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Blending Proteins for Improved Functionality
TS-056508 — Although demand for natural, high-quality, and preservative-free protein beverages is growing, current methods for producing these products are limited. Therefore, new approaches that generate highly tunable and natural products are needed to support health-promoting lifestyles.
The Need Consumers have substantial demand for customizable liquid foods, beverages, and dietary solutions that will help them more aggressively meet their unique nutrition and personal health goals. While there are many methods for producing various formulations, there is high interest in liquid f…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Balasubramaniam, V M "Bala"; Janahar, Jerish; Jimenez-Flores, Rafael
  • Licensing Officer: Dahlman, Jason "Jay"

Isolation of an Ohio Porcine Epidemic Diarrhea Virus (PEDV) PC22A Strain in Cell Culture
TS-046905 — Porcine epidemic diarrhea virus (PEDV) has historically been an exotic disease to the U.S.. As of May, 2013, the virus made its way from China to the U.S.. This virus causes nearly 100% mortality in piglets and ranges from 80-90% morbidity. There is currently no PEDV vaccine in production. This inve…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Saif, Linda; Oka, Tomoichiro; Wang, Qiuhong
  • Licensing Officer: Dahlman, Jason "Jay"

Production of a stable blend of casein and plant proteins with improved physical and flavor characteristics
TS-046583 — This process creates a stable, desirable blend of casein and plant proteins that includes improvements on the physical and flavor characteristics of the blend. It has applications in areas such as dairy production, fitness supplements, and foods. With improved stability, flavor, and physical characteristics, it represents a needed improvement over current methods of casein and plant protein blending.
Food proteins have countless biological purposes, and the demand for protein has steadily increased in recent years. Meanwhile, however, dairy consumption has been decreasing. Dairy producers must therefore innovate in order to attract customers. Using currently available methods, the combination …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Jimenez-Flores, Rafael; Mayta Apaza, Alba; Ortega-Anaya, Joana; Tieu, Stiphany
  • Licensing Officer: Dahlman, Jason "Jay"

Isolated Milk Phospholipids and MFGM
TS-045170 — Process for isolating and producing a high milk phospholipid ingredient from a by-product of the dairy industry, also commonly known as Milk Fat Globule Membrane (MFGM).
Milk phospholipds are in demand in the food industry because they promote good gut health and cognitive development in adults and infants. Currently, phospholipids can be extracted from a high fat fraction of milk sweet whey. Unlike the sweet whey from natural cheese manufacturing, the acid whey f…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Jimenez-Flores, Rafael; Ortega-Anaya, Joana
  • Licensing Officer: Dahlman, Jason "Jay"

Method to improve natural rubber (hevea/guayule)-toughened poly-(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV) for food packaging applications
TS-044688 — Nearly all plastics that are used to produce packaging materials are petroleum-based and non-biodegradable. This makes their use undesirable to consumers in an increasingly sustainability-focused market. Therefore, the development of biologically-derived, biodegradable plastic for packaging materi…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Vodovotz, Yael; Cornish, Katrina; Koelling, Kurt; Venoor, Varun "varun"; Zhao, Xiaoying "Xiaoying"
  • Licensing Officer: Dahlman, Jason "Jay"

Antimicrobials to Control Campylobacter
TS-044474 — Campylobacter is a leading cause of foodborne disease in humans, affecting more than one million Americans each year. Campylobacteriosis is projected to remain one of the most-frequent causes of disease and death worldwide. Human infection primarily occurs by ingesting contaminated chicken, and tr…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Acuna, Ulyana Munoz; Antwi, Janet; Carcache de Blanco, Esperanza; Fuchs, James; Kumar, Anand; Nislow, Corey; Pascall, Melvin
  • Licensing Officer: Dahlman, Jason "Jay"

Small molecule modulators of Avian Pathogenic E. coli (APEC) virulence as a means to control avian collibacillosis
TS-040540 — Small molecules have been developed that have shown effective defense against Avian pathogenic Escherichia coli (APEC). These molecules can be used by itself, or with current antibiotics, which helps decrease the overall risk of bacterial antibiotic resistance.
Avian pathogenic Escherichia coli (APEC) is one of the most common poultry diseases that is characterized by a series of extra intestinal infections that effect the visceral organs of the bird. The disease affects chickens, turkeys, and other avian species, and highly reduces egg production and we…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Deblais, Loic; Kathayat, Dipak; Mohamed, Yosra
  • Licensing Officer: Dahlman, Jason "Jay"

Small molecule growth inhibitors of avian pathogenic E. coli (APEC) as a means to control APEC infections in poultry.
TS-039568 — Small molecules have been developed that have shown effective defense against Avian pathogenic Escherichia coli (APEC). These molecules can be used by itself, or with current antibiotics, which helps decrease the overall risk of bacterial antibiotic resistance.
Avian pathogenic Escherichia coli (APEC) is one of the most common poultry diseases that is characterized by a series of extra intestinal infections that effect the visceral organs of the bird. The disease affects chickens, turkeys, and other avian species, and highly reduces egg production and we…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Deblais, Loic; Kathayat, Dipak; Mohamed, Yosra
  • Licensing Officer: Dahlman, Jason "Jay"

Control of Salmonella in poultry using new generation small molecule growth inhibitors
TS-039567 — Small molecule compounds that can be used to inhibit Salmonella growth for safe and sustainable poultry production.
Non-typhoidal Salmonella are among the top five intestinal pathogens in the United States. Among foodborne illnesses, they are responsible for 11% of illnesses, 35% of those hospitalizations, and 28% deaths, with an estimated cost of $3.6 billion in 2014. Poultry is the most common source of wide-…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Deblais, Loic; Kathayat, Dipak; Miller, Sally; Mohamed, Yosra
  • Licensing Officer: Dahlman, Jason "Jay"

Novel Foam Collector for Bioreactors
TS-039273 — A foam collector to be used with bioreactors that would target and remove secondary metabolites produced and held within foam that is a product of the chemical reactions conducted.
Certain chemical reactions conducted in bioreactors, like aerobic fermentation, can produce a persistent foam that fills the headspace of the reactor vessels in which the reaction is taking place. This foam can be removed by introducing surface agents, but this is extremely undesirable as these ag…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Yousef, Ahmed; Campbell, Emily; Kasler, David
  • Licensing Officer: Dahlman, Jason "Jay"

Mucoadhesive Nanoparticle Entrapped Influenza Virus Vaccine Delivery System
TS-038882 — A mucoadhesive nonoparticle entrapped influenza virus vaccine delivery system for animals and humans.
As one of the top three swine respiratory health problems in the U.S., swine influenza virus (SIV) is a key concern for the industry. SIV – referred to as “swine flu” or “flu” – can be caused by a number of different swine influenza strains. SIV has evolved from…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Gourapura, Renukaradhya; Dhakal, Santosh; Renu, Sankar
  • Licensing Officer: Dahlman, Jason "Jay"

Composition and oral delivery of nanoparticle based Salmonella vaccine for poultry
TS-038337 — A Salmonella oral vaccine to provide mucosal immunity and reduce bacterial shedding in poultry.
Fifteen of every 100,000 people will contract salmonellosis annually in the United States, with a related cost of $3.6 million in economic and medical expenses. A single outbreak can quickly increase these costs - Alamosa, CO paid over $2.6 million in 2008 following an outbreak. The disease comes …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Gourapura, Renukaradhya; Renu, Sankar; Selvaraj, Ramesh
  • Licensing Officer: Dahlman, Jason "Jay"

Probiotic strains for reducing antibiotic resistance and modulating poultry gut health
TS-037818 — A novel advancement in food animal production to mitigate antibiotic resistance in the ecosystem.
Antibiotic resistance is a major challenge to human health worldwide. The broad uses of antibiotic resistance is considered key the problem seen today. Targeted mitigation of all antibiotic resistant bacteria is essential to achieve effective control of the current problem and also protection of h…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Wang, Hua; Wang, Zihua; Zhang, Lu; Zhou, Yang
  • Licensing Officer: Dahlman, Jason "Jay"

HM09-W150; Glycine max; Soybean
TS-037808 — HM09-W150 is a soybean (Glycine Max) variety.
HM09-W150 is a type of Soybean (Glycine Max), released by The Ohio State University in late April of 2015. It has a relative maturity of 3.0.
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: McHale, Leah; Dorrance, Anne; Feller, Marcia; McIntyre, Scott; Spring, Andrew; St Martin, Steven
  • Licensing Officer: Dahlman, Jason "Jay"

Cultivable Porcine Deltacoronavirus
TS-036864 — A cultivable porcine deltacoronavirus to act as a stepping stone for porcine deltacoronavirus vaccine development.
Currently, there is a lack of an effective vaccine to completely treat porcine deltacoronavirus (PDCoV), leaving many pigs vulnerable to the virus's adverse effects, including dehydration, diarrhea, and possible death. Thus, research and development methods and technologies that will improve s…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Saif, Linda; Hu, Hui
  • Licensing Officer: Dahlman, Jason "Jay"

OH­FD22 Cell Adapted Porcine Deltacoronavirus (PDCoV) Strain
TS-036630 — This invention details the virus isolate that has been developed from methods derived at The Ohio State University.
Porcine deltacoronavirus (PDCoV) is a novel coronavirus that causes diarrhea in nursing piglets. In extreme cases, these piglets died following infection. PDCoV is similar to other transmissible viruses in porcine populations, but is not transmissible to humans. Following its first detection in the …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Saif, Linda; Hu, Hui
  • Licensing Officer: Dahlman, Jason "Jay"

Unmanned Aerial System Stinger-Suspended Crop Health Sensing
TS-036526 — A remote sensing imaging system that combines a suspended camera with sampling probes, combined with unique image processing features.
Unmanned Aerial Systems (UAS) allow agricultural producers to generate high-resolution crop health data over large areas. UAS generate this data by imaging the upper canopy while flying above row crops. However, most crop health problems originate below the upper portion of the canopy. Most causes…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Shearer, Scott; Klopfenstein, Andrew "Andrew"; See, David; Weigman, Christopher
  • Licensing Officer: Dahlman, Jason "Jay"

Small Molecule Modulators as a Means to Control Tomato Bacterial Canker
TS-014936 — Small molecule modulators of Clavibacter michiganensis subsp. michiganensis (Cmm) as a means to control tomatobacterial canker.
Current efforts to control tomato cankers rely heavily on copper bactericides and antibiotics. These methods have significant limitations in that they exhibit limited efficacy in treatment and may promote pathogen resistance. Common strategies for controlling tomato bacterial canker mainly rely on…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Fuchs, James; Miller, Sally; Nislow, Corey; Xu, Xiulan
  • Licensing Officer: Dahlman, Jason "Jay"

Spray Acid Wet Scrubbers to Recover Ammonia Emission from Poultry
TS-014832 — A novel, cost effective ammonia scrubber for use in commercial poultry facilities.
Ammonia emissions pose a threat to environmental quality, public health, and agricultural operations. Ammonia gas (NH3) is a waste product from animal production and manure composting facilities, and contributes to environmental acidification and increase particulate concentrations in the air. The…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Zhao, Lingying; Hadlocon, Lara Jane; Manuzon, Roderick
  • Licensing Officer: Dahlman, Jason "Jay"

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