Safeguarding Swine Health with a Recombination-Resistant PEDV Vaccine
TS-070563 — Protect neonatal piglets with a genetically stable, live attenuated vaccine that eliminates recombination risk and boosts immunity.
Overview
Despite ongoing vaccination efforts, PEDV continues to challenge swine producers with outbreaks that compromise piglet survival and herd productivity. Existing live attenuated vaccines, while immunogenic, are constrained by recombination and reversion risks, limiting their safety and re…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Wang, Qiuhong; Liu, Mingde
- Licensing Officer: Panic, Ana
A Novel African Swine Fever Vaccine
TS-062364 — The Need: Addressing the Threat of African Swine Fever Virus (ASF)
African swine fever (ASF) presents a severe commercial burden given the highly contagious and deadly nature of the viral disease. With no existing treatment or vaccine available, ASF outbreaks have devastated domestic and feral pig …
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Kenney, Scott; Gourapura, Renukaradhya
- Licensing Officer: Panic, Ana
Nanoparticle Vaccine to combat Necrotic enteritis in poultry
TS-062219 — The Need: Addressing the Global Threat of Necrotic Enteritis in Poultry
Necrotic enteritis (NE) poses a significant commercial challenge to the poultry industry, with estimated annual costs reaching up to 5-6 billion USD worldwide. The disease, caused by Clostridium perfringens, affects broilers, l…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Gourapura, Renukaradhya; Renu, Sankar
- Licensing Officer: Panic, Ana
A liposomal subunit flu vaccine formulation
TS-062211 — The Need: Addressing the Limitations of Current Flu Vaccines
Influenza epidemics and pandemics present significant challenges to public health and global economies. Existing flu vaccines are strain-specific, providing limited cross-protective immunity and often lack long-term effectiveness. Additio…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Gourapura, Renukaradhya; Carson, Kennith; Cheng, Xingguo; Dhakal, Santosh; Lee, Chang Won; McDonough, Joseph
- Licensing Officer: Panic, Ana
Mannose Conjugated Chitosan-Based Swine Influenza Vaccine
TS-060542 — The Problem
Swine influenza is an acute respiratory disease of pigs caused by swine influenza A virus (SwIAV). Pigs are naturally vulnerable to SwIAV-associated with secondary bacterial infections and is an economic threat to the global pig industry. Commonly circulating SwIAV strains in swine popu…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Gourapura, Renukaradhya
- Licensing Officer: Panic, Ana
Antibiotics Alternatives for Controlling Foodborne Diseases; APEC and Salmonella
TS-052320 — The Need
Avian pathogenic Escherichia coli (APEC) and Salmonella infections in poultry pose a significant commercial and health challenge. Current treatments relying on antimicrobial drugs have limited effectiveness and contribute to the emergence of antibiotic-resistant strains, exacerbating the p…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Rajashekara, Gireesh; Closs, Gary; Kathayat, Dipak
- Licensing Officer: Panic, Ana
Composition and oral delivery of nanoparticle based Salmonella vaccine for poultry
TS-038337 — A Salmonella oral vaccine to provide mucosal immunity and reduce bacterial shedding in poultry.
The Need: Salmonellosis, caused by Salmonella enterica serovar enteritidis (S. enteritidis), poses a significant health threat to both humans and poultry worldwide. It leads to substantial economic losses in the poultry industry and millions of deaths annually due to acute gastroenteritis and diarrh…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Gourapura, Renukaradhya; Renu, Sankar; Selvaraj, Ramesh
- Licensing Officer: Panic, Ana