# of Displayed Technologies: 27 / 27

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3D Object-based Segmentation-based Quantification of Spatial Protein Organization (OBS3D)
TS-066233 — Protein analysis is foundational to understanding human physiology and is helpful for basic research, diagnosis, guiding treatment, and monitoring of human disease. There are several widely used platforms for evaluating protein function. The primary tools used in protein analysis on cells and tissues include antibody/aptamer, fluorescent detection systems, and mass spectrometry.
Colocalization analysis is the current standard technique for assessing spatial association of co‐labeled proteins in cells using multicolor immunofluorescence images. However, these tools are limited because multiple antigens nearby exhibit overlapping staining, which leads to inaccurate analys…
  • College: College of Engineering (COE)
  • Inventors: Veeraraghavan, Rengasayee
  • Licensing Officer: Zinn, Ryan

Streamline Your Building Design Workflow with AutoCAD to Revit Conversion Technology
TS-065818 — The Need In the architecture, engineering, and construction (AEC) industry, the need for seamless and efficient conversion of AutoCAD drawings to Revit models is paramount. As projects grow in complexity and scale, the ability to transition seamlessly between these platforms becomes essential for m…
  • College: Senior VP Admin & Planning
  • Inventors: Porostosky, Joseph; Palmer, Tracy; Pifher, David
  • Licensing Officer: Dahlman, Jason "Jay"

Quantum Information Protection Solution: Revolutionizing Quantum Computing
TS-064823 — The Need: In the burgeoning field of quantum computing, the primary commercial challenge lies in maintaining the integrity of quantum bits (qubits) amidst environmental interactions. Traditional methods struggle to prevent decoherence, hindering the scalability and reliability of quantum systems. Ad…
  • College: College of Arts & Sciences
  • Inventors: Trivedi, Nandini; Szabo, Joseph
  • Licensing Officer: Dahlman, Jason "Jay"

Systems and Methods of Reminding Drivers of the Stalking Vehicles on the Road
TS-063308 — In today’s world, privacy and safety are paramount. Being followed by other vehicles during driving can be unnerving and potentially dangerous, leading to privacy leakage and even significant traffic accidents. There is a pressing need for a solution that can detect abnormal following vehicl…
  • College: College of Engineering (COE)
  • Inventors: Sun, Wei; Srinivasan, Kannan
  • Licensing Officer: Randhawa, Davinder

A Regularized Conditional GAN for Posterior Sampling in Inverse Problems
TS-063238 — A novel regularization technique applicable for medical imaging applications that leverages conditional generative adversarial networks (cGANs) to generate reconstructed images in significantly shorter timeframes. The Need Several techniques are used for image reconstruction in the medical aren…
  • College: College of Engineering (COE)
  • Inventors: Bendel, Matthew; Ahmad, Rizwan; Schniter, Philip
  • Licensing Officer: Hampton, Andrew

Network-based Approach for Accurate Brain Modeling
TS-062628 — More than a billion people worldwide suffer from some neurological disorders, such as Alzheimer's, Parkinson's, multiple sclerosis, epilepsy, stroke, autism, addiction, and many others. These conditions result in more than 7 million deaths, with associated costs exceeding $1.5 trillion annua…
  • College: College of Arts & Sciences
  • Inventors: Cranmer, Skyler; Bhamidi, Shankar; Denny, Mathew; Desmarais, Bruce; Lu, Zhong-Lin; Stillman, Paul; Wilson, James
  • Licensing Officer: Dahlman, Jason "Jay"

NMR Spectra Analysis of NMR Software
TS-062576 — Nuclear Magnetic Resonance (NMR) allows the molecular structure of a material to be analyzed by observing and measuring the interaction of nuclear spins via a powerful magnetic field. NMR can be used to determine molecular conformation in solution and physical properties at the molecular level such …
  • College: Enterprise for Research, Innovation and Knowledge (ERIK)
  • Inventors: Li, Da-Wei; Bruschweiler, Rafael
  • Licensing Officer: Dahlman, Jason "Jay"

NMR Spectra Analysis of NMR Software
TS-062574 — Nuclear Magnetic Resonance (NMR) allows the molecular structure of a material to be analyzed by observing and measuring the interaction of nuclear spins via a powerful magnetic field. NMR can be used to determine molecular conformation in solution and physical properties at the molecular level such …
  • College: College of Arts & Sciences
  • Inventors: Li, Dawei "Dawei"; Bruschweiler, Rafael
  • Licensing Officer: Dahlman, Jason "Jay"

A novel computational procedure for accelerated, calibrationless magnetic resonance image reconstruction (Free-breathing Accelerated MRI Portfolio)
TS-062487 — Magnetic Resonance Imaging (MRI) is a versatile noninvasive imaging tool that is routinely used to evaluate many diseases and conditions. MRI offers exquisite soft tissue contrast and high spatial resolution to enable comprehensive structural and functional assessment of internal organs. Recent innovations in data acquisition and processing can expand the clinical applications of MRI.
The Need A major limitation of MRI is slow data acquisition, which can compromise patient comfort, drive up costs, and increase susceptibility to motion. The clinical adoption of volumetric imaging for musculoskeletal and neuro applications, the growing demand for free-breathing real-time imaging …
  • College: College of Engineering (COE)
  • Inventors: Zhao, Shen; Ahmad, Rizwan; Potter, Lee
  • Licensing Officer: Randhawa, Davinder

Golden-shift Ordered Cartesian sampling (GOC) for Dynamic MRI (Free-breathing Accelerated MRI (Portfolio)
TS-062486 — Magnetic Resonance Imaging (MRI) is a versatile noninvasive imaging tool that is routinely used to evaluate many diseases and conditions. MRI offers exquisite soft tissue contrast and high spatial resolution to enable comprehensive structural and functional assessment of internal organs. Recent innovations in data acquisition and processing can expand the clinical applications of MRI.
The Need A major limitation of MRI is slow data acquisition, which can compromise patient comfort, drive up costs, and increase susceptibility to motion. The clinical adoption of volumetric imaging for musculoskeletal and neuro applications, the growing demand for free-breathing real-time imaging …
  • College: College of Engineering (COE)
  • Inventors: Ahmad, Rizwan; Jin, Ning; Liu, Yingmin; Simonetti, Orlando
  • Licensing Officer: Randhawa, Davinder

Mass Casualty Incident Virtual Reality Training Simulation
TS-062343 — The Need: In the face of mass casualty incidents, first responders play a critical role in saving lives and minimizing the impact of disasters. However, traditional training methods using mock patients or mannequin simulators for mass casualty triage are costly, challenging to replicate, and requir…
  • College: College of Arts & Sciences
  • Inventors: Price, Alan; Berezina-Blackburn, Vitalya; Oliszewski, Alex; Swearingen, Scott; Winegardner, Zachary
  • Licensing Officer: Willson, Christopher

Virtual Reality Dementia Simulation: Fostering Empathy and Understanding
TS-062339 — The Need: Dementia poses one of the most significant challenges for older populations and their families. Understanding the experiences and struggles of those living with dementia is crucial for both families and potential caregivers. Existing simulations primarily focus on sensory deterioration, bu…
  • College: College of Arts & Sciences
  • Inventors: Berezina-Blackburn, Vitalya; Cleaver, Dreama; Oliszewski, Alex; Udakandage, Lakshika
  • Licensing Officer: Willson, Christopher

Visual Function Mapping Technology: Enhancing Vision Care and Diagnostics
TS-062335 — The Need: In the field of ophthalmology and vision care, there is a critical need for accurate and comprehensive measurements of visual function over the entire visual field. Conditions such as glaucoma, age-related macular degeneration (AMD), diabetes, stroke, pituitary disease, brain tumors, and n…
  • College: College of Arts & Sciences
  • Inventors: Lu, Zhong-Lin; Lesmes, Luis; Xu, Pengjing "PJ"; Yu, Deyue
  • Licensing Officer: Dahlman, Jason "Jay"

MRI Transmit Field Estimation in K-space Domain
TS-062329 — The Need: Medical imaging plays a crucial role in diagnosing various diseases, and Magnetic Resonance Imaging (MRI) has emerged as one of the most important imaging modalities due to its safety and effectiveness. Unlike other imaging methods that use ionizing radiation, MRI poses far fewer risks to …
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua; Ding, Yu
  • Licensing Officer: Panic, Ana

Optimization of 3D Magnetization-Prepared Rapid Gradient-Echo (MPRAGE) Sequence in Magnetic Resonance Imaging (MRI)
TS-062310 — The Need Medical imaging plays a crucial role in diagnosing various diseases and conditions. Magnetic Resonance Imaging (MRI) has emerged as one of the most significant and preferred medical imaging modalities due to its non-invasive nature and low risk of side effects compared to other imaging met…
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua; Lu, Zhong-Lin
  • Licensing Officer: Dahlman, Jason "Jay"

Correcting Signal Inhomogeneity in Magnetic Resonance Imaging (MRI)
TS-062309 — The Need: Signal intensity inhomogeneity in Magnetic Resonance (MR) imaging presents a significant challenge, leading to degradation in image quality, obstructed diagnoses, reduced accuracy in quantitative analyses, and increased inter-scanner variability. The lack of effective inhomogeneity correct…
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua; Constable, Robert; Lu, Zhong-Lin
  • Licensing Officer: Dahlman, Jason "Jay"

Accurate Characterization of Signal Coil Receive Sensitivity in Magnetic Resonance Imaging (MRI)
TS-062307 — The Need: Accurate characterization of receiver sensitivity is crucial for magnetic resonance imaging (MRI) techniques, particularly fast MRI using multi-channel coils. Different coils sample various parts of the k-space simultaneously during parallel MRI, and the final image's accuracy depends …
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua; Lu, Zhong-Lin
  • Licensing Officer: Dahlman, Jason "Jay"

Dynamic Removal of Clutter to Improve Situational Awareness in Traffic Management Systems
TS-054551 — Algorithm/software that dynamically classifies and removes clutter in systems such as the traffic management systems of Unmanned Aircraft Systems Traffic Management (UTM) and Urban Air Mobility (UAM).
The Unmanned Aerial Vehicle (UAV) market is predicted to be worth $56.18 billion by 2027. The global commercial UAV market size alone was valued at $13.44 billion in 2020, with a recorded demand of over 689,000 units. With a wide range of applications, the UAV market is expected to grow at 19.9% C…
  • College: College of Engineering (COE)
  • Inventors: Singhal, Achal
  • Licensing Officer: Zinn, Ryan

3D Clinical Image-based Pre-surgical planning Tool
TS-053757 — Modernity has brought with it increased complexity in many areas of our lives, an important one being the healthcare industry. Surgical procedures require increased precision while employing intricate methods. With approximately 20 million surgeries performed each year in the United States alone, …
  • College: College of Medicine (COM)
  • Inventors: Powell, Kimerly; Adunka, Oliver; Hittle, Bradley; Keith, Jason; Kerwin, Thomas "Thomas"; Stredney, Donald; Wiet, Gregory
  • Licensing Officer: Randhawa, Davinder

Process Monitoring of Internal Temperature Distribution of Powder Bed Fusion Parts
TS-047605 — An ensemble kamlan filter (EnKF) state observer algorithm and process monitoring method for more quickly and accurately estimating the internal temperature gradient of Powder Bed Fusion parts for enhanced process monitoring and control.
Powder Bed Fusion (PBF) is a subset of additive manufacturing processes that performs a layer-by-layer fabrication of metal components by selectively melting metal powder disbursed over the earlier layer. PBF processes encompass methods such as selective laser sintering (SLS), direct metal laser s…
  • College: College of Engineering (COE)
  • Inventors: Wood, Nathaniel; Hoelzle, David
  • Licensing Officer: Zinn, Ryan

Virtual image generation of immunohistochemical stained tissue sections using an artificial neural network
TS-039781 — Realistic immunohistochemical stained tissue section databases for training, certification, and machine standards.
Immunohistochemistry (IHC) is used to determine antigen distribution in a tissue and is widely used for diagnosis of cancers and other diseases. Diagnostic and research laboratories in the United States use locally devised IHC tissue slide preparation and scanning protocols to check scanner perfor…
  • College: College of Medicine (COM)
  • Inventors: Gurcan, Metin; Lozanski, Gerard; Senaras, Caglar
  • Licensing Officer: Hampton, Andrew

Automated Detection of Tumor Budding in Colorectal Cancer
TS-039267 — A non-invasive and automated tumor budding image analysis system for colorectal cancer. This program can detect tumor buds in traditional H&E stained sections without the need for manual assessment.
Colorectal cancer is the third most commonly diagnosed cancer in the United States. With a survival rate of less than 65%, early detection and treatment are key factors in survival. Tumor budding, associated with higher tumor stage, lymph node metastasis, and decreased disease-free survival, has e…
  • College: College of Medicine (COM)
  • Inventors: Gurcan, Metin; Ahmad Fauzi, Mohammad Faizal; Chen, Wei "Wei"; Frankel, Wendy
  • Licensing Officer: Hampton, Andrew

Design and apparatus for quantification of the mapping of the sensory areas of the brain
TS-039164 — A new tool that can quantify the sensory maps of the human brain. The tool can be used to quantify plasticity and pathology in the sensory areas of the human brain that are associated with normal and abnormal development, aging, and diseases in sensory systems. The first application of the tool, on retinotopic maps of the visual cortex, has generated excellent results.
By analyzing the stimulus­-referred fMRI responses in each voxel of an MR image, retinotopic mapping of human visual cortex can generate cortical maps of the visual space. These maps elucidate the spatial organization of the neuronal responses to visual images. Although numerous studies have b…
  • College: College of Arts & Sciences
  • Inventors: Wang, Yalin; Lu, Zhong-Lin
  • Licensing Officer: Dahlman, Jason "Jay"

At-Home Digital Platform for Scoring Skin Disease
TS-038429 — An automated image analysis system for the recognition and quantification of skin disease
Acne and rosacea are skin diseases that affect around 85% of individuals, the former being the most common skin condition afflicting up to 50 million people. There is no gold standard for evaluation of these skin diseases, and their treatment efficacy is generally determined according to a poorly …
  • College: College of Medicine (COM)
  • Inventors: Kaffenberger, Benjamin; Gurcan, Metin
  • Licensing Officer: Hampton, Andrew

Absolute Minimal Sampling of Homonuclear 2D NMR TOCSY Spectra for High-Throughput Applications of Complex Mixtures
TS-037865 — A technique to increase the processing speed of data collection without losing accuracy
Modern applications of 2D NMR spectroscopy for diagnostic screening, metabolomics, quality control, and other high-throughput applications are limited by the time-consuming sampling requirements. 2D Total Correlation Spectroscopy (TOCSY) provides unique spin connectivity information for the analys…
  • College: College of Arts & Sciences
  • Inventors: Bruschweiler, Rafael; Hansen, Alexandar "Alex"; Li, Dawei "Dawei"
  • Licensing Officer: Dahlman, Jason "Jay"

Remote Sensing Image Processing Algorithm for Assessing Plant Population at Emergence
TS-036544 — An algorithm that processes aerial images to provide farmers with data on crop emergence needed for improving crop management decisions.
The Need: In today's agriculture industry, the ability to make timely and informed crop management decisions is crucial for maximizing crop yield and profitability. However, the traditional methods of manual scouting and assessment are time-consuming and may not cover large areas effectively. T…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Wolters, Dustin; Leonard, James; See, David; Shearer, Scott
  • Licensing Officer: Dahlman, Jason "Jay"

Multi-carrier processing in auditory prosthetic devices
TS-014871 — Encoding strategy for improvement of speech understanding in a noisy environment for audiotory prosthetic devices.
There are about 275 million adults globally with moderate to severe hearing loss and 360 million adults with mild hearing loss. The current solutions to allow these people to hear better include hearing aids, hearing loss counseling, cochlear implants, alerting devices, and other communication aid…
  • College: College of Arts & Sciences
  • Inventors: Apoux, Frederic; Healy, Eric
  • Licensing Officer: Willson, Christopher

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