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Isolation of Porcine Epidemic Diarrhea Virus (PEDV) strain Iowa106
TS-044567 — Porcine epidemic diarrhea virus (PEDV) appeared in the US in 2013 and has spread rapidly throughout North America. The virus causes gastroenteric disease in adults and is fatal to nursing piglets, whose only protection from the disease is via passive immunity from their mother. Currently, most US …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Wang, Qiuhong; Oka, Tomoichiro; Saif, Linda
  • Licensing Officer: Dahlman, Jason "Jay"

Cultivable Porcine Deltacoronavirus
TS-036864 — A cultivable porcine deltacoronavirus to act as a stepping stone for porcine deltacoronavirus vaccine development.
Currently, there is a lack of an effective vaccine to completely treat porcine deltacoronavirus (PDCoV), leaving many pigs vulnerable to the virus's adverse effects, including dehydration, diarrhea, and possible death. Thus, research and development methods and technologies that will improve s…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Saif, Linda; Hu, Hui
  • Licensing Officer: Dahlman, Jason "Jay"

OH­FD22 Cell Adapted Porcine Deltacoronavirus (PDCoV) Strain
TS-036630 — This invention details the virus isolate that has been developed from methods derived at The Ohio State University.
Porcine deltacoronavirus (PDCoV) is a novel coronavirus that causes diarrhea in nursing piglets. In extreme cases, these piglets died following infection. PDCoV is similar to other transmissible viruses in porcine populations, but is not transmissible to humans. Following its first detection in the …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Saif, Linda; Hu, Hui
  • Licensing Officer: Dahlman, Jason "Jay"

Methods to Improve Mucosal Immune Response During Vaccination
TS-015239 — A method for enhancing the mucosal (IgA) immune response by transiently blocking a specific cellular subset during vaccination.
Mucosal IgA are immunoglobulins (antibodies) that play a key role in the defense of mucosal tissues by neutralizing pathogenic microorganisms and toxins and interfering with bacterial or viral colonization of the epithelium. An important component of needle-free vaccines is induction of mucosal Ig…
  • College: College of Veterinary Medicine
  • Inventors: Boyaka, Prosper
  • Licensing Officer: Dahlman, Jason "Jay"

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