillium, and Fusarium, leading to substantial yield losses and economic strain for growers. Addressing these challenges is crucial to ensure a sustainable and profitable tomato industry. …

TS-065857 — The Need: In today's agricultural landscape, optimizing crop yield and quality is paramount to meet the growing demand for food. Farmers face the challenge of selecting crop varieties that offer resilience to various environmental stressors while maintaining high productivity levels. Additionall…