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Metabolic Engineering of Clostridium Tyrobutyricum for Butanol Production
TS-037555 — A new strain of bacteria that can produce butanol at a high titer for transportation fuel.
Butanol is generally used as an industrial solvent but can also be blended with gasoline and used as transportation fuel. Butanol is commonly produced using fossil fuels, but it can also be produced from biomass, referred to as biobutanol. Biobutanol is produced from fermentation of the same feeds…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Yu, Mingrui
  • Licensing Officer: Paschall, Christopher

N-Proanol and Propionic Acid Producing Propionibacteria
TS-037515 — New method of producing n-propanol and propionic acid using a metabolically engineered propionibacteria.
Propionibacteria are well-known for their various industrial applications including the manufacturing of Swiss cheese, vitamin B12, and propionic acid. However, not much is known about their genetics, and few studies have been conducted utilizing them for metabolic engineering, mostly in vitamin B…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Ammar, Ehab
  • Licensing Officer: Paschall, Christopher

Ultrathin Layer Chromatography Plates using Carbon Nanoparticles
TS-015316 — Carbon nanoparticle-filled polyacrylonitrile electrospun stationary phase for ultrathin layer chromatography (UTLC)
Carbon materials have been widely used as stationary phase in separation science due to their unique selectivity and stability. The wide variety of potential intermolecular interactions that can occur between carbon surfaces and target analytes makes carbon stationary phases applicable to a wide v…
  • College: College of Arts & Sciences
  • Inventors: Olesik, Susan; Fang, Xin
  • Licensing Officer: Dahlman, Jason "Jay"

Molecularly Imprinted Pyrolyzed Photoresist - A Molecularly Imprinted Carbon
TS-015282 — A thermo-stable, durable, and highly selective molecular carbon template for solid phase extraction/microextraction.
Molecularly Imprinted Polymers (MIPs) are robust molecular recognition elements able to mimic natural recognition entities, such as antibodies and biological receptors, useful to separate and analyze complicated samples such as biological fluids and environmental samples. This is a commonly utiliz…
  • College: College of Arts & Sciences
  • Inventors: Olesik, Susan; Zewe, Joseph
  • Licensing Officer: Dahlman, Jason "Jay"

Self-Assembly of Camptothecin-Peptide Nanostructures
TS-014812 — An improved delivery mechanism has been developed for camptothecin derivatives which will increase chemotherapeutic efficacy.
Many cancer therapeutics exhibit extremely toxic side effects or have limited efficacy due to low bio-availability. Existing drug delivery technologies can add excessive mass to the therapeutic, grossly expanding the dosage necessary for response. Camptothecin (CPT) is a naturally occurring compou…
  • College: College of Arts & Sciences
  • Inventors: Parquette, Jonathan; Grinstaff, Mark; Kaplan, Jonah; Kim, Se Hye
  • Licensing Officer: Flammang, Ann Marie

Butanol Production from Renewable Biomass
TS-014747 — A genetically engineered bacteria pathway directed to selectively generate butanol over competing by-products.
Acetone-Butanol-Ethanol (ABE) Fermentation is one of two methods to produce butanol from biomass feedstocks. Various active enzymes or acids are exposed to a biomass feedstock and subsequently produce primarily acetone, butanol and ethanol. Previous attempts in the industry to use Clostridium stra…
  • College: College of Arts & Sciences
  • Inventors: Yang, Shang-Tian "ST"; Zhao, Jingbo
  • Licensing Officer: Paschall, Christopher
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