TS-063963 — The Need In the dynamic realm of space exploration, the imperative to sustain life during extended missions places a critical demand on understanding the impact of spaceflight on plant growth. Traditional DNA sequencing methods employed by NASA fall short when dealing with plant material, necessita…

TS-062762 — Pinpointing previously concealed sectoral differences in the diabetic retina to diagnose DR earlier.

TS-062628 — More than a billion people worldwide suffer from some neurological disorders, such as Alzheimer's, Parkinson's, multiple sclerosis, epilepsy, stroke, autism, addiction, and many others. These conditions result in more than 7 million deaths, with associated costs exceeding $1.5 trillion annua…

TS-062627 — Magnetic Resonance Imaging (“MRI”) is one of the most important modern medical imaging modalities. It has far less risk of side effects than most other imaging modalities. Generally, a high quality image requires high signal-to-noise ratio, high contrast between normal and pathological t…

TS-062555 — The Need: Improved Nucleic Acid Detection Probes There is a growing need for advanced detection probes that can effectively identify target nucleic acid sequences while reducing binding to mismatched targets. Existing technologies often suffer from false positive results due to temperature fluctuat…

TS-062553 — The Need The swift and accurate diagnosis of COVID-19 and other viruses is crucial in preventing their spread. Current detection methods like PCR and antibody testing have limitations, including long run times, sample preparation, and high false negative rates. Moreover, with the rapid mutation and…

TS-062547 — The Need: The field of molecular biology and genetic engineering faces challenges in achieving precise and accurate detection and amplification of target nucleic acid sequences. Traditional hybridization technologies suffer from the issue of mismatched targets, leading to reduced specificity and rel…

TS-062493 — Children whose heights or growth rates fall outside of the normal range can be identified as having short stature (less than the 3rd percentile) or tall stature (above the 97th percentile) or as having abnormal growth velocity. Serial height measurements over time are key to identifying these patt…

TS-062335 — The Need: In the field of ophthalmology and vision care, there is a critical need for accurate and comprehensive measurements of visual function over the entire visual field. Conditions such as glaucoma, age-related macular degeneration (AMD), diabetes, stroke, pituitary disease, brain tumors, and n…

TS-060782 — Problem Statement: Diagnosis of arterial occlusion and an associated stroke can be lengthy, delaying patient access to treatment. As large vessel occlusions account for 24 to 46% of acute ischemic strokes and may require treatment in a comprehensive stroke center, early diagnosis is key. Solution:…

TS-059578 — A novel biomarker for the early identification of cardiac damage, including chemotherapy-induced cardiotoxicity.

TS-059537 — An untargeted NMR-based metabolomics approach to identify metabolic compounds as signatures of bacterial joint infections and methods for the treatment and prevention thereof.

TS-050296 — A sequencing-based diagnostic assay for SARS-CoV-2 with sensors of immune activation and the viral microbiota.

TS-043819 — Compositions and methods for analyzing multiple biomarkers without damaging tissue.

TS-039267 — A non-invasive and automated tumor budding image analysis system for colorectal cancer. This program can detect tumor buds in traditional H&E stained sections without the need for manual assessment.

TS-038604 — Apparatus and methods to form three-dimensional dried blood spheroids on hydrophobic paper substrates.

TS-038429 — An automated image analysis system for the recognition and quantification of skin disease

TS-038384 — A novel device for monitoring cancer cell motility in real time using standard microscopy.

TS-038065 — OSU­-SpARKFUSE is an RNA sequencing assay that detects known and novel gene fusion mutations in multiple cancer types.

TS-037865 — A technique to increase the processing speed of data collection without losing accuracy

TS-037470 — A novel method of measuring the time course of degradation of perceptual sensitivity due to disease

TS-037383 — Functional "fingerloop" RNA antisense motifs for metabolic engineering and RNA nanotechnology applications.

TS-014895 — Identified gene target for treatment of human acute leukemia, brain tumors and melanoma