IR Precision: Revolutionizing Colorectal Cancer Metastasis Diagnosis with the CCML Library
TS-064834 — The Need: Colorectal cancer remains a significant global health challenge, particularly when it metastasizes to the liver. Accurate and rapid diagnosis of metastatic liver lesions is crucial for effective treatment planning and patient outcomes. Traditional diagnostic methods often lack the specific…
- College: College of Arts & Sciences
- Inventors: Coe, James; Allen, Heather; Bradley, Rebecca; Hitchcock, Charles; Martin, Edward
- Licensing Officer: Dahlman, Jason "Jay"
High-K Dielectric barriers to suppress internal photoemission photocurrents
TS-063471 —
In an increasingly digital world, the demand for efficient and reliable photodetectors is paramount. These devices are critical for a variety of applications, from medical imaging to defense systems. However, traditional photodetectors often struggle with low UV-visible rejection, limiting their e…
- College: College of Engineering (COE)
- Inventors: Rajan, Siddharth; McGlone, Joseph "Joe"; Wriedt, Nathan
- Licensing Officer: Zinn, Ryan
A Regularized Conditional GAN for Posterior Sampling in Inverse Problems
TS-063238 — A novel regularization technique applicable for medical imaging applications that leverages conditional generative adversarial networks (cGANs) to generate reconstructed images in significantly shorter timeframes.
The Need
Several techniques are used for image reconstruction in the medical aren…
- College: College of Engineering (COE)
- Inventors: Bendel, Matthew; Ahmad, Rizwan; Schniter, Philip
- Licensing Officer: Hampton, Andrew
Tracking Breast Tissue Tumor Cavity after Lumpectomy
TS-062715 — Radiopaque biodegradable polymer for the tracking of the breast tissue tumor cavity after lumpectomy and other radiation therapy applications
Approximately 40% of women diagnosed with breast cancer undergo a lumpectomy procedure. Approximately 170,000 lumpectomie are performed each yaer in the United States. Typically, this operation is followed by radiation therapy to ensure there are no remaining cancerous cells in the region. It is t…
- College: College of Engineering (COE)
- Inventors: Metzler, Sandra; Elisha, Deji; Evans, Izzy; Fedro, Joseph; Krakovsky, Mia; Sherry, Adam; Skoracki, Roman
- Licensing Officer: Zinn, Ryan
Methods and Apparatus to Improve MRI Efficiency
TS-062627 — Magnetic Resonance Imaging (“MRI”) is one of the most important modern medical imaging modalities. It has far less risk of side effects than most other imaging modalities. Generally, a high quality image requires high signal-to-noise ratio, high contrast between normal and pathological t…
- College: College of Arts & Sciences
- Inventors: Wang, Jinghua
- Licensing Officer: Panic, Ana
Methods to measure biophysical attributes of the posterior eye
TS-062505 — The Need
Glaucoma and myopia are significant causes of vision loss worldwide, affecting millions of people and imposing a substantial socioeconomical burden. Effective vision care strategies are urgently needed to reduce blindness caused by these conditions and mitigate their associated risks. In v…
- College: College of Engineering (COE)
- Inventors: Liu, Jun; Kwok, Sunny
- Licensing Officer: Randhawa, Davinder
Methods for quantifying the biomechanical attributes of the cornea and the anterior sclera
TS-062497 — The Need:
The field of ophthalmology requires advanced diagnostic tools to effectively diagnose, prevent, and treat various eye conditions. While ultrasound imaging is well-known in fields like pregnancy check-ups and vascular imaging, its potential in ophthalmology remains largely untapped. There …
- College: College of Engineering (COE)
- Inventors: Liu, Jun; Kwok, Sunny
- Licensing Officer: Randhawa, Davinder
Optimizing Magnetic Resonance Imaging (MRI) protocols
TS-062328 — The Need
Medical imaging plays a crucial role in modern healthcare, aiding in the accurate diagnosis and treatment of various diseases. Magnetic Resonance Imaging (MRI) is a widely used non-invasive imaging modality that offers significant advantages over other techniques due to its lack of ionizin…
- College: College of Arts & Sciences
- Inventors: Wang, Jinghua; He, Lili; Lu, Zhong-Lin; Parikh, Nehal
- Licensing Officer: Dahlman, Jason "Jay"
X-Ray Assistive Device for Standardizing the Knee Templating Process
TS-054471 — Knee templating is used as part of the pre-operative planning for knee replacement to determine the best fit for an implant. The current assistive devices used to determine fit are unreliable and inaccurate for proper patient fit. A new device is suggested to overcome these limitations.
Over 600,000 knee replacements are performed per year. As part of the pre-operative planning for surgery, x-ray images are taken to determine the proper fit for the implant. Even with the use of a calibration ball, this knee templating procedure remains inaccurate and unreliable for a number of re…
- College: College of Engineering (COE)
- Inventors: Ruegsegger, Mark; Aery, Dylan; Browske, Kimberly; Cantrell, Kaleb "Kaleb"; Reilman, Zach; Thew, Maddie
- Licensing Officer: Bhatti, Hamid
DNA-cage erasable labels for fluorescence-based imaging
TS-043819 — Compositions and methods for analyzing multiple biomarkers without damaging tissue.
Histopathology is a cornerstone of tissue analysis used to diagnose many clinical conditions. Many of these diagnoses are based on identifying the presence of specific biomarkers, which can be indicated by colored labels. Currently, only 1-2 markers can be analyzed per slide, reducing accuracy and…
- College: College of Engineering (COE)
- Inventors: Winter, Jessica; Jergens, Elizabeth; Lee, Kil Ho "Kilho"
- Licensing Officer: Willson, Christopher
Folding Transducer Array for Compact and Deployable Wave-Energy Guiding System
TS-043186 — A novel acoustic/ultrasonic wave-energy guiding system that utilizes structural topology to enhance directional and spectral sensitivities instead of phase delay, offering exceptional versatility and adaptable performance.
Although acoustic beamforming systems that are based on phase delays can be used to enhance directional and spectral sensitivities, each source or receiver must be individually controlled by appropriate phase delays to guide the acoustic energy radiation/reception sensitivities. This results in a …
- College: College of Engineering (COE)
- Inventors: Harne, Ryan
- Licensing Officer: Zinn, Ryan
In Canopy Crop Health Sensing Technology
TS-036526 — A remote sensing imaging system that combines a suspended camera with sampling probes, combined with unique image processing features.
The Need
In modern agriculture, early detection and intervention are crucial to maximizing crop yield and minimizing losses. Traditional methods of crop health monitoring, relying on human scouts positioned at field borders, are limited and often lead to subjective decisions and delayed detection o…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Shearer, Scott; Klopfenstein, Andrew "Andrew"; See, David; Weigman, Christopher
- Licensing Officer: Dahlman, Jason "Jay"