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Column-free Purification of Recombinant Proteins
TS-064270 — Large-scale recombinant proteins in Gram-negative bacteria (i.e., E. coli) are of significant interest in recombinant protein/enzyme production. These proteins exhibit wide-ranging applications, including food and beverages, conversion of carbohydrates into fuel ethanol or biodiesel, components for …
  • College: College of Arts & Sciences
  • Inventors: Gopalan, Venkat
  • Licensing Officer: Willson, Christopher

RNA-TetherTech: Revolutionizing In Vivo Post-Transcriptional Gene Regulation
TS-064267 — In the field of post-transcriptional gene regulation, understanding the functions of RNA-binding proteins is crucial for controlling cellular processes and development in organisms. However, the lack of reliable tools for studying these proteins in vivo, particularly in plant cells, has hindered p…
  • College: College of Arts & Sciences
  • Inventors: Cuerda Gil, Diego
  • Licensing Officer: Willson, Christopher

Novel Small Molecule for Saltiness Enhancement
TS-064188 — The Need: In a world grappling with the consequences of poor dietary choices, the imperative to address the global health crisis has never been more critical. Poor diets contribute to 1 in 5 deaths globally, with non-optimal sodium intake being a primary culprit. The USDA recommends a reduction of …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Peterson, Devin; Tello Camacho, Edisson; Wang, Irene
  • Licensing Officer: Dahlman, Jason "Jay"

Small molecules that suppress heat/pain perception
TS-064187 — The Need In the culinary and pharmaceutical realms, the need for a groundbreaking solution to modulate flavor and alleviate sensory perceptions is crucial. Businesses seek innovative ways to enhance consumer experiences by addressing pungency in foods and alleviating burn or pain sensations in phar…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Peterson, Devin; borcherding, Joel
  • Licensing Officer: Dahlman, Jason "Jay"

A modernized fermentation process (Helenization) to improve the safety and quality of fermented fruits, vegetables and meats, etc.
TS-064186 — The Need: In the realm of traditional food fermentation, there exists a critical need to address safety and quality inconsistencies associated with artisan processes, particularly the transmission of antibiotic-resistant (AR) bacteria through fermented products. Conventional methods often result in …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Wang, Hua; Fu, Siying; Li, Yutong
  • Licensing Officer: Dahlman, Jason "Jay"

Improved Varroa Mite Control: Enhanced Efficacy of Extended-Release Oxalic Acid for Honeybee Colonies
TS-064184 — Varroa mites are a significant threat to honeybee colonies, presenting a formidable challenge in apiculture and prompting widespread concern among beekeepers and researchers. Infiltrating honeybee hives and feeding on adult bees and their brood, varroa mites eventually lead to colony collapse. Beyon…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Johnson, Reed; Shannon, Brandon
  • Licensing Officer: Wilburn, Adri

Increasing Latex Production From Crops
TS-064180 — The global market for natural rubber, totaling 14 million tons annually, is experiencing a shift driven by the European goal of achieving 20% self-supply. This objective aims to reduce dependency on hevea natural rubber, predominantly sourced from Asian countries. While the Kazakh dandelion (Tarax…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Cornish, Katrina
  • Licensing Officer: Dahlman, Jason "Jay"

The Next Wave in Gluten-Free, Clean Label Meat and Cheese Analogues
TS-064178 — The Need: In the ever-evolving landscape of plant-based protein alternatives, the demand for gluten-free, clean label options that authentically mimic the textural properties of traditional meat and cheese products is at an all-time high. Current analogues, despite advancements, fall short in cohesi…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Campanella, Osvaldo; Munoz Salgado, Andres
  • Licensing Officer: Dahlman, Jason "Jay"

Automated Plant DNA Extraction for Portable Genomic Sequencing
TS-063963 — The Need In the dynamic realm of space exploration, the imperative to sustain life during extended missions places a critical demand on understanding the impact of spaceflight on plant growth. Traditional DNA sequencing methods employed by NASA fall short when dealing with plant material, necessita…
  • College: College of Engineering (COE)
  • Inventors: Brozovich, Cassidy; Ling, Peter; Tkach, Chris
  • Licensing Officer: Randhawa, Davinder

Improved methods for extracting latex from rubber dandelion (Taraxacum kok-saghyz) roots
TS-063460 — The Need: In a world driven by innovation and sustainability, the demand for natural rubber (NR) continues to surge across a multitude of industries, including automotive, healthcare, and construction. NR's unparalleled properties, unmatched by synthetic alternatives, make it an indispensable c…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: King-Smith, Nate; Cornish, Katrina
  • Licensing Officer: Dahlman, Jason "Jay"

Improved methods for extracting latex from rubber dandelion (Taraxacum kok-saghyz) roots
TS-063458 — The Need: In a world driven by innovation and sustainability, the demand for natural rubber (NR) continues to surge across a multitude of industries, including automotive, healthcare, and construction. NR's unparalleled properties, unmatched by synthetic alternatives, make it an indispensable c…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Cornish, Katrina; Blakeslee, Joshua; King-Smith, Nate
  • Licensing Officer: Dahlman, Jason "Jay"

Part 3 of 3: Fluidic Oscillators with Three-Dimensional Output
TS-063372 — Embark on a new era of fluidic control with our state-of-the-art three-dimensional fluidic oscillator technology. Experience precision, versatility, and efficiency like never before. Stay ahead of the curve and revolutionize your industry with our innovative solution. This inventive design is 1 of 3 aspects of technology T2019-309 and is just one part of a larger, comprehensive suite of fluidic oscillator technologies offered by The Ohio State University for licensing. To learn more about our other designs, please visit https://oied.osu.edu/find-technologies and search using the term: Fluidic Oscillator. To see a descriptive YouTube video of this technology, please visit: https://www.youtube.com/watch?v=g2Hn2q5W958.
In the realm of fluidic devices, the demand for a three-dimensional oscillating fluid stream has been a persistent challenge. Conventional fluidic oscillators, while efficient, produce a limited two-dimensional output. There is a critical commercial need for a fluidic oscillator that can break fre…
  • College: College of Engineering (COE)
  • Inventors: Tomac, Mehmet
  • Licensing Officer: Zinn, Ryan

Part 2 of 3: Fluidic Oscillators with Atomized Output
TS-063369 — Experience the future of atomization technology with our feedback type fluidic oscillator device with atomized output. Unlock unparalleled precision and efficiency in fluid dispersion, revolutionizing industries and setting new standards for atomized spray applications. This inventive design is 1 of 3 aspects of technology T2019-309 and is just one part of a larger, comprehensive suite of fluidic oscillator technologies offered by The Ohio State University for licensing. To learn more about our other designs, please visit https://oied.osu.edu/find-technologies and search using the term: Fluidic Oscillator. To see a descriptive YouTube video of this technology, please visit: https://www.youtube.com/watch?v=g2Hn2q5W958.
In the realm of fluid dynamics, there is a pressing commercial need for atomizing devices that can produce fine particles in all three dimensions. Current atomizers are limited, primarily offering two-dimensional sprays with little dispersion in the third dimension. Industries spanning from fuel i…
  • College: College of Engineering (COE)
  • Inventors: Tomac, Mehmet
  • Licensing Officer: Zinn, Ryan

Part 1 of 3: Fluidic Oscillators with Sweeping Jets and Multidirectional Output
TS-063350 — Experience the future of fluidic control—our sweeping jet device with multidirectional output sets a new standard in precision fluid distribution, offering reliability, efficiency, and innovation for diverse industrial applications. This inventive design is 1 of 3 aspects of technology T2019-309 and is just one part of a larger, comprehensive suite of fluidic oscillator technologies offered by The Ohio State University for licensing. To learn more about our other designs, please visit https://oied.osu.edu/find-technologies and search using the term: Fluidic Oscillator. To see a descriptive YouTube video of this technology, please visit: https://www.youtube.com/watch?v=g2Hn2q5W958.
In various industrial applications, the demand for versatile fluidic systems capable of delivering multidirectional sweeping outputs has become crucial. Traditional jet interaction-type fluidic oscillators, while efficient, face limitations when it comes to covering wide, multidirectional fields w…
  • College: College of Engineering (COE)
  • Inventors: Tomac, Mehmet
  • Licensing Officer: Zinn, Ryan

Hemp (Cannabis sativa) Isolated Compounds for Controlling Pests
TS-062422 — The Need In modern agriculture and pest management practices, there is a growing demand for effective insecticides that are environmentally friendly and sustainable. Conventional synthetic insecticides can have adverse effects on ecosystems, non-target species, and human health. Therefore, there is…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Piermarini, Peter; Canas, Luis; Rakotondraibe, Harinantenaina Liva
  • Licensing Officer: Dahlman, Jason "Jay"

Advanced Biopesticides and Bio Stimulants for Sustainable Crop Protection and Growth Enhancement
TS-062409 — The Need: In the face of climate change and the diminishing efficacy of conventional pest control methods, the agricultural industry is in dire need of sustainable solutions to protect and enhance crop growth. The escalating disease pressure calls for innovative technologies that can bolster a plant…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Wang, Guo-Liang; Bhat, Prabhat; Pei, Dehua; Wang, Jiyang
  • Licensing Officer: Dahlman, Jason "Jay"

A Novel African Swine Fever Vaccine
TS-062364 — The Need: Addressing the Threat of African Swine Fever Virus (ASF) African swine fever (ASF) presents a severe commercial burden given the highly contagious and deadly nature of the viral disease. With no existing treatment or vaccine available, ASF outbreaks have devastated domestic and feral pig …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Kenney, Scott; Gourapura, Renukaradhya
  • Licensing Officer: Dahlman, Jason "Jay"

Chemical Drivers of Vanilla Flavor Liking - Unlocking the Secrets of Vanilla's Irresistible Allure
TS-062251 — The Need: Vanilla, a beloved and widely used flavoring agent, owes its popularity to its unique and highly desirable taste profile. The traditional curing process for vanilla beans, while effective, is labor-intensive and time-consuming, taking up to nine months. The quest for quicker curing methods…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Peterson, Devin; Forero Arcila, Diana Paola; Peterson, Julie; Tello Camacho, Edisson
  • Licensing Officer: Dahlman, Jason "Jay"

Single-Pass Harvester for Whole-Plant Crops
TS-062238 — The Need: As the United States strives to transition its energy reliance from traditional fossil fuels to renewable sources, the need for efficient and sustainable feedstock procural for cellulosic and lignocellulosic ethanol production becomes paramount. To achieve this goal, a technology that can…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Shearer, Scott; Klopfenstein, Andrew "Andrew"; Parsons, Nate; Shah, Ajay
  • Licensing Officer: Dahlman, Jason "Jay"

Compounds that enhance the desirable flavor of coffee
TS-062237 — The Need In the rapidly evolving specialty coffee industry, the demand for higher flavor quality coffee has become a key driver for success. Coffee producers and retailers are facing the challenge of consistently delivering exceptional coffee experiences to meet the discerning tastes of consumers. …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Peterson, Devin; Linne, Brianne; Simons, Christopher; Tello Camacho, Edisson
  • Licensing Officer: Dahlman, Jason "Jay"

FrostShield : Protecting Plants and Crops from Frost Damage
TS-062236 — The Need: Spring frost damage poses a significant challenge for viticulture regions worldwide, resulting in crop losses, delayed fruit ripening, and economic hardships. With climate change causing earlier budbreak in wine-growing regions, grapevines are increasingly susceptible to frost damage. Conv…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Dami, Imed
  • Licensing Officer: Dahlman, Jason "Jay"

Plant-based beverages with EPA and DHA from non-fish sources
TS-062233 — The Need: The increasing awareness of the health benefits associated with fish oil and its fatty acid components, such as EPA and DHA, has resulted in a demand for dietary supplements that can provide these beneficial compounds. However, various factors, including allergies, dietary restrictions, an…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Sommer, Abigail; Vodovotz, Yael
  • Licensing Officer: Dahlman, Jason "Jay"

Plasticized biopolymer compositions and their methods of production
TS-062230 — The Need The need for this technology arises from the limitations of existing bioplastics. While bioplastics show promise due to their renewable and biodegradable properties, they are often brittle and difficult to process, which restricts their use in various industrial applications. Despite effor…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Vodovotz, Yael; Chatzakis, Emmanouil; Williamson, Kathryn; Zhao, Xiaoying "Xiaoying"
  • Licensing Officer: Dahlman, Jason "Jay"

Novel Antimicrobial peptides effective against avian pathogenic Escherichia coli (APEC) and Salmonella
TS-062229 — The Need: Microbial infections, particularly those caused by antibiotic-resistant pathogens like APEC and Salmonella, pose a significant commercial and health challenge. The demand for effective and innovative bioactive peptides capable of inhibiting these pathogens is escalating. Biotechnology comp…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Closs, Gary; FNU, Dhanashree; Kathayat, Dipak
  • Licensing Officer: Dahlman, Jason "Jay"

Enhanced anthocyanin-based colorants
TS-062228 — The Need The food industry is actively seeking alternatives to synthetic colorants due to consumer concerns over their safety and increasing legal challenges. Natural colorants, particularly anthocyanins found in fruits, vegetables, grains, and flowers, offer potential health benefits and a wide ra…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Giusti, M. Monica; Zhou, Yucheng
  • Licensing Officer: Dahlman, Jason "Jay"

Identification of Bacteria That Promote Plant Growth with Low Fertilizer Inputs.
TS-062225 — The Need: Enhancing Greenhouse Ornamental Crop Production with Plant Growth Promoting Rhizobacteria (PGPR) In the competitive and environmentally-conscious market of greenhouse ornamental crop production, the need for sustainable and efficient cultivation methods has become increasingly paramount. …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Jones, Michelle; Chapin, Laura; Nordstedt, Nathan; South, Kaylee
  • Licensing Officer: Dahlman, Jason "Jay"

Bacterial Strains that can Improve Water Stress Tolerance in Plants
TS-062223 — The Need: Increasing Resilience of Ornamental Crops to Water Stress Ornamental crop growers face significant challenges due to water deficit stress, which negatively impacts plant growth, flowering, and overall crop quality. Water stress during both production and post-production phases can result …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Jones, Michelle; Chapin, Laura; Nordstedt, Nathan
  • Licensing Officer: Dahlman, Jason "Jay"

Beneficial bacteria for the control of Botrytis cinerea in greenhouse crops
TS-062222 — The Need: In the commercial greenhouse industry, the heavy reliance on chemical pesticides for ornamental plant production raises growing concerns regarding environmental contamination and safety. With increased interest in sustainable and safer alternatives, there is a demand for effective pest co…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Jones, Michelle; Chapin, Laura; Hand, Francesca; South, Kaylee; Taylor, Christopher
  • Licensing Officer: Dahlman, Jason "Jay"

Ultra Sheer Technology (UST): Transforming Protein Blending for Superior Nutrition and Taste
TS-062221 — The Need: The food industry faces the challenge of meeting increasing consumer demand for health-promoting, sustainable, and cost-effective protein-based diets. While plant-based milk products have gained popularity, many consumers are hesitant due to undesirable flavors and compromised taste. Addit…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Balasubramaniam, V M "Bala"; Janahar, Jerish Joyner; Jimenez-Flores, Rafael
  • Licensing Officer: Dahlman, Jason "Jay"

Nanoparticle Vaccine to combat Necrotic enteritis in poultry
TS-062219 — The Need: Addressing the Global Threat of Necrotic Enteritis in Poultry Necrotic enteritis (NE) poses a significant commercial challenge to the poultry industry, with estimated annual costs reaching up to 5-6 billion USD worldwide. The disease, caused by Clostridium perfringens, affects broilers, l…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Gourapura, Renukaradhya; Renu, Sankar
  • Licensing Officer: Dahlman, Jason "Jay"

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