# of Displayed Technologies: 60 / 692


Categories

Innovative Solutions for Cell Viability and Targeted Delivery
TS-066100 — Research tool to transfect cells ex vivo using electroporation through electrospun core-shell fibers for research applications
The Need: Conventional electroporation methods often result in low cell viability due to heat generation, especially when working with primary cells. These methods also face challenges with non-specific transport of molecules, high vector integration rates leading to mutagenesis, and inefficacy in …
  • College: College of Engineering (COE)
  • Inventors: Gallego Perez, Daniel; Das, Devleena; Duarte Sanmiguel, Silvia; Higuita Castro, Natalia
  • Licensing Officer: Schultz, Teri

A Cybersecurity Vulnerability Prioritization System Including Identifying "Super-Critical" Vulnerabilities, predicting "Dark Host" Vulnerabilities, and Addressing Economic Costs
TS-066063 — Our cybersecurity vulnerability maintenance system stands as a pillar of modern security strategy, transforming reactive security measures into a preemptive defense mechanism. This integration of technology and economics ensures that your most critical assets are protected efficiently and effectively, making it an invaluable tool for any organization serious about security.
In today’s hyper-connected world, the escalation in cyber threats poses significant risks to organizational data and systems. Vulnerabilities within network infrastructures can lead to massive security breaches, as demonstrated by incidents like the 2017 Equifax hack. Effective vulnerability…
  • College: College of Engineering (COE)
  • Inventors: Allen, Theodore; Liu, Enhao
  • Licensing Officer: Zinn, Ryan

SimulationAI -- AI-Enabled Software Solution for Physics-Based Simulations
TS-066058 — By adopting our AI-driven solution, engineering teams can achieve more in less time, push the boundaries of innovation, and significantly cut down costs, all while maintaining or increasing the reliability and accuracy of their structural and material analysis. This is not just an evolution in FEM technology—it's a revolution.
In an era where precision and efficiency drive the success of engineering projects, the finite element method (FEM) remains indispensable but is burdened by high operational and computational costs. These costs often lead to overlooked uncertainty factors, suboptimal designs, and significant finan…
  • College: College of Engineering (COE)
  • Inventors: Soghrati, Soheil; vemparala, Balavignesh; Yang, Ming
  • Licensing Officer: Zinn, Ryan

Synthetic approaches for mitigating battery capacity loss in oxide anodes
TS-066056 — The Need The advancement of lithium-ion battery technology relies heavily on increasing energy density, yet practical usage of silicon (Si) anodes faces challenges due to parasitic side reactions and active lithium consumption. Controlling lithium amounts precisely while achieving uniform distribut…
  • College: College of Arts & Sciences
  • Inventors: Co, Anne; Hwang, Jisun; Lorie Lopez, Jose
  • Licensing Officer: Randhawa, Davinder

T-cells with Enhanced Ability to Respond to Exogenous Ligands
TS-066052 — Novel T-cells expressing the IL-2a receptor to enhance cancer cell targeting.
The Need As interest in cell-based therapies, particularly for cancer treatment, continues to rise, there’s a critical need for therapeutic cells capable of robust proliferation in vivo. Existing methods relying on exogenous cytokines like IL-2 face challenges due to dose-limiting toxicity an…
  • College: OSU Wexner Medical Center
  • Inventors: Rubinstein, Mark
  • Licensing Officer: Schultz, Teri

Novel Antibodies Targeting IL-2
TS-066051 — Novel antibodies targeting IL-2 with the ability to inhibit IL-2 signaling through IL-2 Rαβg to a greater extent than through IL-2 Rβg.
IL-2 and its receptor IL-2R are known to play multiple roles in shaping the immune response, including both immune activation and tolerance. Expression of intermediate-affinity IL-2 receptors by different immune cell subsets determines cellular sensitivity to IL-2. However, the dynamic interplay bet…
  • College: OSU Wexner Medical Center
  • Inventors:
  • Licensing Officer: Schultz, Teri

Anode synthesis using spray pyrolysis
TS-066037 — The Need In the realm of materials science and energy storage, there's a growing demand for innovative anode synthesis methods that yield materials with improved mechanical and electrochemical properties. Traditional synthesis techniques often fall short in achieving the desired performance met…
  • College: College of Arts & Sciences
  • Inventors: Co, Anne; Lorie Lopez, Jose
  • Licensing Officer: Randhawa, Davinder

Metal nitric oxides redox flow batteries
TS-066016 — The Need Redox flow batteries (RFBs) offer a promising solution for storing intermittent renewable energy in the electrical grid. However, their reliance on finite and unsustainable transition metals, such as vanadium, poses significant sustainability challenges. The rising costs and environmental …
  • College: College of Arts & Sciences
  • Inventors: Zhang, Shiyu; Park, Jaehyun
  • Licensing Officer: Randhawa, Davinder

Designing High-Donicity Anions for Rechargeable Potassium Superoxide/Peroxide Batteries
TS-066015 — The Need Over the past two decades, the advancement of metal-O2 batteries has been hindered by issues of instability, reversibility, and poor energy efficiency, primarily due to the instability of superoxide in the presence of Li+ and Na+ ions. Existing solutions such as Li-O2 and Na-O2 batteries h…
  • College: College of Arts & Sciences
  • Inventors: Wu, Yiying
  • Licensing Officer: Randhawa, Davinder

Gene Therapy Approach for Treating Neuropathy
TS-065913 — Gene therapy strategies for treating peripheral neuropathy.
Peripheral neuropathy (PN) results in loss of innervation by the peripheral nerves in tissues such as skin, muscle, heart, and adipose tissue. It is a painful, debilitating disease, that is estimated to affect between 20 and 30 million Americans. The number of Americans affected by PN is likely muc…
  • College: College of Medicine (COM)
  • Inventors: Townsend, Kristy; Blaszkiewicz, Magdalena; Cao, Lei
  • Licensing Officer: Schultz, Teri

System for automated high-speed imaging and genetic manipulation of C. elegans on agar media
TS-065892 — The Need The microscopic worm C. elegans is a model animal studied in more than 1500 biological and medical research laboratories worldwide due to its genetic manipulability and optical transparency. In C. elegans research, the manual process of picking worms between plates presents a significant …
  • College: College of Engineering (COE)
  • Inventors: Fang-Yen, Christopher "Chris"; Alhalbi, Serge; Li, Zihao
  • Licensing Officer: Randhawa, Davinder

Use of Potassium Permanganate to Remediate Pb and carcinogenic polyaromatic hydrocarbons (cPAH) in Urban Contaminated Soil
TS-065863 — The Need: Contaminated vacant lots pose significant environmental and health risks in urban areas, especially in lower-income neighborhoods. Anthropogenic activities such as mining, industrial processes, and combustion lead to the accumulation of organic pollutants and heavy metals like lead, arseni…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Lake, Loryssa; Basta, Nicholas
  • Licensing Officer: Wilburn, Adri

Method for sensitizing solid tumors to immunotherapy
TS-065862 — The Need In the landscape of cancer treatment, the emergence of immunotherapy has shown remarkable promise. However, its efficacy is not universal across all cancer types, and resistance development poses a significant challenge. Hyperprogression, characterized by accelerated tumor growth, further …
  • College: College of Arts & Sciences
  • Inventors: Kural, Comert; Djakbarova, Umidahan
  • Licensing Officer: Wilburn, Adri

Targeted Delivery to Cancer Cells using Self-assembled, Camptothecin Nanotubes: Active and Passive Targeting
TS-065860 — The Need: Cancer remains one of the most pressing medical challenges of our time, demanding innovative solutions to enhance treatment efficacy while minimizing systemic toxicity. Conventional chemotherapy agents often suffer from poor solubility, instability, and indiscriminate cytotoxicity, necessi…
  • College: College of Arts & Sciences
  • Inventors: Parquette, Jonathan; Magliery, Thomas
  • Licensing Officer: Dahlman, Jason "Jay"

Advancing Canine Lung Cancer Care: Precision Diagnostics and Targeted Therapies
TS-065859 — FIELD: Revolutionizing Canine Lung Cancer Treatment The Need: Lung cancer in canines poses significant clinical challenges, mirroring the complexities of human lung cancer in non-smokers. With limited standard treatments beyond surgery, there's an urgent demand for advanced methods to assess, c…
  • College: College of Veterinary Medicine
  • Inventors: Lorch, Gwendolen
  • Licensing Officer: Dahlman, Jason "Jay"

Tomato Lines Resistant to Bacterial Spot (Rx-3, Xv3, QTL-11), Verticillium (Ve), and Fusarium (I)
TS-065858 — The Need: In the modern agricultural landscape, tomato crops face significant threats from bacterial spot, Verticillium, and Fusarium, leading to substantial yield losses and economic strain for growers. Addressing these challenges is crucial to ensure a sustainable and profitable tomato industry. …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Francis, David
  • Licensing Officer: Dahlman, Jason "Jay"

Soft Red Winter Wheat Line OH18-46-89
TS-065857 — The Need: In today's agricultural landscape, optimizing crop yield and quality is paramount to meet the growing demand for food. Farmers face the challenge of selecting crop varieties that offer resilience to various environmental stressors while maintaining high productivity levels. Additionall…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Sneller, Clay
  • Licensing Officer: Dahlman, Jason "Jay"

Malting Barley Variety RIL02FL-029
TS-065856 — The Need: As the demand for high-quality malting barley continues to rise, there is a pressing need for winter barley varieties that offer exceptional performance across various environmental conditions. Breweries and maltsters require reliable sources of malting barley to meet consumer demands for …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Stockinger, Eric
  • Licensing Officer: Dahlman, Jason "Jay"

Malting Barley Variety RIL523PFFN-033
TS-065855 — The Need: Breweries and malting facilities seek barley varieties that combine winter-hardiness, lodging resistance, early maturity, and high yield potential while meeting the stringent quality requirements of all-malt brewing. Meeting this demand ensures consistent and high-quality beer production, …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Stockinger, Eric
  • Licensing Officer: Dahlman, Jason "Jay"

Malting Barley Variety RIL02WI-013
TS-065854 — The Need: With the increasing demand for high-quality malting barley varieties, there is a pressing need for a winter barley line that can thrive in diverse environmental conditions while meeting the stringent requirements of the malting industry. Traditional barley varieties often struggle with win…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Stockinger, Eric
  • Licensing Officer: Dahlman, Jason "Jay"

Food-Grade Soybean Variety HS8-W179
TS-065853 — The Need: In the ever-evolving agricultural landscape, there is a critical need for food-grade cultivars that offer superior yields, enhanced protein content, and resistance to prevalent diseases. Farmers and agricultural stakeholders seek cultivars that not only optimize productivity but also ensur…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: McHale, Leah; Dorrance, Anne; Feller, Marcia; McIntyre, Scott; St Martin, Steven
  • Licensing Officer: Dahlman, Jason "Jay"

Winter Barley Variety- DH02UK-010
TS-065851 — There is a growing demand for winter barley varieties with enhanced traits such as winter-hardiness, lodging-resistance, and early maturity, particularly those suitable for malting purposes. Meeting this demand is essential for ensuring stable barley production and meeting the needs of the malting…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Stockinger, Eric
  • Licensing Officer: Dahlman, Jason "Jay"

Winter Barley Line DH02SP1-030
TS-065849 — The Need With the ever-evolving demands of the malting barley market, there's an urgent need for a variety that not only withstands winter conditions but also boasts superior qualities in terms of yield, lodging resistance, and maturity. Meeting the growing demand for malting barley while ensur…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Stockinger, Eric
  • Licensing Officer: Dahlman, Jason "Jay"

Improved Taraxacum kok-sagyz germplasm from interbred high rubber genotypes.
TS-065848 — The Need In today's dynamic agricultural landscape, there is an escalating demand for sustainable and high-yield crop varieties to meet global rubber production needs. Conventional rubber cultivation methods often face challenges such as susceptibility to diseases, environmental stress, and flu…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Cornish, Katrina; Amstutz, Nikita; Cardina, John; Fioritto, Ronald; McNulty, Sarah; Robinson, Ben; Zaborski, Debra
  • Licensing Officer: Dahlman, Jason "Jay"

mCherry Fluorescence-Producing Ehrlichia chaffeensis: Revolutionizing Bacterial Detection
TS-065847 — The Need: In today's world, rapid and accurate detection of bacterial pathogens is crucial for safeguarding public health and animal well-being. With the emergence of diseases transmitted by ticks and the increasing importance of understanding vector-borne infections, there's a pressing need…
  • College: College of Veterinary Medicine
  • Inventors: Rikihisa, Yasuko; Lin, Mingqun "Mingqun"
  • Licensing Officer: Dahlman, Jason "Jay"

Specific Pathogen Free Turkey Eggs
TS-065846 — The Need: With the persistent threat of avian diseases, ensuring the health and safety of turkey populations is of utmost importance to the poultry industry. Traditional methods of disease prevention have limitations, necessitating a technology that can reliably produce Specific Pathogen Free (SPF) …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Saif, Mo
  • Licensing Officer: Panic, Ana

Protease-free Bacillus subtilis host
TS-065845 — The Need: In the realm of biotechnology, the challenge of synthesizing enzymes, pharmaceuticals, and fine chemicals efficiently is paramount. However, the presence of multiple proteases secreted by Bacillus subtilis 168 during growth stages poses a significant obstacle to achieving optimal productio…
  • College: College of Arts & Sciences
  • Inventors: Zeigler, Daniel
  • Licensing Officer: Willson, Christopher

SUMO^RIT Tag: Revolutionizing Downstream Gene Translation
TS-065844 — The Need: In modern biotechnology and pharmaceutical industries, precise control over gene expression is paramount. However, conventional translation processes often lead to inefficiencies, resulting in reduced yields and compromised protein function. Meeting the demand for enhanced gene expression …
  • College: College of Arts & Sciences
  • Inventors: Law, Jamison
  • Licensing Officer: Willson, Christopher

Neorickettsia Isolate "Dai17"
TS-065843 — The Need Potomac horse fever (PHF) poses a significant threat to equine health, presenting as a severe and often fatal febrile diarrheal disease. Current understanding identifies Neorickettsia risticii as the sole causative agent, associated with digenean trematodes. However, recent research reveal…
  • College: College of Veterinary Medicine
  • Inventors: Rikihisa, Yasuko
  • Licensing Officer: Dahlman, Jason "Jay"

Neorickettsia Isolate "Dun17"
TS-065842 — The Need Potomac horse fever (PHF) poses a significant threat to equine health, presenting as a severe and often fatal febrile diarrheal disease. Current understanding identifies Neorickettsia risticii as the sole causative agent, associated with digenean trematodes. However, recent research reveal…
  • College: College of Veterinary Medicine
  • Inventors: Rikihisa, Yasuko
  • Licensing Officer: Dahlman, Jason "Jay"

Neorickettsia Isolate "May17"
TS-065841 — The Need Potomac horse fever (PHF) poses a significant threat to equine health, presenting as a severe and often fatal febrile diarrheal disease. Current understanding identifies Neorickettsia risticii as the sole causative agent, associated with digenean trematodes. However, recent research reveal…
  • College: College of Veterinary Medicine
  • Inventors: Rikihisa, Yasuko
  • Licensing Officer: Dahlman, Jason "Jay"

Revolutionizing Literacy Instruction with LetterWorks: Bridging Tradition and Technology
TS-065840 — The Need Incorporating Information and Communication Technologies (ICTs) into literacy instruction is imperative, especially for at-risk populations, yet research in this area remains limited. The demand for effective tools to enhance literacy learning among struggling readers is critical. Teachers…
  • College: College of Education & Human Ecology
  • Inventors: Rodgers, Emily; D'Agostino, Jerome
  • Licensing Officer: Dahlman, Jason "Jay"

3D printed hemlock twig key tag showing feeding locations of hemlock woolly adelgid (HWA) and elongate hemlock scale (EHS)
TS-065837 — The Need: In the fight against invasive species threatening our forests, rapid and accurate identification is paramount. Traditional methods for monitoring pests like the Hemlock Woolly Adelgid (HWA) and Elongate Hemlock Scale (EHS) can be time-consuming and imprecise, leading to delayed responses a…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Basnagala, Suranga; Perry, Kayla
  • Licensing Officer: Panic, Ana

3D printed Elm leaves to show Elm Zigzag Sawfly (Aproceros leucopoda) larval feeding damage.
TS-065836 — The Need: In today's agricultural landscape, precise identification and monitoring of pest damage are paramount for maintaining crop health and maximizing yields. Traditional methods often fall short in accurately assessing and addressing the impact of pests like the Elm Zigzag Sawfly (Aproceros…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Basnagala, Suranga; Perry, Kayla
  • Licensing Officer: Panic, Ana

CENT: Empowering Effective Partnerships
TS-065828 — The Need In today's interconnected world, stakeholder organizations face the challenge of navigating complex networks to address shared issues effectively. Whether it's climate change adaptation, healthcare management, or community development, the ability to identify and foster partnership…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Fried, Harrison; Ordonez, Kimberly
  • Licensing Officer: Dahlman, Jason "Jay"

Advancing Inclusive Education: Introducing the Student Evaluation of Inclusive Classroom Instruction
TS-065826 — The Need In higher education, fostering inclusive and culturally responsive classroom environments is imperative to address institutional racism and ensure equitable learning experiences for all students. To achieve this, instructors must demonstrate cultural sensitivity, responsiveness to individu…
  • College: College of Education & Human Ecology
  • Inventors: Arnold, Noelle; Luthy, Nicole; Penn, Carlotta; Pratt, Keeley
  • Licensing Officer: Dahlman, Jason "Jay"

IDEAS: Revolutionizing Early Childhood Education with Automated Interaction Analysis
TS-065825 — The Need: In early childhood education settings, understanding children's interactions, both social and linguistic, is paramount for effective teaching and development monitoring. However, manual observation and analysis of these interactions can be time-consuming and subjective, hindering educa…
  • College: College of Education & Human Ecology
  • Inventors: Gonzalez Villasanti, Hugo "Hugo"; Justice, Laura
  • Licensing Officer: Dahlman, Jason "Jay"

Clearinghouse for Evidence-based Programs and Practices for School and School District Improvement
TS-065824 — The Need: In today's educational landscape, the demand for evidence-based practices to enhance student outcomes is paramount. Educators seek efficient, accessible resources aligned with federal guidelines to drive improvement efforts effectively. However, navigating through the plethora of infor…
  • College: John Glenn College of Public Affairs
  • Inventors: Joyce, Erin; Knighton, Ryan; Maurer, Julie; Porter, Lauren
  • Licensing Officer: Dahlman, Jason "Jay"

RocketTechs: Igniting Entrepreneurial Ventures
TS-065823 — The Need: In today's rapidly evolving technological landscape, bridging the gap between innovative university technologies and entrepreneurial leaders is paramount. However, existing platforms often lack the efficiency and user-friendliness required for effective matchmaking. RocketTechs address…
  • College: Office of Business and Finance
  • Inventors: Morowit, Lauren; Turnbull, Cheryl
  • Licensing Officer: Dahlman, Jason "Jay"

Partnerships for Literacy (P4L): Bridging Communities for Enhanced Literacy
TS-065822 — The Need: In today's educational landscape, fostering meaningful partnerships between schools and families is paramount to enhancing literacy levels among students. However, many schools face challenges in creating sustained, goal-oriented engagements that develop the capacity of educators and f…
  • College: College of Education & Human Ecology
  • Inventors: Boone, Barbara; Wellman, Meredith
  • Licensing Officer: Dahlman, Jason "Jay"

Method for increasing English literacy through professional development with K-20 teachers
TS-065821 — The Need: In a rapidly evolving educational landscape, the demand for effective English language instruction in India is more pressing than ever. Yet, many educators face significant challenges in engaging students in meaningful conversations and writing exercises that align with their curriculum. T…
  • College: Newark Campus
  • Inventors: Rodgers, Adrian
  • Licensing Officer: Dahlman, Jason "Jay"

Student Success Dashboard: Transforming Education Through Data-Driven Support
TS-065820 — Ohio Student Success Dashboard: Revolutionizing Student Support The Need: Ohio and the national economy are undergoing a transformative shift, where traditional high school education no longer guarantees success in the job market. With nearly 60% of jobs requiring additional training beyond a high …
  • College: College of Education & Human Ecology
  • Inventors: Hawley, Joshua
  • Licensing Officer: Dahlman, Jason "Jay"

Global Competency Assessment: Revolutionizing International Business Readiness
TS-065819 — The Need: In today's interconnected global marketplace, businesses require accurate assessments of their employees' global competencies to thrive. Existing instruments often fall short, focusing narrowly on specific dimensions or merely perceived self-efficacy rather than comprehensive knowl…
  • College: Fisher College of Business
  • Inventors: Greenberger, David "David B. Greenberger"; Gomez-Bellenge, Francisco; Shenkar, Oded
  • Licensing Officer: Dahlman, Jason "Jay"

Streamline Your Building Design Workflow with AutoCAD to Revit Conversion Technology
TS-065818 — The Need In the architecture, engineering, and construction (AEC) industry, the need for seamless and efficient conversion of AutoCAD drawings to Revit models is paramount. As projects grow in complexity and scale, the ability to transition seamlessly between these platforms becomes essential for m…
  • College: Senior VP Admin & Planning
  • Inventors: Porostosky, Joseph; Palmer, Tracy; Pifher, David
  • Licensing Officer: Dahlman, Jason "Jay"

Empowering Financial Wellness: Scarlet and Gray Financial's Innovative Solutions
TS-065817 — The Need In today's dynamic financial landscape, individuals, especially students, require personalized and accessible financial guidance to navigate their financial journey effectively. Scarlet and Gray Financial recognizes the pressing need for tailored peer-to-peer financial coaching to empo…
  • College: Office of Student Life
  • Inventors: Patella, Michelle
  • Licensing Officer: Dahlman, Jason "Jay"

MyMoneyPath: Empowering Financial Wellness for All
TS-065816 — The Need: In today's fast-paced financial landscape, individuals often lack accessible and personalized tools to assess and improve their financial well-being. Many low and moderate-income populations, particularly first-time homebuyers, face unique challenges in navigating financial decisions. …
  • College: Office of Academic Affairs
  • Inventors: Moulton, Stephanie; Collins, J.; Loibl, Caezilia; Savikhin, Anya
  • Licensing Officer: Dahlman, Jason "Jay"

Targeting Telomerase to Treat Ocular Neovascular Disorders
TS-065809 — Therapeutic strategies for treating ocular neovascular disorders by targeting telomerase.
Choroidal neovascularization (CNV) is the principal driver of blindness in neovascular age-related macular degeneration (nvAMD). Abnormal blood vessel growth beneath the macular leads to retinal damage and severe vision loss. Discovering the involvement of VEGF in the underlying mechanisms driving …
  • College: College of Medicine (COM)
  • Inventors: Kerur, Nagaraj
  • Licensing Officer: Schultz, Teri

Treating Diabetes, Obesity, and Cardiovascular Disease by Reprogramming Skin
TS-065789 — Using tissue nano-transfection to reprogram skin cells to treat diabetes, obesity and/or cardiovascular health
The incidence of obesity and diabetes is skyrocketing, leading to chronic inflammatory conditions such as cardiovascular disease, autoimmune diseases, liver diseases, and cancer. Cardiovascular disease (CVD) is the leading cause of death across the US and worldwide and affects almost half of all ad…
  • College: College of Medicine (COM)
  • Inventors: Gallego Perez, Daniel; Higuita Castro, Natalia; Sen, Chandan
  • Licensing Officer: Schultz, Teri

Revolutionizing Cancer Immunotherapy with Novel Chimeric B-cell Epitope Peptide Vaccines
TS-065697 — Chimeric B-cell epitope peptide vaccines targeting human PD-L1 and/or CTLA-4 to induce immune response against the PD-1/PD-L1 signaling pathway.
The emergence of immune checkpoint inhibitors revolutionized cancer immunotherapy. Monoclonal antibodies targeting PD-1, PD-L1 and CTLA-4 have shown impressive clinical outcomes. The Need Despite their effectiveness, current monoclonal antibody treatments have limitations such as low response ra…
  • College: College of Medicine (COM)
  • Inventors: Kaumaya, Pravin
  • Licensing Officer: Schultz, Teri

European Corn Borer mating Cage
TS-065465 — The Need: The agricultural sector faces persistent challenges in controlling pests like the European Corn Borer (ECB), which can devastate corn crops, leading to significant economic losses. Traditional methods often prove inadequate, necessitating innovative solutions to combat these destructive in…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Michel, Andrew; Basnagala, Suranga
  • Licensing Officer: Dahlman, Jason "Jay"

3D-Printed Soybean Leaf
TS-065464 — The Need In modern agriculture, the ability to quickly and accurately identify diseases impacting soybean crops is critical for farmers to maintain yield and profitability. Traditional methods of disease identification can be time-consuming and imprecise, leading to potential losses. There is a cle…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Lang, Olivia; Michel, Andy
  • Licensing Officer: Dahlman, Jason "Jay"

Indolce™: Elevating Pudding to a Calming Experience
TS-065463 — The Need: In today's fast-paced world, consumers seek not just sustenance but also moments of tranquility amidst the chaos. Indolce™ meets this need by offering a decadent pudding snack infused with mood-boosting ingredients designed to soothe both the palate and the mind. With stress leve…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Melendrez Alvarez, Ronald; Choriego Marin, Rolando; Kosmerl, Erica; Miller, Celeste
  • Licensing Officer: Dahlman, Jason "Jay"

Rubber Cultivation for Increased Yield and Sustainability-The "Golf" advanced population
TS-065462 — The Need In the rubber industry, optimizing latex production while ensuring the sustainability of rubber-producing plants is essential. Rubber farmers face challenges such as fluctuating market demands, environmental pressures, and the need for consistent yield levels. To meet these challenges, the…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Cornish, Katrina; Fresnedo Ramirez, Jonathan; Wheeler, Brandon "Brandon"
  • Licensing Officer: Dahlman, Jason "Jay"

Antibiotic-free selection of plasmids for recombinant DNA technology applications
TS-065461 — The Need: In the field of modern biochemistry, the production of recombinant proteins in bacterial hosts like Escherichia coli is integral for both research and industrial applications. However, the traditional method of using antibiotics for selection in protein production is costly and contributes…
  • College: College of Arts & Sciences
  • Inventors: Gopalan, Venkat
  • Licensing Officer: Willson, Christopher

Targeted Nanobody Technology for Precise Antineoplastic Treatment
TS-065460 — The Need Cancer remains one of the most pressing medical challenges worldwide, necessitating novel therapeutic approaches to combat its proliferation. Despite advancements, targeted therapies are often limited by immune responses or cumbersome production processes. There's a growing demand for …
  • College: College of Arts & Sciences
  • Inventors: Magliery, Thomas; Palmieri, Dario; Ryan-Simkins, Michael
  • Licensing Officer: Willson, Christopher

Peptide-based inhibitor of host factor involved in HIV-1 replication
TS-065459 — The Need The emergence of HIV-1 infection continues to pose significant challenges in healthcare worldwide. Current treatment approaches primarily target viral components, leading to the development of drug resistance over time. There is a pressing need for innovative therapeutic strategies that di…
  • College: College of Arts & Sciences
  • Inventors: Musier-Forsyth, Karin; Tang, Yingke
  • Licensing Officer: Willson, Christopher

Precision RNA-PROTACs: Revolutionizing Therapeutic Targeting of Dysregulated Ribonucleoprotein Complexes
TS-065457 — The Need: In the realm of therapeutic development, there's a pressing need for precise targeting of dysregulated ribonucleoprotein (RNP) complexes to combat various diseases, particularly neurodegenerative disorders like ALS, Alzheimer’s, and Huntington’s diseases. Traditional metho…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"; Strong, Rebekah
  • Licensing Officer: Willson, Christopher

Revolutionizing RNA-Protein Interaction Mapping: Precision Proximity Labeling Technology
TS-065456 — The Need In modern biological research, there is a pressing demand for technologies that enable precise mapping of RNA-protein interactions within Ribonucleoprotein (RNP) complexes. Traditional methods often lack the capability to pinpoint these interactions at the level of secondary structure moti…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"
  • Licensing Officer: Willson, Christopher

Advancing RNA Detection with Innovative Peptide-Based Fluorescent Probes
TS-065455 — The Need: In modern biotechnology and biomedical research, there is an escalating demand for efficient tools that can accurately detect and analyze specific RNA sequences. The ability to precisely target and identify RNA molecules, particularly U-rich sequences, is crucial for various applications s…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; DeSantis, Christopher; Gopalan, Venkat; Liang, Yufeng; Mao, Jie; Marathe, Ila; Miao, Shiqin "Shiqin"
  • Licensing Officer: Willson, Christopher

Monoclonal Antibodies for Soybean Rust Diagnostic Assay
TS-065454 — The Need: As agriculture faces increasing challenges from plant pathogens, rapid and accurate detection methods are crucial to safeguarding crop yields and ensuring food security. Traditional methods of pathogen detection often suffer from delays in diagnosis, leading to significant crop damage and …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Dorrance, Anne; Luster, Douglas; McMahon, Michael; Miller, Sally
  • Licensing Officer: Dahlman, Jason "Jay"

Show More Technologies

Loading icon